DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct2 and K09C4.4

DIOPT Version :9

Sequence 1:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_001361998.1	Gene:	K09C4.4 / 187194	WormBaseID:	WBGene00019549	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	564	Identity:	122/564 - (21%)
Similarity:	200/564 - (35%)	Gaps:	163/564 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KIIYFLICLTSIPVAFHKLAGVF-LLAKPDFRCALPFENGSSYDLPTHLWNLSYPENERCSYYDV 81
            :|:|.||||:.:.|....|...| :||.       ...:.:::.|.||              |.:
Worm     8 RILYVLICLSFLDVPCEILTQTFPILAD-------TINDMNNHTLMTH--------------YGI 51

  Fly    82 DYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDSLFMLGVLLGSI 146
                             |.|.:|.     ..:||.:|....|                |.||..|
Worm    52 -----------------TPTVTSI-----SIMNSMITSSETV----------------GTLLSLI 78

  Fly   147 VFGQLSDKYGRKPILF----ASLVIQVLFGVLAGVAPEYFTYTFARLMVGAT-TSGVFLVAYVVA 206
            ....::|..|||.::.    |.|::..|..||:..:.....:..::|..|.. ..|.||.|..:|
Worm    79 FLIPMADTKGRKFLVIYMRSALLILSALCQVLSAYSQSAEFFIMSKLFEGLQHPLGTFLTALFIA 143

  Fly   207 MEMVGPDKR---------LYAGIFVMMFFSVG--FMLTAVFAYFVHDWRWLQIALTLPGLI--FM 258
              ...|||.         :..||..|:...:.  .:|.....:||         ..|..||  |:
Worm   144 --ECAPDKNRGFACTSLVVLVGIVRMIMLPIASPAVLGKADTWFV---------FPLAALISSFL 197

  Fly   259 FYYWI--IPESARWLLLKGRKDCAIANMQ------KAARFNKVEISDEALSELLDEGENSEEKAK 315
            ...|:  :|||.:||:.:.|.:.|..:::      .:..||.|.:|......|..|   |....:
Worm   198 VLIWVCRLPESPKWLVCQNRIEEAKRSIEYYHGNDSSENFNNVLLSIVKEKNLTIE---SHISLR 259

  Fly   316 QKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTS-----GVYYGLSWNTSNLGGN--VL 373
            :.|::..|.||               .|.|..||.:::..     .||..|...::.....  :.
Worm   260 EVLQNDTLREG---------------FKVLFSFLFFILIDSDNALSVYTVLLHKSAGFTTQEAIN 309

  Fly   374 LNFVISGAVEIPAYIFLLLTLNRWGRRSILC---------GCLVMA--------GLSLLATVIIP 421
            :|.:|| .|..|......|.::..|||...|         .||::.        |.:|:..:|
Worm   310 INLIIS-IVFFPTQFIGTLLIDYLGRRPAFCIGGFMIFIKSCLLLLVQFAIYFFGANLITKII-- 371

  Fly   422 QRMHTLIVACAMLGKLAITASYGTVYIFSAEQFP----TVVRNVALGAASMVARISGMMAPFLNF 482
                .:|:||...|..| |.......:|..|.||    |.:..:.|  .:.:|..|.:::.|.
Worm   372 ----DIIIACLGSGPNA-TGMSSLRILFITELFPPSARTSISQIML--FTSLAINSSLLSSFP-- 427

  Fly   483 LATIWKP----LPLLICGSLTLVAGL-LSLLLPETHNKPMLETI 521
            |...|.|    .||:.   ..:..|: |...:|||..:.:.:.|
Worm   428 LLYSWFPPAFFTPLVF---TQMFFGIYLYRYMPETKGRAVCDII 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	121/561 (22%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	94/433 (22%)
K09C4.4	NP_001361998.1	MFS	42..462	CDD:391944	110/515 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910