Protein Alignment Orct2 and Slc22a13

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_598741.2
• Gene: Slc22a13 / 102570
• MGIID: 2143107
• Length: 551
• Species: Mus musculus
• Alignment Length: 582
• Identity: 182/582 - (31%)
• Similarity: 294/582 - (50%)
• Gaps: 62/582 - (10%)

  Fly     3 YDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWN 67
            :.:.:..:|||||:|..:..|:.:.:...||.....||::......|::.:       :..|.:|
Mouse     4 FAQVMAEVGDFGRFQVRLTILMGIPNFLAAFFIFGQVFMVLDEAHHCSVSW-------VKNHTFN 61

  Fly    68 LSYPEN-------------ERCSYYDVDYTEEYLNGSIPRSSNETKTCSS---YVYDRSKYLNSA 116
            ||..|.             |.|..:........|...:....|||:.|.|   |..:|.:.|..
Mouse    62 LSAAEQLAISIPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQACDSGWDYPENRPQSLKK- 125

  Fly   117 VTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEY 181
              |::|||.|..:..||.|:||.|:|:|::|||.:.|..||:|    ||::|||...:..:|..:
Mouse   126 --EFDLVCDRKNLKKTSQSVFMAGLLVGALVFGPVCDWIGRRP----SLLMQVLLSGITSMATAF 184

  Fly   182 FT----YTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHD 242
            .:    |...|.::....:|..|...|:..|.|||..|..|.:......::|.|:.|..||.|.:
Mouse   185 VSSFELYLALRFVLATANAGFLLSTNVLISEWVGPSWRTQAVVLAQSNVALGQMVLAGLAYGVRN 249

  Fly   243 WRWLQIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEG 307
            ||.|||..|.|.|:..||:|::|||.||||.:||.:.|...:||||..|...:|.|.|::|:.|
Mouse   250 WRLLQITGTAPVLLLFFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLSPELLNQLVPE- 313

  Fly   308 ENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNV 372
                            ..||..:..|||.:|:||:.||::...|.|.|.|||.||:...:.|.::
Mouse   314 ----------------KTGPSGNALDLFRHPHLRKVTLILIAVWFVDSLVYYSLSFQVGDFGLDI 362

  Fly   373 LLNFVISGAVEIPAYIFLLLTLNRWGRR-SILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGK 436
            .:..:|.||||:|.....:|.:.:.||: |.|| .|.:||:..:..:.||..:.|::...|::||
Mouse   363 YVTQLIFGAVEMPGRFLSVLMMEKLGRKWSQLC-TLTLAGIMYIIIIFIPGDLPTVVTVLAVVGK 426

  Fly   437 LAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLV 501
            .|..|::...|:::||.|||::|...:|..|:.:|:.|::.|.:..|....:.:|::|.|||.:.
Mouse   427 FASAAAFTISYVYTAELFPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHQAIPMVIFGSLPIG 491

  Fly   502 AGLLSLLLPETHNKPMLETIADGERFGKKTKADVYLETGQELRAPEAQPLKGSGETNGSTIA 563
            ||||..|||||..:.:.:|:.|.|:         .|..|....||:.|.::..|.|:...:|
Mouse   492 AGLLCALLPETRGQTLKDTLQDLEQ---------GLPAGSHKTAPQRQDMEALGRTSSVRVA 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	171/529 (32%)
Slc22a13	NP_598741.2	2A0119	12..510	CDD:273328	171/529 (32%)