Protein Alignment Orct2 and Slc22a26

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_017173677.1
• Gene: Slc22a26 / 236149
• MGIID: 2385316
• Length: 553
• Species: Mus musculus
• Alignment Length: 574
• Identity: 165/574 - (28%)
• Similarity: 277/574 - (48%)
• Gaps: 55/574 - (9%)

  Fly     1 MGYDEAIIHLGDFGRYQ--KIIYFLIC-LTSIPVAFHKLAGVFLLAKPDFRCALPF-------EN 55
            |.:.:.:..:|..||:|  ::.:.||| :.::|   |.:...|..|....||.:..       .|
Mouse     1 MAFQDLLNLVGSHGRFQILQMAFLLICNVITMP---HVILENFTAANLGHRCWVHIIDNDTNSNN 62

  Fly    56 GSSYDLPTHLWNLSYP-----ENERC------SYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYD 108
            .|.......|..:|.|     ..|:|      .::.:.:...:.|.:.|    :|:.| ..:|||
Mouse    63 NSGILSQDDLLRISIPLDSNLRPEKCRRFVQPQWHLLQFNGSFSNMTEP----DTEPCMDGWVYD 123

  Fly   109 RSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGV 173
            :..:|::.|||||||||...:.:.:..:|::|||.|..|.|.||||:|||.:...:|:...:.|.
Mouse   124 QRTFLSTTVTEWNLVCGSQELNSVAKFIFLIGVLAGHFVGGHLSDKFGRKLLFRCALLQMAITGT 188

  Fly   174 LAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAY 238
            ...:||.:|.|...|.:.|.....:...:.::.:|...|..:.......|.....|.::.|..|:
Mouse   189 CTALAPTFFIYCLLRFLTGLCIIPINTNSVLLMLEWTSPKTQALVTTLSMSSHHFGGLILAGLAF 253

  Fly   239 FVHDWRWLQIALTLPGLIFMFYYWIIP------ESARWLLLKGRKDCAIANMQKAARFNKVEISD 297
            ...:|..||:|:::|  ||:.   :||      ||||||::..:...|:..::|.|..|.::.|:
Mouse   254 AFQNWHHLQLAISVP--IFVL---LIPTSRWLTESARWLIVTNKPQKALQELRKVASKNGIKNSE 313

  Fly   298 EALSELLDEGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLS 362
            :.|         :.|..:..::|:.......||:.|||..||||::..|:.|...:......|::
Mouse   314 DVL---------TMEVVRTIMKDEIAIPRTKPSLRDLFHMPNLRKRLCLLCLLRFLQISPTVGIN 369

  Fly   363 WNTSNLGGNVLLNFVISGAVEIPAYIFLLLTLNRWGRR-SILCGCLVMAGLSLLATVIIPQRMHT 426
            .|..:|.|||.|...::.|..|||.......||..||| |.|..||:. |:.||:.|.:||.|.|
Mouse   370 MNLQHLKGNVFLTQSLTSAFSIPATALGGFLLNYIGRRISQLLPCLLF-GIFLLSIVSVPQEMQT 433

  Fly   427 LIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLP 491
            |:|....|...:....|.:..::|:|..|||:|..|||...:...:...::|.:..|......||
Mouse   434 LLVVLITLAGGSSAMIYNSNVLYSSELMPTVIRATALGVIGICGGVGAALSPLIMILTLYSASLP 498

  Fly   492 LLICGSLTLVAGLLSLLLPETHNKPMLETIAD----GERFGKKTKADVYLETGQ 541
            .:|.|.|:::.|||.|:||||.|:|:.::|.|    .|...:|.:.||.::..|
Mouse   499 WIIYGVLSILGGLLPLILPETKNQPLPDSIQDVECGWESSKQKKEEDVIIKVTQ 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	157/537 (29%)
Slc22a26	XP_017173677.1	MFS	109..506	CDD:475125	125/415 (30%)