Protein Alignment Orct2 and Slc22a19

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_659034.1
• Gene: Slc22a19 / 207151
• MGIID: 2442751
• Length: 551
• Species: Mus musculus
• Alignment Length: 558
• Identity: 174/558 - (31%)
• Similarity: 279/558 - (50%)
• Gaps: 37/558 - (6%)

  Fly     1 MGYDEAIIHLGDFGRYQ--KIIYFLIC-LTSIPVAFHKLAGVFLLAKPDFRCALPF-------EN 55
            |.:.:.||.:|..||:|  .:|:.||| ..|.|   |.|...|..|.|..||.:|.       :|
Mouse     1 MAFQDLIIQIGSLGRFQILHMIFVLICHALSAP---HTLLENFTAAIPSHRCWVPILDNDTASDN 62

  Fly    56 GSSYDLPTHLWNLSYP-----ENERC-SYYDVDYTEEYLNGSIPR-SSNETKTC-SSYVYDRSKY 112
            ||.......|..:|.|     ..::| .|....:...:|||:.|. :..:|:.| ..:|||:|.:
Mouse    63 GSRILSQDDLLRISIPLDSNLRPDKCRRYIQPQWHLLHLNGTFPTVTEPDTEPCVDGWVYDQSTF 127

  Fly   113 LNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGV 177
            |::.||:|:||||...:.:.:..::|.|:.:|.|:.|.||||:|||.|...||:...:.......
Mouse   128 LSTTVTQWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFGRKLIFTCSLLKMAITETCVAF 192

  Fly   178 APEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFS--VGFMLTAVFAYFV 240
            ||.:..|...|.:.|..:|.:...:.::.:|...|  :..|.:..::|.:  ||..|....|:..
Mouse   193 APSFLIYCSLRFLSGIFSSTLRTNSALLILEWTSP--KFQALVMALIFIASGVGQTLLGGLAFAF 255

  Fly   241 HDWRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLD 305
            .:|..||:||::|..:.:.....:.||||||::..:...::..::|||..|:::.|.:||:.
Mouse   256 RNWHHLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNRIKNSGDALTL--- 317

  Fly   306 EGENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGG 370
              |..:...|::||..:    ..||..|||..||||::..|:.....|:.....||..|...|..
Mouse   318 --EVVKTIMKEELEAAQ----TKPSPLDLFRTPNLRKRICLLSFVRFVSVMSLLGLLINIQYLSN 376

  Fly   371 NVLLNFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLG 435
            ||.|...:.|.|.|||.:....::|..|||......:.:.|:|:||.|.:||.|..|.|..:.||
Mouse   377 NVFLLQCLYGVVCIPANVLGNFSMNYMGRRMTQLIFMSVLGISILAVVFLPQEMQILRVFLSTLG 441

  Fly   436 KLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTL 500
            ....:||..:..:.:.|..||::|..|||...:.....|.::|.|..|.|....||.:|.|.|..
Mouse   442 GAISSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMILTTYSASLPWIIYGILPF 506

  Fly   501 VAGLLSLLLPETHNKPMLETIADGE---RFGKKTKADV 535
            :.||::||||||.|:|:.::|.|.|   :..|:.|.||
Mouse   507 LGGLVALLLPETKNQPLPDSIQDIENKRKSSKEAKKDV 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	164/528 (31%)
Slc22a19	NP_659034.1	MFS_OAT	109..516	CDD:340932	128/417 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..551		7/21 (33%)