Protein Alignment Orct2 and Slc22a15

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001101177.1
• Gene: Slc22a15 / 310732
• RGDID: 1311184
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 576
• Identity: 184/576 - (31%)
• Similarity: 282/576 - (48%)
• Gaps: 64/576 - (11%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLIC-LTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTH 64
            |..:||...:|:.|.||..:.||:. |..:.||...:....:.|.|.:.          :|:...
  Rat     1 MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYH----------WDMAEL 55

  Fly    65 LWNLSYPENERCSYYDVDYTEEYL--NGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRD 127
            |.|.|:  :.:.|.....:.:..|  |||         ....:|:..:.: .|..:||.|:..|.
  Rat    56 LPNQSH--SNQSSGKGQAFGDWLLTANGS---------EIHKHVHFSNSF-TSIASEWFLIANRS 108

  Fly   128 FMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVG 192
            :..:.:.|.|..||.:|.|.||||||::|||.:......:.:||.:..|.:|.|..:...|.:||
  Rat   109 YKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVG 173

  Fly   193 ATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGLIF 257
            ....|:.|||:|:..|.||......||....:||:||....|:..||:..||.|.|.:.|.|.:.
  Rat   174 MMNGGMSLVAFVLLNECVGAAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVV 238

  Fly   258 MFYYWIIPESARWLLLKGRKDCAIANMQKAARFNK-----VEISDEALSELLDEGENSEEKAKQK 317
            ......||||.|||..:||...|...:...|:.|:     ..::..|.....:.|
  Rat   239 FLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTFSLTHPANRSYRETG---------- 293

  Fly   318 LEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISGAV 382
                        |..|||.|..|...||::...|.|.|.|||||:.:..:|||::..|..:||.:
  Rat   294 ------------SFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLI 346

  Fly   383 EIPAYIFLLLTLN-RW-GRRSILCGCLVMAGLSLLATVIIPQRMHTLIVA------CAMLGKLAI 439
            |||:|...:..:| || ||:..|...|.:.||:.|..:.:|::..|.:.|      .::||||.|
  Rat   347 EIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTI 411

  Fly   440 TASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGL 504
            :|::..|||:::|.:|||:|||.||..||.:|:.|::|||:..|..:...||.::.|:..|.:||
  Rat   412 SAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATGLTSGL 476

  Fly   505 LSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEAQPLKGSGETNGS 560
            ||||||||.|.|:|||.:|.:.:..:...:..|.. |.|..|  ||| |...:.||
  Rat   477 LSLLLPETLNSPLLETFSDLQMYSYRRLGEEALSL-QTLDPP--QPL-GKASSLGS 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	168/524 (32%)
Slc22a15	NP_001101177.1	MFS_SLC22A15	71..469	CDD:340935	137/429 (32%)