Protein Alignment Orct2 and Slc22a29

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_766364.1
• Gene: Slc22a29 / 236293
• MGIID: 3605624
• Length: 551
• Species: Mus musculus
• Alignment Length: 555
• Identity: 155/555 - (27%)
• Similarity: 259/555 - (46%)
• Gaps: 39/555 - (7%)

  Fly     1 MGYDEAIIHLGDFGRYQKI-IYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPF-------ENGS 57
            |.:.|.:..:|..||:|.: |.||..|.:|.|. |.....|..|.|:.||.:|.       :|||
Mouse     1 MSFQELLNQVGSLGRFQILQIVFLFLLNAIVVP-HIGMENFTAAIPNHRCWVPILDNDTASDNGS 64

  Fly    58 SYDLPTHLWNLSYPEN-----ERC-SYYDVDYTEEYLNGSIPR-SSNETKTC-SSYVYDRSKYLN 114
            .......|..:|.|.:     ::| .:....:...:|||:... |..:|:.| ..:|||||.:|:
Mouse    65 RILSQDDLLRISIPLDSNLRLDKCRRFAQPQWHLLHLNGTFSNVSEPDTEPCVDGWVYDRSNFLS 129

  Fly   115 SAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAP 179
            :.||||:|||....:.:.:...||:|:.:|.|:.|.|||::|||.||..:|:...:.......||
Mouse   130 TIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRFGRKFILTCALLQFAITETCVAFAP 194

  Fly   180 EYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWR 244
            .:|.|...|.:.|.:...:.:.::::.:|...|.......:......::|||:.|..|:....|.
Mouse   195 SFFIYCSLRFLAGMSVEPISVNSHLLMLEWTSPKFLAMMAVLSSCAPNIGFMILAGLAFLFRIWH 259

  Fly   245 WLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGEN 309
            .||:.::.|...|:.....:.||||||:|..:....:..::|.|..|.::.|.:...|::.....
Mouse   260 HLQLTMSAPIFFFLILTRWLSESARWLILINKPQKGLKELRKVAHMNGMKNSGDLTMEIVRTSMK 324

  Fly   310 SE-EKAKQKLEDQELDEGPPPSVWDLFCYPNLRRK-TLLIFLDWLVTSGVYYGLSWNTSNLGGN- 371
            :| |.||.|           ||:.|||....||:: .:|.|:....|..: .||:.:..:|..|
Mouse   325 AELEAAKTK-----------PSLRDLFHTSILRKRICVLSFIRLFFTVSI-IGLAVHLQHLSSNI 377

  Fly   372 VLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGK 436
            :||.|:|| |:.|...:.....||..|||......:.:.|:.::..|.:||.|.||.:..|.|..
Mouse   378 ILLQFLIS-ALAILVSVIGPFVLNHIGRRITYLVLMSLRGIFIMIAVFVPQEMQTLRIIMATLAG 441

  Fly   437 LAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLV 501
            ...:...|..::.:.|..||.:|..|||...........::|....:||.:..||.:..|..::.
Mouse   442 GISSLCVGVSHLHTNELLPTTLRATALGVIGFFGNSGLFLSPLFMLVATYYANLPWIFYGGFSIF 506

  Fly   502 AGLLSLLLPETHNKPMLETIAD------GERFGKK 530
            ......|||||.|:|:.::..|      ..|.||:
Mouse   507 NAFTVFLLPETKNQPLPDSTHDVGNDWKESRKGKR 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	149/527 (28%)
Slc22a29	NP_766364.1	MFS_OAT	109..515	CDD:340932	116/418 (28%)