DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct2 and CG14856

DIOPT Version :9

Sequence 1:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster

Alignment Length:	581	Identity:	145/581 - (24%)
Similarity:	256/581 - (44%)	Gaps:	51/581 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRC-ALPFENGSSYDLPTH 64
            |.:||.::..||..|||.::..|..|....|:.|..|...:...||..| ....||.|..::...
  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSYAEIAAI 67

  Fly    65 LWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFM 129
            ......|...|.:..::|       ||...:|:|  .|:.::|.......|...:.|.||...:.
  Fly    68 YAPFKRPSCTRLASINMD-------GSNATASSE--PCNRWIYHYDHGFISMNADLNWVCDDAYK 123

  Fly   130 AATSDSLFMLGVLLGSIVFGQLSDKYGR-KPILFASLVIQVLFGVLAGVAPEY----FTYTFARL 189
            |....|||.:|.:.|:::||.|.|:.|| |.::.|:..     |.|...|..:    .|::.:|.
  Fly   124 ARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCC-----GFLGDSATIFAETLLTFSASRF 183

  Fly   190 MVGATTSGVFLVAYVVAMEMVGPDKR-LYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLP 253
            :.|........:.:::.:|.|.|..| :...:.:.:|:.:|.:..:....::..||...:...||
  Fly   184 VSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALP 248

  Fly   254 GLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDE---GENSEEKAK 315
            .|:...:|::|.|||:||:.:...|.|...:::.|:||:.::| ||..||..:   .:.||.:::
  Fly   249 QLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVS-EADYELFRQHCKTKESEARSQ 312

  Fly   316 QKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISG 380
            ..::.|       ..:.|.|..|.||.:.:.:.:.:.:.:..|..:|.|...|..:..:.|.:..
  Fly   313 MSMQKQ-------ARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFA 370

  Fly   381 AVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVII----PQRMHTLIVACAMLGKLAITA 441
            ....|:.||.......:||:......:...||....|.|:    .|...|::|...::.:..|:.
  Fly   371 LTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATVMVCLLLMCRFGISV 435

  Fly   442 SYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLS 506
            :.|:....|.|..||.||:..|....:.|.....::||:..|.|.::....:|...|.||:..:.
  Fly   436 TTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAWIC 500

  Fly   507 LLLPETHNKPMLETIADGERFGKK----------TKADVYLETGQELRAPEAQPLKGSGET 557
            |||.||.||.:..|:|:||.|||.          .|||.:     :|.|...:.|.|...|
  Fly   501 LLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQH-----DLSADTIEKLMGDKRT 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	127/522 (24%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	91/388 (23%)
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	127/522 (24%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	91/386 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458391
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	3.940