Protein Alignment jar and XIC

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_172349.2
• Gene: XIC / 837394
• AraportID: AT1G08730
• Length: 1538
• Species: Arabidopsis thaliana
• Alignment Length: 1134
• Identity: 389/1134 - (34%)
• Similarity: 554/1134 - (48%)
• Gaps: 178/1134 - (15%)

  Fly     8 VWVRDAAEGYIQGRITEIGAKEFEVTPTDRK---------YPKRTCHFDDIHSSCDGPQDHDDNC 63
            ||..|....:|.|.:.:|..:|..:..|..|         |||      |:.:...|.   ||..
plant    21 VWFEDPEVAWIDGEVEKINGQEVVIQATTGKKVTAKLSKIYPK------DVEAPAGGV---DDMT 76

  Fly    64 ELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVF 128
            :|..|:|...|.|||.||..::||||..|||||:||::.:..:|....:::|.|..||||.||||
plant    77 KLSYLHEPGVLQNLKIRYELNEIYTYTGNILIAINPFQRLPHIYDAHMMQQYKGAPLGELSPHVF 141

  Fly   129 AIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSA----GPIETKILDANPVL 189
            |:||.|.|.|.....|.||:|||||||||||:||.|::||.|....|    ..:|.::|::||||
plant   142 AVADVAYRAMINEGKSNSILVSGESGAGKTETTKMLMRYLAYLGGRAVTEGRTVEQQVLESNPVL 206

  Fly   190 EAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAG 254
            ||||||||.|||||||||||:|:.:|.:.::.|..|..||||:||:|..|..|||||.||:|.|
plant   207 EAFGNAKTVRNNNSSRFGKFVEIQFDKQGRISGAAIRTYLLERSRVCQISDPERNYHCFYLLCA- 270

  Fly   255 APQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNL 319
            |||:..:|..||.|..:.||:                   :||..:..|      |.|...:...
plant   271 APQEEIEKYKLGHPKTFHYLN-------------------QSKCFELVG------ISDAHDYLAT 310

  Fly   320 DKALGRLGLSDTEKLGIYSLVAAVLHLGNIAF-------EEIPDDVRGGCQVSEASEQSLTITSG 377
            .:|:..:|:|:.|:..|:.:|||:||:|||.|       ..:|.|        |.|:..|...:.
plant   311 RRAMDIVGISEKEQEAIFRVVAAILHIGNIDFTKGKEVDSSVPKD--------EKSKFHLKTAAE 367

  Fly   378 LLGVDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQS 442
            ||..|...|..||..|||.:     ...||...|....|..:||.|||.:||||||.:|..||:|
plant   368 LLMCDLKALEDALCKRVMIT-----PEEVIKRSLDPQSAVTSRDGLAKTVYSRLFDWLVDKINKS 427

  Fly   443 IPFQA-SNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEI 506
            |...| |...||||||.|||.|..|||||||||:.|||||:.||.::.|.|||.|.:|.::...|
plant   428 IGQDANSRSLIGVLDIYGFESFKTNSFEQFCINFTNEKLQQHFNQHVFKMEQEEYTKEAIDWSYI 492

  Fly   507 TFTDNQDIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTL 571
            .|.||||:::|||.|..||..||||....||.::..|..::::::..|.|...|:.||
plant   493 EFVDNQDVLDLIEKKPGGIVALLDEACMFPKSTHETFANKLYQTFKTHKRFIKPKLSR------- 550

  Fly   572 RDEEGFLVRHFAGAVCYNTEQFIEKNNDAL---HASLEGLVQECDNPLLQTLFPS-GSSTSVRGK 632
               ..|.|.|:||.|.|.:|.|::||.|.:   |..|.| ..:|  |.:..|||. ...||...|
plant   551 ---TDFAVAHYAGEVLYQSELFLDKNKDYVIPEHQDLLG-ASKC--PFVVGLFPPLPEETSKSSK 609

  Fly   633 LNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELME 697
              |.|:||:||.||.:|||.|.....::|||:|||:.:....||....:.||:|.|.:..:.:..
plant   610 --FSSIGSRFKLQLQQLMETLNCTEPHYIRCVKPNNLLKPAIFENVNIMQQLRCGGVLEAIRISC 672

  Fly   698 HGYPSRVLFADLYSMYKSVLPPELV-SLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEF 761
            .|||:|..|.:..:.:..:.|..|. :...:..|:.:..  |:..|.::.|.||||.|.|:..|.
plant   673 AGYPTRKPFFEFINRFGLLSPAALEGNFDEKVACQKILD--NMGLKGYQIGKTKVFLRAGQMAEL 735

  Fly   762 DRIMRSDPENMLAIVAK----------VKKWLIRSRWVKSALGALC-----------------VI 799
            | ..|::   :|:..||          .:|..|..|....:|.|:|                 .:
plant   736 D-ARRAE---VLSSAAKKIQRRIRTHQAQKRFIVLRKATISLQAICRGRLSCKHYDNLRREAAAV 796

  Fly   800 KLR-------NRIIYRNKCV--LIAQRIARGFLARKQHRPRYQ-GIGKINKIRTNTLKTIEIASG 854
            |::       :|..|:...|  |:.|...|...||||.|.|.| ....|.:.:....:.|.....
plant   797 KIQKNGRRHYSRKSYKKLHVASLVVQTGLRAMAARKQFRFRKQTKAATIVQAQWRCHRAISYYKK 861

  Fly   855 LKMGREEIISGVNDIYRQIDDAIKKIKMNPRIT--QREMDSMYTVVMANMNKLTVDLNTKLKEQQ 917
            ||.|  .::|......|.....::|:||..|.|  .:|...|   :...:.:||..:..:.:.:.
plant   862 LKNG--VVLSQTRWRGRLAKRELRKLKMAARETGALKEAKDM---LEKKVEELTYRVQLEKRSRG 921

  Fly   918 QAEEQERLRKIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAA-EAQRLRQEE----ED 977
            ..||    .|.||.|:.:   ...||.|::.:..|..|..|.|..:||| ||..:.:|.    ||
plant   922 DLEE----AKTQEILKLK---SSFEEMRKKVDETNALLLKEREAAKKAAEEAPPVIKETQILVED 979

  Fly   978 RRAALALQEQL---------EKEAKDDA-------------KYRQQLEQERRDHEL--ALRLANE 1018
            .:....:.|:|         ||:..|||             |.::..|.|::..:|  :|....|
plant   980 TKKIELMTEELESVKVTLENEKQRADDAVRKFEEAQESLEDKKKKLEETEKKGQQLQESLTRMEE 1044

  Fly  1019 SNGQVEDSPPVIRNGVNDASPMGPNKLIS 1047
            ....:|....|:|   ..|..|.|||.:|
plant  1045 KCSNLESENKVLR---QQAVSMAPNKFLS 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670	12/49 (24%)
		MYSc_Myo6	71..754	CDD:276833	283/699 (40%)
		CBD_MYO6-like	765..913	CDD:409646	40/186 (22%)
		ERM_helical	<954..1020	CDD:466641	24/94 (26%)
		MYO6_MIU_linker	1002..1093	CDD:480843	14/48 (29%)
		MyUb_Myo6	1076..1116	CDD:439319
		Myosin-VI_CBD	1160..1246	CDD:465157
XIC	NP_172349.2	Myosin_N	16..60	CDD:460670	9/38 (24%)
		MYSc_Myo11	84..728	CDD:276835	283/699 (40%)
		DUF5401	<747..1058	CDD:375164	75/325 (23%)
		MyosinXI_CBD	1119..1504	CDD:271259