Protein Alignment Orct2 and sv2a

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 538
• Identity: 102/538 - (18%)
• Similarity: 178/538 - (33%)
• Gaps: 173/538 - (32%)

  Fly   139 LGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAY 203
            ||:::|:.|:|.|:|:.||:..|..||.|..:|...:.....|.::.|.||:.|....|...:.:
Zfish   205 LGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVF 269

  Fly   204 VVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVF----------------AYFVHDWRWLQIALTL 252
            ....|.:..:||.....::.||:.:|.:..|..                ||..|.||...:....
Zfish   270 SYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAF 334

  Fly   253 PGLIFMFYYWIIPESAR-----------WLLLKGRKDCAIANMQKAAR----FNKVEISD-EALS 301
            |.:..:.....:|||.|           |::||...|   .||:....    |:...|.. :.:.
Zfish   335 PSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHD---TNMRAKGYPERVFSVTTIKTVKQMD 396

  Fly   302 ELLDEGENS---EEKAKQKLEDQELDEGPPPSVWDLFC---YPNLRRKTLLIFLDWLVTSGVYYG 360
            ||:|.|..:   .::.:.||.:..      ..||..|.   .|..||.|.::...|...|..|||
Zfish   397 ELVDMGGEATAWHQRWRIKLTNLF------HQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYG 455

  Fly   361 LS-W-----------------------------------NTSNLGG----NVLLNFVISGAV--- 382
            |: |                                   |..:..|    |..||..:...|
Zfish   456 LTVWFPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFED 520

  Fly   383 ----------------------------------------------------------------- 382
                                                                             
Zfish   521 SLFEECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNA 585

  Fly   383 -------------EIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAML 434
                         .:|..|...|.:::.||..:|.|..|::.:|.. .:........:|....:.
Zfish   586 YMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVISCVSCF-FLSFGNSESAMIALLCLF 649

  Fly   435 GKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMM--APFLNFLATIWKPLPLLICGS 497
            |.::| ||:..:.:.:.|.:|:..|..|.|..:.:.:::.::  :.|.:|:. |.|.:|:|....
Zfish   650 GGISI-ASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSFVG-ITKAVPILFASG 712

  Fly   498 LTLVAGLLSLLLPETHNK 515
            .......|:|.||||..:
Zfish   713 ALAAGSFLALKLPETRGQ 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	102/538 (19%)
		MFS	127..503	CDD:119392	96/524 (18%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	102/538 (19%)
		MFS	162..725	CDD:119392	98/531 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940