Protein Alignment Orct2 and Slc22a6

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_032792.2
• Gene: Slc22a6 / 18399
• MGIID: 892001
• Length: 545
• Species: Mus musculus
• Alignment Length: 574
• Identity: 174/574 - (30%)
• Similarity: 281/574 - (48%)
• Gaps: 45/574 - (7%)

  Fly     1 MGYDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHL 65
            |.:::.:..:|..||:|.|...::....:.:|.|.....|..|.|...|..|.....|.|.....
Mouse     1 MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEA 65

  Fly    66 W----NLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTC-SSYVYDRSKYLNSAVTEWNLVCG 125
            |    ....||:  |..:...:     ||:....:..|:.| ..:|||.|.:.::.||||||||.
Mouse    66 WLPLDKQGRPES--CLRFPFPH-----NGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCS 123

  Fly   126 RDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLM 190
            .......:.||||:|||||:::||.|:|:.||:.:|..:.:...:.|..|..||.|..|...||:
Mouse   124 HRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLL 188

  Fly   191 VGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPGL 255
            .|.:.:.:.:....:.||.:....|.|.|..:...:|:|..|.|..||.|..||.||:|:::|..
Mouse   189 SGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFF 253

  Fly   256 IFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAKQKLE- 319
            :...|.|...|||||....||.|..:..:|:.||.|                ...||.||..:|
Mouse   254 VAFIYSWFFIESARWYSSSGRLDLTLRALQRVARIN----------------GKQEEGAKLSIEV 302

  Fly   320 -------DQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFV 377
                   :..|::| ..|..:|...|.|||..|.:.:.|..||..||||..:....|.::.|..|
Mouse   303 LQTSLQKELTLNKG-QASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQV 366

  Fly   378 ISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLI-VACAMLGKLAITA 441
            |.|||::||.....|.:|..|||......|::||:.:|...||| |.||:| .:.|:|||..:.:
Mouse   367 IFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIP-RGHTIIRTSLAVLGKGCLAS 430

  Fly   442 SYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLS 506
            |:..:::::.|.:||::|...||..|.:||:..:::|.::..|..:..:||.|.|::.:.|..::
Mouse   431 SFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVT 495

  Fly   507 LLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEAQPLK-GSGETNG 559
            .|||||..:|:.:|:.|.:...:..:....||..:::     .||: .:.|.||
Mouse   496 ALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQM-----IPLQVSTQEKNG 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	164/522 (31%)
		MFS	127..503	CDD:119392	123/384 (32%)
Slc22a6	NP_032792.2	2A0119	11..509	CDD:273328	164/522 (31%)
		MFS	129..499	CDD:119392	125/387 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	515..545		7/35 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.980