Protein Alignment Orct2 and slc22a31

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_699154.4
• Gene: slc22a31 / 570565
• ZFINID: ZDB-GENE-130530-858
• Length: 610
• Species: Danio rerio
• Alignment Length: 586
• Identity: 156/586 - (26%)
• Similarity: 255/586 - (43%)
• Gaps: 112/586 - (19%)

  Fly     1 MGYDEAII-HLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPD-FRC-------------- 49
            |.|:..|. .:|.:|||.:||.......:..|:.:....||....|: :.|
Zfish     1 MEYETKIYPQVGGYGRYNRIITLFSWFPNFAVSLNLFTDVFFTLVPESYHCKPDQALLPPSALLS 65

  Fly    50 ----------ALPFENGSSYDLPTHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCS- 103
                      .:|:..||.:   :|.....||.|..      :||::.        ..:..:|:
Zfish    66 NLSRQAYLNLTVPWLKGSGF---SHCELYKYPVNVS------NYTDDV--------ERDVVSCTG 113

  Fly   104 SYVYDRSKYL-NSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVI 167
            .:.:.:...| |:.||||||||...:........||.|..||.|:.|.|.|..||:..|..|:|:
Zfish   114 GWEFSKPAGLQNNLVTEWNLVCDDYWKIPLQHICFMTGWTLGYILLGTLCDWLGRRRALLLSVVL 178

  Fly   168 QVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSV-GFM 231
            ..|.|::|.::.....:.|.||..|:|.:||||.:|:..:|...|..||...: |..||:| ..:
Zfish   179 SGLLGIMACISNSPSAFPFLRLCQGSTLAGVFLSSYIARLEWCDPSHRLMVSM-VSGFFAVFAEL 242

  Fly   232 LTAVFAYFVHDWRWLQIALTLPGLIFMFYYW----IIPESARWLLLKGR----KDCAIANMQKAA 288
            |....|....||..||...||| |:.:..||    :.|||.||||...:    |:|    :|..:
Zfish   243 LLPGLAVLCRDWPVLQAVATLP-LLLLLSYWCCASVFPESPRWLLATAQIPQAKEC----LQSFS 302

  Fly   289 RFNKVEISDE------ALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLR---RKT 344
            ..|.:.:|||      .|||:                |:...|...|....:|...:.|   :..
Zfish   303 ARNGMCVSDELYPAETLLSEI----------------DEAFPEDVQPEYHHVFELRHTRVIWKNC 351

  Fly   345 LLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNF---VISGAVEIPAYIFLLLTLNRWGRRSILCGC 406
            |::.....:.:|:.|..:.|......:...::   |::||:   |.|||.:|::|:|||.:|...
Zfish   352 LILGFTLFIGTGIQYCFTRNLHIYSPHFYFSYFLRVLTGAL---ACIFLCVTVDRYGRRGMLLLA 413

  Fly   407 LVMAGLSLLATVIIPQRMH-TLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALG------ 464
            .::.|||.|..:.:.|.:| .|::..:::|.|:..|.......|.:|..||:||...||
Zfish   414 AIITGLSSLLLLALTQYLHGGLVLVLSVVGLLSSQALAMLSMFFGSEVMPTIVRGGTLGLIMSAG 478

  Fly   465 ----AASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHNKPMLETIADGE 525
                |||.:..:......||:.          :|..|..:::.|..:||||:.:||:.:::.|||
Zfish   479 CIGMAASSLMELQNNGGYFLHH----------VIFASFAVLSVLCIMLLPESKHKPLPDSLKDGE 533

  Fly   526 R 526
            |
Zfish   534 R 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	149/567 (26%)
slc22a31	XP_699154.4	MFS_SLC22A31	104..518	CDD:341001	124/456 (27%)