DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jar and XI-I

DIOPT Version :9

Sequence 1:	NP_001014650.2	Gene:	jar / 42889	FlyBaseID:	FBgn0011225	Length:	1268	Species:	Drosophila melanogaster
Sequence 2:	NP_001328260.1	Gene:	XI-I / 829456	AraportID:	AT4G33200	Length:	1523	Species:	Arabidopsis thaliana

Alignment Length:	1272	Identity:	364/1272 - (28%)
Similarity:	571/1272 - (44%)	Gaps:	265/1272 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEDTQLVWVRDAAEGYIQGRI---TEIGAKEFEVTPTD--RKYPKRTCHFDDIHSSCDGPQDHDD 61
            :||..|.|:..........::   |..|.|.| |:|..  |:.|.     |:.|:..      ||
plant    19 VEDKDLAWIAADVLDSFDNKLHVETSTGKKVF-VSPEKLFRRDPD-----DEEHNGV------DD 71

  Fly    62 NCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPH 126
            ..:|..|:||..|.||:.||..:.||||..:|||||||::::..||....:::|.|...|||.||
plant    72 MTKLTYLHEAGVLYNLQRRYALNDIYTYTGSILIAVNPFKKLPHLYNGHMMEQYMGAPFGELSPH 136

  Fly   127 VFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCY----SHDSAGPIETKILDANP 187
            |||::|.|.|.|.....||||:|||||||||||:||.:::||.:    :.|....:|.::|::||
plant   137 VFAVSDVAYRAMIDDSRSQSILVSGESGAGKTETTKLIMQYLTFVGGRATDDDRSVEQQVLESNP 201

  Fly   188 VLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLL 252
            :|||||||||.||:||||||||:|:.:|...::.|..|..||||:||:...:..|||||.||.|.
plant   202 LLEAFGNAKTVRNDNSSRFGKFVEIQFDTNGRISGAAIRTYLLERSRVVRITDPERNYHCFYQLC 266

  Fly   253 AGAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFH 317
            |....  .:|..|..|..:.||:                   :||.::.:|      :...:.:.
plant   267 ASGND--AEKYKLSNPRQFHYLN-------------------QSKTYELEG------VSSAEEYK 304

  Fly   318 NLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVD 382
            |..:|:..:|:|..|:.||:..:||:|||||:.|....:......:..| |...|.:.:.|...|
plant   305 NTRRAMDIVGISQDEQEGIFRTLAAILHLGNVEFSSGREHDSSVVKDPE-SRHHLQMAADLFKCD 368

  Fly   383 QTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSI---P 444
            ...|..:|.:|.:.::.|     :|:..|....|..:||.|||.:|:.|||.:|..||:|:   |
plant   369 ANLLLASLCTRSILTREG-----IIIKALDPNAAVTSRDTLAKTVYAHLFDWLVDKINKSVGQDP 428

  Fly   445 FQASNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFT 509
              .|.|.||||||.|||.|..|||||||||:.|||||:.||:::.|.||:.|::|.:|...|.|.
plant   429 --ESRFQIGVLDIYGFECFKNNSFEQFCINFANEKLQQHFNEHVFKMEQDEYRKEEINWSYIEFI 491

  Fly   510 DNQDIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDE 574
            ||||:::|||.|..|:..||||....|:.::..|:.::.:::..|.||..|:.|          |
plant   492 DNQDVLDLIEKKPIGVIALLDEACMFPRSTHESFSMKLFQNFRFHPRLEKPKFS----------E 546

  Fly   575 EGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPSGSSTSVRGKLNFISVG 639
            ..|.:.|:||.|.|.||.|::||.|........|:.....|.:..:|||....|.|....|.||.
plant   547 TDFTLSHYAGKVTYQTEAFLDKNRDYTIVEHCNLLSSSKCPFVAGIFPSAPEESTRSSYKFSSVS 611

  Fly   640 SKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRV 704
            |:||.||..|||.|.:...:::||:||||....::||....|.||:|.|.:..:.:...|||:|.
plant   612 SRFKQQLQALMETLSKTEPHYVRCVKPNSLNRPQKFESLSVLHQLRCGGVLEAVRISLAGYPTRR 676

  Fly   705 LFADLYSMYKSVLPPELV--SLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFD----- 762
            .::|....: .:|.||.:  |...:...|.:...|.|.  :::.|.||||.|.|:....|
plant   677 NYSDFVDRF-GLLAPEFMDESNDEQALTEKILSKLGLG--NYQLGRTKVFLRAGQIGILDSRRAE 738

  Fly   763 ----------RIMRS--DPENMLA-------------------------------IVAK-VKKWL 783
                      |.:|:  ..:|.::                               :|.| |::||
plant   739 VLDASARLIQRRLRTFVTHQNFISARASAISIQAYCRGCLSRNAYATRRNAAAAVLVQKHVRRWL 803

  Fly   784 IRSRWVKSALGAL----C---------------------------VIKLRNRIIYRNKCVLIAQR 817
            .|..:||....|:    |                           :.|.|:...:|...::..|.
plant   804 SRCAFVKLVSAAIVLQSCIRADSTRLKFSHQKEHRAASLIQAHWRIHKFRSAFRHRQSSIIAIQC 868

  Fly   818 IARGFLARKQHRPRYQ---GIGKINKIRTNTLKTIE-------IASGLKMGREEI---------- 862
            ..|..||:::.|...|   ..|.:...:|...|.:|       :...|:...||.
plant   869 RWRQKLAKREFRKLKQVANEAGALRLAKTKLEKRLEDLEWRLQLEKRLRTSGEEAKSSEISKLQK 933

  Fly   863 -------------ISGVND------IYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVD 908
                         ::.:|:      :.:|:|.::|:    ....:||::.|  |.:...|.|..:
plant   934 TLESFSLKLDAARLATINECNKNAVLEKQLDISMKE----KSAVERELNGM--VELKKDNALLKN 992

  Fly   909 LNTKLKEQQQAEEQERL-------RKIQEALEAERAAKEAEEQRQREEIENKRLKAEMET---RR 963
            ....|:::.:..|:|.|       ..:|:..|||:...|.:...|..|.:...|:.|.:.   :.
plant   993 SMNSLEKKNRVLEKELLNAKTNCNNTLQKLKEAEKRCSELQTSVQSLEEKLSHLENENQVLMQKT 1057

  Fly   964 KAAEAQRLRQ-------------EEEDRRAALALQEQLEKEAKDDAKYRQQLEQERR-------- 1007
            .....:|:.|             .:.|||:..    :....:|....:...|.:.||
plant  1058 LITSPERIGQILGEQKHSSAVVPAQNDRRSVF----ETPTPSKHIMPFSHSLSESRRSKLTAERN 1118

  Fly  1008 --DHELALRLANESNGQVEDSP------------------------PVIRNGVNDASPMGPNK-- 1044
              ::||..|...|:.|..:|.|                        .:|..|:|:|...|...
plant  1119 LENYELLSRCIKENLGFNDDKPLAACVIYKCLLHWRAFESESTAIFNIIIEGINEALKGGDENGV 1183

  Fly  1045 ---LISFSQVVSNIASRYLNKSENVRAQQQALGKQKY 1078
               .:|.:..:..:..|.|..:..:.|..|..|:..|
plant  1184 LPYWLSNASALLCLLQRNLRSNSFLNASAQRSGRAAY 1220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..45	CDD:280832	10/42 (24%)
		Myosin_head	59..754	CDD:278492	267/703 (38%)
		MYSc_Myo6	71..754	CDD:276833	262/691 (38%)
		RILP-like	<968..1015	CDD:304877	11/69 (16%)
		Myosin-VI_CBD	1160..1246	CDD:293129
XI-I	NP_001328260.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910