DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct2 and LOC566640

DIOPT Version :9

Sequence 1:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	XP_009291426.1	Gene:	LOC566640 / 566640	-ID:	-	Length:	511	Species:	Danio rerio

Alignment Length:	518	Identity:	138/518 - (26%)
Similarity:	228/518 - (44%)	Gaps:	74/518 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 AFHKLAG-----VF-LLAKPDFRCALPF--------ENGSSYDLPTHLWNLSYPENER--CSYYD 80
            ||.:|||     || :|..|.|..|..|        ....|.|:.|...|.|...|..  .|:.|
Zfish     7 AFPRLAGTLQIHVFAILTLPIFFTAFTFFVDVFTLHITPCSVDIATKTLNRSVDSNVSIFASWTD 71

  Fly    81 VDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGS 145
                    |.|.|.||......:.:.:.::.|                         |.|:|:||
Zfish    72 --------NHSDPTSSQTCLKANHFAHGQATY-------------------------MTGLLIGS 103

  Fly   146 IVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMV 210
            ::.|.||||||:|.:|.....|..:..|:....|....|..||.:.|.:...:.:..|.:.:|..
Zfish   104 LIGGALSDKYGKKILLICCTAIHAVATVIVAFLPYVPVYLTARAISGVSCCAIHICTYSLGVEWS 168

  Fly   211 GPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKG 275
            .|..|::........||:|.|..|..|:....|....:||.:|.::|:..|:.:|||.|||||..
Zfish   169 LPKYRIWPPTLFSFIFSLGMMGLAAVAFLSSTWIQFHLALGIPQILFLPLYFFLPESPRWLLLNK 233

  Fly   276 RKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNL 340
            |       |:....:......|:...:||....::|  |::.|.::...|  ..|.:..|..|.:
Zfish   234 R-------MKTLESYQNRSSKDKRYLDLLLHSVDNE--AQKSLSEKSSTE--TRSNFTNFTSPII 287

  Fly   341 RRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCG 405
            ..:..::......::..|||:.::..:.|.|:.|....||..|.|: :.|...|.|||||....|
Zfish   288 LLRLFIMSYIGFASALTYYGICFSIGSFGVNIYLAQFFSGLSEAPS-LLLPFLLKRWGRRPFTMG 351

  Fly   406 CLVMAGLSLLATVIIPQ--RMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASM 468
            .|.::|:|.:.::::.:  .|..|::..|::|||.:.::|....::..|.||||:|...:|..|:
Zfish   352 SLFLSGISCMLSLLVSKFCNMPALVMTLALMGKLCMQSTYCVSTLYGIELFPTVIRQKCVGVVSL 416

  Fly   469 VAR----ISGMMAPFLNFLATIWKPLPLLICGS-LTLVAGLLSLLLPETHNKPMLETIADGER 526
            ..|    |:.:|:|....      |||.:|..| ..::...|.||||||...|:.:|:.:.|:
Zfish   417 CYRVACIINAVMSPEGGI------PLPAMISYSGGPIIGAALCLLLPETSGIPLPDTVHECEK 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	136/510 (27%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	102/382 (27%)
LOC566640	XP_009291426.1	MFS	93..455	CDD:119392	104/404 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940