Protein Alignment Orct2 and sv2a

DIOPT Version :9

• Sequence 1: NP_001262907.1
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 111/586 - (18%)
• Similarity: 194/586 - (33%)
• Gaps: 200/586 - (34%)

  Fly   119 EWNL--VCGRDFMA-------------------ATSDS-------LFMLGVLLGSIVFGQLSDKY 155
            :|.|  |.|...||                   ..|||       :..||:::|:.::|.::|:.
 Frog   152 QWTLYFVLGLALMADGVEIFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGMADRI 216

  Fly   156 GRKPILFASLVIQVLFGVLAGVAPEYFTYTFARLMVGATTSGVFLVAYVVAMEMVGPDKRLYAGI 220
            ||:..|..||.:..:|...:.....|.|:.|.||:.|....|...:.:....|.:..:||.....
 Frog   217 GRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLS 281

  Fly   221 FVMMFFSVGFMLTAVF----------------AYFVHDWRWLQIALTLPGLIFMFYYWIIPESAR 269
            ::.||:.:|.:..:..                ||..|.||...:....|.:..:.....:|||.|
 Frog   282 WLCMFWMIGGIYASAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTMPESPR 346

  Fly   270 WLLLKGRKDCA--------IANMQKAAR----FNKVEI----SDEALSELLDEGENSEEKAKQKL 318
            :.|..|:.|.|        ..||:....    |:..:|    .|:.|.|:..:......:...||
 Frog   347 FFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTQIKTIKQDDELVEIQSDTGALHRRWMIKL 411

  Fly   319 ED--QELDEGPPPSVWDLF--CY-PNLRRKTLLIFLDWLVTSGVYYGLS-W------NTSNLG-- 369
            .:  ||        ||..|  |: |..||.||::...|...|..||||: |      :..|:.
 Frog   412 LNLSQE--------VWANFHQCFAPEYRRITLMMMAVWFTMSFSYYGLTVWFPDMIKHLQNIDYA 468

  Fly   370 -----------GNVLLNFVISGAVE---------------------------------------- 383
                       .|...||.:...|.
 Frog   469 SRTKYFHNESVNNFNFNFTLENQVHRKGEYHNDKFIGLKLKSVIFEDSLFTDCYFEDITSSNTFF 533

  Fly   384 --------------------------------------------------------------IPA 386
                                                                          :|.
 Frog   534 KNCSFIRTMFYNTDLFDYKFINSKFTNSTFLHSKEGCQLDFSDDINNAYMIYFVSFLGTLAVLPG 598

  Fly   387 YIFLLLTLNRWGRRSILCGCLVMAGLSLLATVIIPQRMHTLIVACAMLGKLAITASYGTVYIFSA 451
            .|...|.:::.||..:|.|..||:.:|.. .:........:|....:.|.::| ||:..:.:.:.
 Frog   599 NIVSALLMDKIGRLRMLAGSSVMSCISCF-FLFFGNSESAMIALLCLFGGVSI-ASWNALDVLTV 661

  Fly   452 EQFPTVVRNVALGAASMVARISGMM--APFLNFLATIWKPLPLLICGSLTLVAGLLSLLLPETHN 514
            |.:|:..|..|.|..:.:.:::.::  :.|.:|:. :.|.:|:|:..:...|...|:|.||||..
 Frog   662 ELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVG-VAKAVPILLASAALAVGSFLALKLPETRG 725

  Fly   515 K 515
            :
 Frog   726 Q 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orct2	NP_001262907.1	2A0119	11..520	CDD:273328	111/586 (19%)
		MFS	127..503	CDD:119392	101/562 (18%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	111/586 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940