DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jar and XIJ

DIOPT Version :9

Sequence 1:	NP_001014650.2	Gene:	jar / 42889	FlyBaseID:	FBgn0011225	Length:	1268	Species:	Drosophila melanogaster
Sequence 2:	NP_001319790.1	Gene:	XIJ / 824985	AraportID:	AT3G58160	Length:	1242	Species:	Arabidopsis thaliana

Alignment Length:	1260	Identity:	385/1260 - (30%)
Similarity:	595/1260 - (47%)	Gaps:	238/1260 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VWVRDAAEGYIQGRITEIGAKEFEVTPTD---------RKYPKRTCHFDDIHSSCDGPQDH-DDN 62
            |||.|....:|.|.:..|..:|.|:...|         |.|||.|          :.|.:. :|.
plant    11 VWVEDPERAWIDGVVLNIKGEEAEIKTNDGRDVIANLSRLYPKDT----------EAPSEGVEDM 65

  Fly    63 CELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHV 127
            ..|..|:|...||||.|||..::||||..||||||||::.:..||..:.::||......||.|||
plant    66 TRLSYLHEPAVLDNLATRYELNEIYTYTGNILIAVNPFQGLPHLYDAEVMEKYKEAYFKELNPHV 130

  Fly   128 FAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCY--SHDS--AGPIETKILDANPV 188
            |||...|.|:|.....::.|:||||||:||||:||.|::||.|  .|.:  ...:|.::|::|||
plant   131 FAIGGIAYREMINEGRNKCILVSGESGSGKTETTKMLMRYLAYFGGHTAVEGRTVENQVLESNPV 195

  Fly   189 LEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLA 253
            |||||||||.:||||||||||:|:.:|...::.|..|..||||:||:|..|..|||||.||:|.|
plant   196 LEAFGNAKTVKNNNSSRFGKFVEIQFDDVGRISGAAIRTYLLERSRVCQVSDPERNYHCFYLLCA 260

  Fly   254 GAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHN 318
            ..|:.: ::..||.|..:|||:..:.|..:.                         ::|.:.:..
plant   261 APPEDV-ERFKLGDPKSFRYLNQSSCYKLDG-------------------------VNDAEEYLA 299

  Fly   319 LDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVDQ 383
            ..:|:..:|:|:.|:..|:.:||::||||||.|.: .:|........|.|...|.:||.||..|.
plant   300 TRRAMDVVGISEKEQDAIFRVVASILHLGNIEFSK-GEDADSSSVKDEQSMFHLQMTSELLMCDP 363

  Fly   384 TELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPFQA- 447
            ..|..||..|:|.:     ...||...|....|:.:||.|||.|||||||.:|..||.||...:
plant   364 HSLEDALCKRMMVT-----PEEVIKRSLDPLGAAVSRDGLAKTIYSRLFDWLVNKINISIGQDSH 423

  Fly   448 SNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQ 512
            |...||||||.|||.|..||||||||||.|||||:.||.::.|.||..|::|.::...:.|.||:
plant   424 SRRLIGVLDIYGFESFKTNSFEQFCINYTNEKLQQHFNQHVFKMEQGEYQKEEIDWSYVEFVDNK 488

  Fly   513 DIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDEEGF 577
            |:::|||.|..||..||||...|||.:...|:.:::.::.:|.|...|:.:|          ..|
plant   489 DVVDLIEKKPGGIIALLDEACMLPKSTPETFSEKLYHTFKDHKRFMKPKLTR----------SDF 543

  Fly   578 LVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPSGSSTSVRGKLNFISVGSKF 642
            .:.|:||.|.|.::||::||.|.:.|..:.|:.......:..|||.....|.:.|  |.|:|::|
plant   544 TLVHYAGDVQYQSDQFLDKNKDYVVAEHQDLLNASKCSFVSGLFPPLPKESSKSK--FSSIGARF 606

  Fly   643 KTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFA 707
            |.||.:|||.|.....::|||:|||:.:....|:.:..|.||:..|.:..:.:...|||:...|.
plant   607 KLQLQQLMETLNSTEPHYIRCVKPNNLLQPTVFDNANVLHQLRSGGVLEAIRVKCAGYPTNRTFI 671

  Fly   708 DLYSMYKSVLPPELV--SLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFD----RIMR 766
            :..:.: .:|.||::  ...|...|:.:.:...|:.  ::.|.:|||.|.|:..|.|    |::
plant   672 EFLNRF-LILAPEILKGEYEAEVACKWILEKKGLTG--YQIGKSKVFLRAGQMAELDAHRTRVL- 732

  Fly   767 SDPENMLAIVAKVKKWLIRSRWVKSALGALCVIKLRNRIIYRNKCVLIAQRIARGFLARK--QHR 829
              .|:...|..:|:..|.|.|:|                :.|...|.| |...||.:|||  :..
plant   733 --GESARMIQGQVRTRLTRERFV----------------LMRRASVNI-QANWRGNIARKISKEM 778

  Fly   830 PRYQGIGKINK-IRTNTLK---------TIEIASGLK--MGREE-----------IISGVNDIYR 871
            .|.:...||.| :|....|         .:.:.||::  ..|.|           :|......|.
plant   779 RREEAAIKIQKNLRRQIAKKDYGKTKSSALTLQSGVRTMAARHEFRYKLTTRAATVIQAYWRGYS 843

  Fly   872 QIDDAIKKIK---------MNPRITQREMDSMYTVVMANMNKLTVDLNTKLKEQQQAEEQERLRK 927
            .|.| .||:|         :..||.::::.                   :.|:..:.||.|:.||
plant   844 AISD-YKKLKRVSLLCKSNLRGRIARKQLG-------------------QSKQADRKEETEKERK 888

  Fly   928 IQEALEAERAAK-----EAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEED-------RRA 980
            ::.:..||.|..     .:|:....|....::.|..:|:.....::..|..|:.|       |:.
plant   889 VELSNRAEEAVDMSFVLHSEQSDDAESGHGRKAKLSIESEDGLDKSSVLHSEQSDDEELGHERKT 953

  Fly   981 ALALQ-EQLEKEAKDDAKYRQQLEQERR-----------------------DHELALRLANESNG 1021
            .|::: |....:..||    :::|.||:                       |.|:..:...:.:.
plant   954 KLSIESEDGHSDQSDD----EEIEHERKTKHCIQAEDGIEKSYVMHSDQSDDEEIGHKRKTKHSI 1014

  Fly  1022 QVEDSPP---VIRNGVNDASPMGPNK---------------LISFSQ-------VVSNIASRYLN 1061
            |.||...   |:.:..:|...:|..:               .::.|:       |||.|.|...:
plant  1015 QAEDGIEKSFVVHSDQSDDEEIGHERKTKHAIQVEDGIQKSFVTCSEKPYNTFSVVSQITSPIRD 1079

  Fly  1062 -KSENVRAQQQAL------GKQKYDLSKWKYSELRDAINTSCDIELLEACR---QEFHRRLKVYH 1116
             :.|::.|:.:.|      .||:.|:|:.|.:|.|         ||.|..|   :|..||  ||.
plant  1080 TEIESLTAEVEMLKALLQVEKQRADISERKCAEAR---------ELGERRRKRLEETERR--VYQ 1133

  Fly  1117 AWKAKNRKRTTMDENERAPRSVMEA 1141
            ...:.||...:|.:.....:|::.:
plant  1134 LQDSLNRLLYSMSDQFSQLKSILRS 1158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..45	CDD:280832	15/45 (33%)
		Myosin_head	59..754	CDD:278492	268/702 (38%)
		MYSc_Myo6	71..754	CDD:276833	264/689 (38%)
		RILP-like	<968..1015	CDD:304877	13/77 (17%)
		Myosin-VI_CBD	1160..1246	CDD:293129
XIJ	NP_001319790.1	Myosin_N	9..46	CDD:397036	10/34 (29%)
		MYSc_Myo11	74..717	CDD:276835	264/689 (38%)
		IQ	829..849	CDD:197470	4/20 (20%)
		DUF460	<1081..>1142	CDD:421465	21/71 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59165
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920