Protein Alignment Orct2 and Slc22a15

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_001034460.2
• Gene: Slc22a15 / 242126
• MGIID: 3607704
• Length: 544
• Species: Mus musculus
• Alignment Length: 582
• Identity: 187/582 - (32%)
• Similarity: 281/582 - (48%)
• Gaps: 80/582 - (13%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLIC-LTSIPVAFHKLAGVFLLAKP----DFRCALPFENGSSYD 60
            |..:||...:|:.|.||..:.||:. |..:.||...:....:.|.|    |....||.::.|:..
Mouse     1 MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMADLLPNQSHSNQT 65

  Fly    61 LPTHL----WNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWN 121
            |....    |.|:                  .|||         ....:|:..:.: .|..:||.
Mouse    66 LGKGQAFGDWLLT------------------ANGS---------EIHKHVHFSNSF-TSIASEWF 102

  Fly   122 LVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTF 186
            |:..|.:..:.:.|.|..||.:|.|.||||||::||:.:......:.:||.|..|.:|.|..:..
Mouse   103 LIANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILFAVANGFSPSYEFFAV 167

  Fly   187 ARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALT 251
            .|.:||....|:.|||:|:..|.||......||....:||:||....|:..||:..||.|.:.:.
Mouse   168 TRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAVLVN 232

  Fly   252 LPGLIFMFYYWIIPESARWLLLKGR---KDCAIANMQKAARFNKVEISDEALSELLDEGENSEEK 313
            |.|.:.......||||.|||..:||   .:.|:..:.|..|..|...|       |....|...:
Mouse   233 LQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRKLKCTFS-------LTHPANRSYR 290

  Fly   314 AKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVI 378
            |             ..|..|||.|..|...||::...|.|.|.|||||:.:..:|||::..|..:
Mouse   291 A-------------TGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLAL 342

  Fly   379 SGAVEIPAYIFLLLTLN-RW-GRRSILCGCLVMAGLSLLATVIIPQRMHTLIVA------CAMLG 435
            ||.:|||:|...:..:| || ||:..|...|.:.||:.|..:.:|::..|.:.|      .::||
Mouse   343 SGLIEIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLG 407

  Fly   436 KLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTL 500
            ||.|:|::..|||:::|.:|||:|||.|||.||.:|:.|::|||:..|..:...||.::.|:..|
Mouse   408 KLTISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGATGL 472

  Fly   501 VAGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEA----QPL-KGSGET 557
            .:||||||||||.|.|:|||.:|.:.:.       |...|:|..:.:.    ||| |.|.|:
Mouse   473 TSGLLSLLLPETLNSPLLETFSDLQMYS-------YRRLGEEALSLQTLDPPQPLDKVSSES 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	172/528 (33%)
Slc22a15	NP_001034460.2	MFS_SLC22A15	71..469	CDD:340935	141/445 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..544		6/15 (40%)