Protein Alignment Orct2 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 640
• Identity: 148/640 - (23%)
• Similarity: 257/640 - (40%)
• Gaps: 103/640 - (16%)

  Fly     1 MGYDEAII-HLGDF-GRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLP- 62
            :.||.::: .||.. |.|||.:..|..:.::.:.|.:.:..|||.:|:|.|   ...|...:|.
  Rat    78 LDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWC---HGAGKGTELAG 139

  Fly    63 ---THLW----NLSYPENERCSYYDVDYTEEYLNG-------SIPRSSNETKTCSSYVYD---RS 110
               |..|    |.:.|.....|......|....|.       |.|...|....|..:.:|   |:
  Rat   140 ATVTGRWGDMGNWTSPSATPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCECHAWDYGIRT 204

  Fly   111 KYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLA 175
            ..:.:.|::|:|||...:....:....::|::.|.::.|.::|..||:|:|..|::..::||:..
  Rat   205 GLVQNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSVIFILIFGLTV 269

  Fly   176 GVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFV 240
            .::.....::..|...|...:|:.|..|.:.:|:..|.||....:........|..|....|...
  Rat   270 ALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALC 334

  Fly   241 HDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARF-----NKVEISDEAL 300
            .||:.||..:..|.|:.:.|:.|.|||.|||:       |....:.|.:.     .|..:|.|
  Rat   335 RDWQVLQALIICPFLLMLLYWSIFPESLRWLM-------ATQQFESAKKLILYLTQKNCVSPE-- 390

  Fly   301 SELLDEGENSEEKAKQKLEDQELDEGPPP-SVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWN 364
                     |:.|......::||...|.. .:..:....||.:..:::.::.|...|:::  .:.
  Rat   391 ---------SDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHH--CFA 444

  Fly   365 TSNLGGNV----LLNFVIS----GAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIP 421
            .|.:|..|    |.||...    .::.:.:.:.:.|.:...|||.   |.|:...|:.||: ::.
  Rat   445 RSMMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVRFLGRRG---GLLLFMILTALAS-LLQ 505

  Fly   422 QRMHTLI----------------------------VACAMLGKLAITASYGTVYIFSAEQFPTVV 458
            ..:..||                            :|.:::|..|..|.......|.||..|||:
  Rat   506 LGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVI 570

  Fly   459 RNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPMLETIAD 523
            |...||.....|....:.||.:.........|..:|....||:..:..|||||:.::.:.|.||:
  Rat   571 RCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIAN 635

  Fly   524 GERFGK------KTKADVYLETGQELRAPEAQPLK-----GSGETNGSTIANGHK 567
            ||.:.:      |......|.|..||:  :...|.     |.|.:.|:| |||.|
  Rat   636 GEHYTRQPLLSHKKGEQPLLLTNAELK--DYSGLHDVAAVGDGLSEGAT-ANGMK 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	126/569 (22%)
		MFS	127..503	CDD:119392	88/417 (21%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		4/25 (16%)
		MFS_SLC22A23	187..608	CDD:341002	95/444 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940