Protein Alignment Orct2 and slc22a2

DIOPT Version :10

• Sequence 1: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_002933908.1
• Gene: slc22a2 / 100487774
• XenbaseID: XB-GENE-965056
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 181/562 - (32%)
• Similarity: 285/562 - (50%)
• Gaps: 47/562 - (8%)

  Fly     3 YDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHL-- 65
            :||.:.|:|:|..:||.|:.|:|..|:..:...:..|||...||:||.       |..:|...
 Frog     4 FDELLEHIGEFDAFQKQIFILLCFISVVFSPIYVGIVFLGFVPDYRCV-------SAGIPEPSNE 61

  Fly    66 --WNLSY--PEN-------ERCSYYDVDYTEEYL---NGSIPRSSNETKTCSSYVYDRSKYLNSA 116
              |.|:|  |..       .:|..||||:....|   |.|:..:|....|.....:|.:...:|.
 Frog    62 CEWTLNYTGPNGSTDSLYMSQCYQYDVDWNSTSLNCTNSSLNITSKLPITNCKDGWDYNTTGSSL 126

  Fly   117 VTEWNLVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEY 181
            |||:|||||..:......|...:|..:|.::.|.::|::||||.|.:|::|..:||:|...||.|
 Frog   127 VTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIADRFGRKPFLISSILITGIFGILMAFAPNY 191

  Fly   182 FTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWL 246
            ......|.:.|..:.|.:|..|::..|.||.:.|...||.....|:||.:|.:..||.:..||||
 Frog   192 PLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAYVLPHWRWL 256

  Fly   247 QIALTLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISD--EALSELLDEGEN 309
            |:.:|:|...|:.|||.:|||.|||:.:.||..|.|.:...|:.|...:.|  |:|:
 Frog   257 QMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVPDFLESLT-------- 313

  Fly   310 SEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLL 374
                     .|:|..|...||..||...|.:|:.||::...|...:.||.|...:..:...|:..
 Frog   314 ---------ADEEAGEKQVPSFLDLVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIYF 369

  Fly   375 NFVISGAVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAI 439
            :|.||..||.|:.|.:::|::|.|||.....|.::.|::.|.|..||.....||:..:.:.::.|
 Frog   370 DFFISALVEFPSAILIIVTVDRVGRRYPWLVCCIITGITCLITAFIPHGYSWLIITLSCVSRMGI 434

  Fly   440 TASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNF-LATIWKPLPLLICGSLTLVAG 503
            |.||..|.:.:||.:||.:||:.:...|.:..:.|::.||:.: ||.||:.|||::...|..|:|
 Frog   435 TVSYEMVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIVYRLAAIWQELPLIVFAVLATVSG 499

  Fly   504 LLSLLLPETHNKPMLETIADGERFGKKTK----ADVYLETGQ 541
            :|...||||..:.:.|||.:.|...|:.|    |..|||..:
 Frog   500 ILVYFLPETKGRALPETIEEAENLHKQVKTTKLATTYLEVSK 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	168/527 (32%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	168/527 (32%)