Protein Alignment Orct2 and slc22a15

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_031751719.1
• Gene: slc22a15 / 448510
• XenbaseID: XB-GENE-959503
• Length: 560
• Species: Xenopus tropicalis
• Alignment Length: 580
• Identity: 184/580 - (31%)
• Similarity: 277/580 - (47%)
• Gaps: 83/580 - (14%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLIC-LTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTH 64
            |..:.|:..:|:.|.||..:.||:. |..:..|...:....|.|.|                |.|
 Frog    27 MEVEGALKLVGEMGIYQIYLSFLLAVLLQLYSATEAIIITILGATP----------------PYH 75

  Fly    65 LWNLSYPEN-ERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDF 128
            ..|.|...| .|...|......|..:|.:....|.|               |.|:||.||.|..:
 Frog    76 WMNDSLTANGSRGKQYGSQLPAEGEHGHVVFDGNFT---------------SIVSEWFLVGGAAY 125

  Fly   129 MAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGA 193
            ..:.|.|::..|||:|.|.||||||::||||:....|.::|:|.|:..:.|.:..:...|.:||.
 Frog   126 EVSVSSSVYFGGVLIGVISFGQLSDRFGRKPVYVTGLALEVVFAVMNALTPIFPLFLLTRFLVGV 190

  Fly   194 TTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIFM 258
            ...|:.|||:|:..|.:|......||....:.|:||....|:..||:..||.|.:.:.:.|...:
 Frog   191 MNGGMSLVAFVLLNECIGASYWAAAGSLGSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAAVL 255

  Fly   259 FYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQ-KLEDQE 322
            .....||||.|||..:||                   ..||...||..|..:..|... .|..::
 Frog   256 ALSLCIPESPRWLHAQGR-------------------LREAQESLLSLGRRNRRKVTSFTLCPRQ 301

  Fly   323 LDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAVEIPAY 387
            .|.....::..::....||::||::...|.|.|.|||||:.::.:|||::.||..:||..|:|||
 Frog   302 KDSAHSANILTIYSNAILRQRTLIMMWVWFVCSLVYYGLTLSSGDLGGDIYLNLALSGLAELPAY 366

  Fly   388 IFLLLTLN--RWGRRSILCGCLVMAGLSLLATVIIPQR----------MHTLIVACAMLGKLAIT 440
            ...:..:|  |.|||..|.|.|.:.|.:.|..:::|.:          ..||    ::||||.|:
 Frog   367 PLCMYLINHKRVGRRGSLAGFLCVGGGACLLIMLVPGKTGSGPLSVLNSQTL----SLLGKLNIS 427

  Fly   441 ASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLL 505
            |::..|||:|:|.:||.|||:.:|..||.:||.|::|||:..|......||.::.|:..:.||||
 Frog   428 AAFNIVYIYSSELYPTCVRNLGMGVCSMFSRIGGIIAPFIPALRFAHWALPFIVFGAAGVSAGLL 492

  Fly   506 SLLLPETHNKPMLETIAD--GERFGKKTKADVYLETGQE--LRAPEAQPLKGSGETNGST 561
            |||||||.:.|:.||:||  |..:.:       ||...|  |..|:|:.   ...||||:
 Frog   493 SLLLPETLSAPLPETLADLRGAPYRR-------LEPDGEAMLHRPQAEL---GAFTNGSS 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	167/523 (32%)
slc22a15	XP_031751719.1	MFS	90..497	CDD:475125	145/444 (33%)