Protein Alignment Orct2 and Slc22a20

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 572
• Identity: 183/572 - (31%)
• Similarity: 295/572 - (51%)
• Gaps: 39/572 - (6%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPT-- 63
            |.:.:.:..||..||:|.:...|:.|....:|.|.....|..|.|...|..|    ::|..||
Mouse     1 MAFTDLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHP----ANYTEPTTN 61

  Fly    64 --HLW-NLSYPEN-----ERCSYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSKYLNSAVTE 119
              .:| ..:.|.|     |.|..| |:.....|..:.......|:.| ..:|||||.:.::.|.|
Mouse    62 VSGVWLRAAIPLNQHGDPEPCRRY-VEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVME 125

  Fly   120 WNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRK-PILFASLVIQVLFGVLAGVAPEYF- 182
            |:|||....:...:.|::|.|||:|:.:||.|:|:.||| |::::.|.:.|     :|.|..|.
Mouse   126 WDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAV-----SGAATAYVG 185

  Fly   183 ---TYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWR 244
               .|...|.::|.|.||:.|.:..:.:|.:....|..|||.:...|::|.::.|..||.:..||
Mouse   186 SFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFSFTLGQLILAGVAYLIRPWR 250

  Fly   245 WLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGEN 309
            |||.|::.|.|:|..|.|.:|||:|||||.|:...|:.|:||.|..|..:...|.|
Mouse   251 WLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERL--------- 306

  Fly   310 SEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLL 374
            :.|.....::|:........|:.|||..|.:||.|..:...|...|..||||:.:....|.::.|
Mouse   307 TTEVVSSYIQDEFASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYL 371

  Fly   375 NFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAI 439
            ...:.|.::|||.:....|:...|||:.:...|::|||.::|.:.:|:.:.||....|.|||..:
Mouse   372 VQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCL 436

  Fly   440 TASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGL 504
            .:|:..||:|:.|.:||.:|.:.:|.||:.||:.|::||.:..|..|...||.:..|:.:::||:
Mouse   437 ASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGM 501

  Fly   505 -LSLLLPETHNKPMLETIADGERFGK--KTKADVYLETGQ-ELRAPEAQPLK 552
             ::..|.||.|.|::||||..||..|  ::|.|...::.: .|:...|.|||
Mouse   502 AVACFLTETRNVPLVETIAAMERRVKQGRSKRDTEQKSEEISLQQLGASPLK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	167/525 (32%)
		MFS	127..503	CDD:119392	123/380 (32%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	167/525 (32%)
		MFS	138..507	CDD:119392	125/382 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		8/28 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.980