Protein Alignment Orct2 and slc22a6l

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_996960.2
• Gene: slc22a6l / 404609
• ZFINID: ZDB-GENE-040426-2249
• Length: 560
• Species: Danio rerio
• Alignment Length: 546
• Identity: 161/546 - (29%)
• Similarity: 275/546 - (50%)
• Gaps: 43/546 - (7%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFEN--GSSYDLPT 63
            |.:.:.:..:|..||:|.:...|:.:..:.:|.|.|...|:.|.|...|. |..|  .||.|...
Zfish     1 MAFSDLLEQVGSTGRFQVLHVTLLSMPILMMASHNLLQNFVAAVPPHHCQ-PHANLSMSSTDAMD 64

  Fly    64 HLWNLSYP-----ENERCSYY--------DVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSKYLN 114
            .| ..:.|     :.|||..|        .::.:|...:.|:  :..||::| ..:.|:.::..:
Zfish    65 VL-RATVPLGLNGKLERCKRYTTPQWQILSLNTSESLWDESM--AETETQSCEDGWFYNMTEMSS 126

  Fly   115 SAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAP 179
            :.:|||:|||....:...|.:.:|.|||:|:||||.|||::||:.:|..|.::..:.|.....:.
Zfish   127 TIITEWDLVCDYRALKQMSQTTYMGGVLVGAIVFGGLSDRFGRRVLLLISNLMMAIGGTCVAFST 191

  Fly   180 EYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWR 244
            .:..:...|:..|...||:.|.::.:.:|.:....|...|......::.|.::.|..||.:.|||
Zfish   192 SFTMFCVFRVCCGMALSGLVLNSFSLIVEWIPTRVRTVVGTGTGYCYTTGQLILAAVAYCIRDWR 256

  Fly   245 WLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFN-------KVEISDEALSE 302
            ||.:|::||..:...|.|...||||||:|..:.:.|:.|::..||.|       |:::      |
Zfish   257 WLTLAVSLPFYVSFLYSWWFLESARWLVLTKKPEQAVKNLKTVARINGRSAEGDKIDL------E 315

  Fly   303 LLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSN 367
            :|.|....|....:          ...|..||.....:|..|:.:...|..||..|||||.:...
Zfish   316 MLQESMKKEMACSK----------GSYSALDLLRTSTMRTITICLSAVWFSTSFAYYGLSMDLQK 370

  Fly   368 LGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACA 432
            .|.::.|..:|.|||:|||.|.:.:.::..|||...||.||:||:.:|..:::|..:..|..:.|
Zfish   371 FGVSIYLIQIIFGAVDIPAKIIVTICMSMLGRRPSQCGALVLAGIMILINLLVPSDLQMLRTSLA 435

  Fly   433 MLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGS 497
            ::||..:.||:...|:::.|.:|||:|...:|..||:||...|:||.:..|...:..:|..|.|.
Zfish   436 VIGKGCLAASFNCCYLYAGELYPTVIRQSGMGWVSMMARFGAMVAPMVLLLGDDYPWIPGFIYGG 500

  Fly   498 LTLVAGLLSLLLPETHNKPMLETIAD 523
            ..:|:|:.:..||||.::|:.:||.|
Zfish   501 APIVSGIFAFFLPETLSQPLPDTIQD 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	157/531 (30%)
slc22a6l	NP_996960.2	MFS_SLC22A6_OAT1_like	108..513	CDD:341004	127/420 (30%)