Protein Alignment Orct2 and Sv2b

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001103223.1
• Gene: Sv2b / 64176
• MGIID: 1927338
• Length: 683
• Species: Mus musculus
• Alignment Length: 555
• Identity: 114/555 - (20%)
• Similarity: 184/555 - (33%)
• Gaps: 202/555 - (36%)

  Fly   139 LGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAY 203
            ||::.|:.:.|.|:||.|||.:|..||.|...|..|:.....|..:.|.||:.|....|...:.:
Mouse   156 LGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVF 220

  Fly   204 VVAMEMVGPDKR----LYAGIFVM--------MFFSV------GFMLTAVFAYFVHDWRWLQIAL 250
            ....|.:..:||    .:.|||.|        |.:|:      ||.:..  .|..|.||...|..
Mouse   221 AYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGT--NYHFHSWRVFVIVC 283

  Fly   251 TLPGLIFMFYYWIIPESARWLLLKGRKDCA--------IANMQKAARFNKV-EISDEALSELLDE 306
            .||..:.|.....:|||.|:||..|:.|.|        ..||:......|| .:|.....:.:||
Mouse   284 ALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDE 348

  Fly   307 GENSEEKA---------------KQKLEDQELDEGPPPSVWD--LFCYPN-LRRKTLLIFLDWLV 353
            ....:...               ||              |||  |:|... .|..||::.:.|..
Mouse   349 FIEIQSSTGTWYQRWLVRFMTIFKQ--------------VWDNALYCVMGPYRMNTLILAVVWFT 399

  Fly   354 TSGVYYGLS-WNTSNL----------------GGNV---LLNFVISGAVE----------IPAYI 388
            .:..||||: |....:                |.:|   .:||.:...:.          |..|.
Mouse   400 MALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYF 464

  Fly   389 ----------------------------------------------------------------- 388
                                                                             
Mouse   465 KHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMD 529

  Fly   389 ------FLLLTLNRWGRRSILCGCLV------------MAGLSLLATVIIPQRMHTLIVAC---- 431
                  ||:..::..|..|:|.|.::            |.|.|:|.:.          |.|
Mouse   530 FEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISA----------VCCFFLF 584

  Fly   432 ------AMLGKLAI-----TASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAP--FLNFL 483
                  ||:|...:     .|::..:.:.:.|.:||..|..|.|..:.:.:...::..  |.:|:
Mouse   585 FGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFV 649

  Fly   484 ATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPML 518
            . |.|.:|:|:..:..:..||::|.||||..:.::
Mouse   650 G-ITKVVPILLAAASLVGGGLIALRLPETREQVLM 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	114/555 (21%)
		MFS	127..503	CDD:119392	107/538 (20%)
Sv2b	NP_001103223.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73
		synapt_SV2	8..683	CDD:130366	114/553 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940