Protein Alignment Orct2 and slc22a5

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_002934410.2
• Gene: slc22a5 / 100486941
• XenbaseID: XB-GENE-484416
• Length: 550
• Species: Xenopus tropicalis
• Alignment Length: 551
• Identity: 195/551 - (35%)
• Similarity: 313/551 - (56%)
• Gaps: 36/551 - (6%)

  Fly     3 YDEAIIHLGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWN 67
            ||:|...||::|.:|..::||:..:.||..|..|:.|||.|.|:.||.:|    .|.:|.....|
 Frog     4 YDQATAFLGEWGPFQVSVFFLLSASIIPNGFTGLSAVFLAATPEHRCHIP----ESANLSAAWRN 64

  Fly    68 LSYP----ENERCSYYDVDYTEEY-----LNG-SIPRSSNETKTC-SSYVYDRSKYLNSAVTEWN 121
            .|.|    ::.:|..|.:.....|     |.| .:..:..|.:.| ..:.|.:|.||::.|||||
 Frog    65 ASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWN 129

  Fly   122 LVCGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTF 186
            |||..|:....:.|||.:|||:||.|.||:||::|||.:|||::.:|..|.::...:..:..:|.
 Frog   130 LVCENDWKGPLTTSLFFVGVLIGSFVSGQMSDRFGRKKVLFATMAVQTGFSIIQVFSVNWEMFTA 194

  Fly   187 ARLMVGATTSGVFLVAYVVAMEMVGPDKR-LYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIAL 250
            ..::||......::.|:::..|::....| :::.:.|.:|:::|:||..:||||:.|||.|.:||
 Frog   195 LFIIVGMGQISNYVAAFILGAEILDKSVRIIFSTLGVCIFYAIGYMLLPLFAYFIRDWRTLLLAL 259

  Fly   251 TLPGLIFMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKAK 315
            |:|||..:..:||||||.|||:.:||...|...::|||:.|.:...|...        |..|..:
 Frog   260 TIPGLFCIPLWWIIPESPRWLISQGRFQEAEDIIRKAAKKNGITPPDSIF--------NFTELQE 316

  Fly   316 QKLEDQELDEGPPPSVWDLFCYPNLRRKTLLIFLDWLVTSGVYYGLSWNTSNLGGNVLLNFVISG 380
            ||    ||.. ...:..||....|:|..|.|..|.|::.|..|:|||.||.||.|:..:|..:|.
 Frog   317 QK----ELTH-KSHTFLDLLKTRNIRIITFLSILLWMIISVGYFGLSLNTPNLHGDPYVNCFLSA 376

  Fly   381 AVEIPAYIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITASYGT 445
            .:|:|||:...|.|..:.||......||:.|:.||...::||.:..|.:...||||..||:::..
 Frog   377 IIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLLFIQLVPQELGILSIVLVMLGKFGITSAFSM 441

  Fly   446 VYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWKPLPLLICGSLTLVAGLLSLLLP 510
            ||:::||.:||||||:.:||:||.:|:..:::|:..:|....:.||.::.||||::.|:.:|.||
 Frog   442 VYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLCLP 506

  Fly   511 ETHNKPMLETIAD-----GERF--GKKTKAD 534
            |:|..|:.:||.:     |.|:  ||:.|.|
 Frog   507 ESHGMPLPDTIEEMLRVKGFRYKAGKRLKKD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	183/520 (35%)
		MFS	127..503	CDD:119392	135/376 (36%)
slc22a5	XP_002934410.2	2A0119	12..516	CDD:273328	183/520 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	348	1.000	Inparanoid score	I2245
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	1	1.000	-	-		mtm14089
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.180