DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Orct2 and suex-2

DIOPT Version :9

Sequence 1:	NP_001262907.1	Gene:	Orct2 / 42890	FlyBaseID:	FBgn0086365	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_501556.2	Gene:	suex-2 / 183742	WormBaseID:	WBGene00008271	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	538	Identity:	132/538 - (24%)
Similarity:	209/538 - (38%)	Gaps:	134/538 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 NLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSK-YLNSAVTEWNLVC----GR 126
            |..|....:| ..|.|:..:.|   .|  .|.|:..|..:.|.|: :..||..|:...|    |.
Worm    43 NFCYKLQSKC-LMDYDHNAQNL---CP--VNMTENASKCIADHSRLFFRSAQFEYQQDCTGLNGF 101

  Fly   127 DFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMV 191
            ....||     .:|.|||:|..|.|:|||||:.|..:||:..:...||:......:::...|:::
Worm   102 SLSTAT-----FIGTLLGNIALGFLADKYGRRTIYLSSLLFGIPCVVLSAAITNIYSFYIFRILI 161

  Fly   192 GATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQI------AL 250
            |.:.||...|.:..|.||:.|::||  .|.....:....|:....||...:|:....      .|
Worm   162 GISVSGTLTVGWTYATEMISPNRRL--RILAFSNWPNARMIQVGLAYISQEWKTATYICAAVSCL 224

  Fly   251 TLPGLIFMFYYWIIPESARWLLLKGR-KDCAIA--NMQKAARFNKVEISDEALSELLDEGENSEE 312
            :||.||:      :|||..||..|.: |:.:.|  .::|..:|.              ..|:|..
Worm   225 SLPILIY------LPESPIWLDQKQKYKNASKARKRLRKIGKFY--------------SNEHSTV 269

  Fly   313 KAKQKLEDQELDEGPPPSVWDLFCYPNLRRK-TLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNF 376
            .|.:|..       |...:.|    |.||.. .::||:.:.|...||. ...|.:::..|:.|..
Worm   270 VANRKFT-------PTRILKD----PKLRNSFFMIIFMYFYVGLAVYI-TDLNGADMTKNLYLGQ 322

  Fly   377 VISGAVEIPAYIFLLLT---LNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAML---G 435
            .:||.|...|...:.:|   |...|||.:.   |:...:::|.        :..|:.|..|   |
Worm   323 FLSGLVLSIAQFIIGMTEPYLTGLGRRVLF---LIAQFIAMLC--------YICILICLYLNWKG 376

  Fly   436 KL----AITASYGT-------VYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKP 489
            ..    |.|.:|.|       .|:...|..||.||..|...|::..:|.       ..|||:.||
Worm   377 SFLYLSAYTLAYATQSLCLEAAYLSLVELMPTDVRATAGSTANICMKIG-------TILATLTKP 434

  Fly   490 L-----PLLICGSLTL-VAGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEA 548
            |     |.|...:|:: ..|::.:...                          ||..:|
Worm   435 LKFAYEPSLFFINLSICTIGMILVFFK--------------------------LEESRE------ 467

  Fly   549 QPLKGSGETNGSTIANGH 566
            ..:|..|:|| ..||:.|
Worm   468 ADMKMIGQTN-DNIASAH 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	122/490 (25%)
Orct2	NP_001262907.1	MFS	127..503	CDD:119392	104/408 (25%)
suex-2	NP_501556.2	MFS	108..460	CDD:391944	103/403 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910