DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct2 and CG7084

DIOPT Version :9

Sequence 1:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	557	Identity:	146/557 - (26%)
Similarity:	260/557 - (46%)	Gaps:	69/557 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GDFGRYQKIIYFLICLTSIPVAFHKLAG-------VFLLAKPDFRCALPFENGSSYDLPTHLW-N 67
            |:.||||.:..|:.      |.....:|       :..|..||..|.:|....:::.|..  | :
  Fly    42 GNHGRYQTLYNFVF------VGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEE--WRD 98

  Fly    68 LSYPEN---------ERCSYYDVDYTEEYLNGSIPRSSNETKT---C-SSYVYDRSKYLNSAVTE 119
            ::.|:.         ..|..:.::::|  :......:||.|||   | :.:.||::.|.::..|:
  Fly    99 ITLPKQADNRGRKTFSNCEMFQMNFSE--ITDWSAWNSNLTKTTEACQNGWSYDKTWYESTIPTD 161

  Fly   120 WNLVCGRDFMAATSDSLFMLG---VLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEY 181
            .|.||.:|....   ::|::|   .:.||.:.||:.|.|||:.:.:.|:|...| |.|..:...
  Fly   162 HNWVCAKDLFVT---NVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSL-GRLGSIMCT- 221

  Fly   182 FTYTFARLM---VGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDW 243
            .:||:..:|   ||.|.:.:|....::.||:...:.|.....|....:|:|..|..:..:::..|
  Fly   222 SSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHW 286

  Fly   244 ---RWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFN--KVEISDEALSEL 303
               .||....|...|:|..|   :.||.|||:.|.|...||..:||.|:.|  :.:::::.|:|:
  Fly   287 DSFMWLTSIPTAMVLLFSKY---VIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEKELAEI 348

  Fly   304 LDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNL 368
            .     |.:|       |::..|    :..||....|.|.|.::...|.|.:..|:.|...:|.:
  Fly   349 Y-----SRDK-------QDVTYG----IASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRM 397

  Fly   369 GGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVI--IPQRMHTLIVAC 431
            .||..|||:....||||||:......:.:|||.......:::.::.|..::  ..:|...|::..
  Fly   398 AGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIYL 462

  Fly   432 AMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFL-ATIWKPLPLLIC 495
            |...|.....::.||.:...|.:||.:|...:...:::|...|::||:|.:| .|:....|..|.
  Fly   463 ATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYIL 527

  Fly   496 GSLTLVAGLLSLLLPETHNKPMLETIADGERFGKKTK 532
            |.|.|:.|:.:|.||||.:|.:.:|:.:...|||..|
  Fly   528 GVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDK 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	141/543 (26%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	103/389 (26%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	133/515 (26%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	102/378 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	6.060