DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct2 and CG4459

DIOPT Version :9

Sequence 1:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	119/546 - (21%)
Similarity:	221/546 - (40%)	Gaps:	88/546 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHL--WNLSYPEN 73
            |.|||:|.....||.|..||.|:  ...:.:...|     .|::.    :|..|.  ||:|..:.
  Fly    26 GSFGRWQLRTILLIFLCKIPSAW--FTAIIIYTAP-----YPWKG----ELVCHPADWNVSRSQT 79

  Fly    74 ERCS--------------YYDVDYTEEYLN----GSIPRSSNETKTCSS------------YVYD 108
            |...              .::||....|.|    |.:.....|.....|            :|..
  Fly    80 EHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEHVEH 144

  Fly   109 RSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGV 173
            |:.| .|.:::::|:|.|..:.|.:.|...||.|:|.::......|...:.::...::.|:..|.
  Fly   145 RTDY-KSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGN 208

  Fly   174 LAGVAPEY--------FTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGF 230
            |.|:...|        .|..|..||.   |||.|::     .::.....|:.......:|:|:|.
  Fly   209 LTGLVDTYQLHIYFRCLTSIFCALMY---TSGQFIL-----NDITSGKARIIVVTLSELFWSMGL 265

  Fly   231 MLTAVFAYFVHDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEI 295
            :|....:.:..:|.:|.:|::...::.::.:..|.::.||||...|.:.|:..:.::|.:|..::
  Fly   266 VLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRKV 330

  Fly   296 SDEALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYG 360
            ......:|.....:.::|:|||....:        |||   ....|.:.:.|.|.|.....:|..
  Fly   331 PLTLDVQLTMYANDLDQKSKQKHSYCQ--------VWD---GETKRSQLVYIHLIWGGAMVLYNI 384

  Fly   361 LSWNTSNLGG-NVLLNFVISGAVE-IPAYIFLLLTLN-----RWGRRSILCGCLVMAGLSLLATV 418
            :.....|||. .|.:|....|..| :..::.|.|.|.     ||..     ..:::||||.....
  Fly   385 ILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAG-----NLMIIAGLSTYLIW 444

  Fly   419 IIPQ-----RMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAP 478
            ::|:     |...|.:...::.|:|.:||...:...::|......|.|.:.:....:|:..:..|
  Fly   445 LLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLFCP 509

  Fly   479 FLNFLATIWKPLPLLICGSLTLVAGL 504
            ||:.|..|...:|:.|..::..:.||
  Fly   510 FLSCLTVIHHLVPITILATMGWIYGL 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	119/546 (22%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	84/395 (21%)
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	119/546 (22%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	86/396 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450238
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950