Protein Alignment jar and myo1ha

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_009299653.1
• Gene: myo1ha / 556606
• ZFINID: ZDB-GENE-060531-78
• Length: 1059
• Species: Danio rerio
• Alignment Length: 1081
• Identity: 328/1081 - (30%)
• Similarity: 523/1081 - (48%)
• Gaps: 159/1081 - (14%)

  Fly    69 NEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIADK 133
            :|..||||||.|:.:|.||||:..:||:||||:|: ::|....:..|.|.:..|||||::|:||.
Zfish    59 SETAFLDNLKKRFTEDLIYTYIGTLLISVNPYKEL-DIYTKKQMDLYMGVNFFELPPHIYALADN 122

  Fly   134 AIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGPIET---KILDANPVLEAFGNA 195
            |...|.....:..|::||||||||||::|.:|:|...|..|:..::|   ::|.:||||||||||
Zfish   123 AYHTMLSEANNHFILISGESGAGKTEASKKILQYYAVSCPSSTLLDTVRDRMLMSNPVLEAFGNA 187

  Fly   196 KTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLR 260
            ||.:|:|||||||::::.:|.:...|||:|..|||||||:..|:..|||:|:||.|:.|..:.|.
Zfish   188 KTMKNDNSSRFGKYMDIQFDIQGDAVGGHILSYLLEKSRVVHQNHGERNFHIFYQLVEGGEEDLL 252

  Fly   261 DKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNLDKALGR 325
            .:|.|.: |..||   |          .|:.|...:.:.          |:|...:..:..||..
Zfish   253 RQLGLER-DTKRY---C----------YLVQGECSNVSS----------INDKNDWKTVKNALSV 293

  Fly   326 LGL--SDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVDQTELRT 388
            :..  ||||.|  :.::::||||||:.|:.   |.:|...::  |..:|...|.||||....|..
Zfish   294 IDFDASDTEHL--FGIISSVLHLGNVHFDR---DTKGYAILN--SNAALRWVSKLLGVHVQVLHG 351

  Fly   389 ALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPFQAS--NFY 451
            ||..|.:::     |...::.|..:..|..||||||||||.|.|..:|..||:|:..:.|  ...
Zfish   352 ALTFRKIEA-----KSEEVLSPYTVDHAIYARDALAKAIYDRAFTWLVNRINESLENKDSERKTV 411

  Fly   452 IGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQDIIE 516
            ||:|||.|||.||.||||||||||||||||:.|....||.|||.|:.||:....:.|.:|:.|.:
Zfish   412 IGLLDIYGFEVFTANSFEQFCINYCNEKLQQLFIQLTLKAEQEEYEAEGIGWEPVQFFNNKIICD 476

  Fly   517 LIEAKSNGIFTLLDEESKLPKPSYS-HFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDEEG-FLV 579
            |:|.|..||.::||||...|..:.. .|..::.:...||......:.:..|..::|  |.| |.:
Zfish   477 LVEEKHRGIISVLDEECVRPGDATDLTFLEKLEEKMGNHPHFVTHKLADKKTRKSL--ERGDFRL 539

  Fly   580 RHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPSGSSTSVRGKLNFISVGSKFKT 644
            .|:||.|.|....||:||||.|:.:::.:::...||::|..||   :|....:....:|.::||.
Zfish   540 LHYAGEVTYCVVGFIDKNNDLLYKNIKDMMRLSKNPIIQQCFP---ATKAESRRRPETVATQFKN 601

  Fly   645 QLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADL 709
            .|..|.|.|......::||:|.|......:|:..|...|:|..|.:..|.:...|:..|..:...
Zfish   602 SLLRLTEILTAKEAWYVRCLKSNDNKQQGKFDEVLVRHQVKYLGLMEHLRVRRAGFAYRRKYEVF 666

  Fly   710 YSMYKSVLP---PELVSLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGK--FVEFDRIMRSDP 769
            ...||.:.|   |....:|:.. .|.:.|.|.....::|.|.||:|.|..:  |...|.......
Zfish   667 LKRYKPLCPATWPHWRGVPSEG-VEKLVQHLGYQPDEYKMGRTKIFIRYARTLFATEDAFEICKH 730

  Fly   770 ENMLAIVAKVKKWLIRSRWVKSALGALCV------IKLRNRIIYRNKCVLIAQRIARGFLARKQH 828
            |....:.||.|.:.::..:.|....|..:      ::.|.....|...|.:.::..:|:|.|::.
Zfish   731 ELATKLQAKYKGYKVKGEFRKQKEAATKIETCWRGVQARKERDRRAWAVKVIKKFIKGYLTRREA 795

  Fly   829 ------------RPRYQGIGKINKIRTNTLKTIEIASGLKMGREEIISGVNDIYRQIDDAIKKIK 881
                        |..|     :|:::.|..||: :.....:....:::..::|.|::...:...|
Zfish   796 KTTDNSEYLAFVRQSY-----LNRLKANLPKTV-LDKTTWLTPPPVMTETSEILRKLHTRMMVRK 854

  Fly   882 MNPRIT-QREMDSMYTVVMANMNKLTVD----------LNTKLKEQQ------QAEEQERLRKIQ 929
            ....|| |::......||.:.:.|...|          ::|::.||.      |....||::...
Zfish   855 YVRGITPQKKAQMQQKVVTSAIFKGKKDSYPSSIAVPFVDTRINEQDINMRVLQTIRHERIKYSV 919

  Fly   930 EALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEEDRRAALALQEQLEKEAKD 994
            ..::.:|   ...:.|||:.|                    |.|      ||..|.|
Zfish   920 PVVKYDR---NGFKPRQRQLI--------------------LTQ------AAAHLVE-------- 947

  Fly   995 DAKYRQQLEQERRDHELALRLANESNGQVEDSPPVIRNGVNDASPMGP-----NKLISFSQVVSN 1054
            :||.:|:::.      ::|:.|:.||  :.||..::....||....|.     :.|......::.
Zfish   948 EAKIKQRVDY------VSLKGASVSN--LGDSVMILHVAFNDPKQKGDLVLQCDHLFEALTKLAM 1004

  Fly  1055 IASRYLNKSENVRAQQQALGKQKYDLSKWKYSELRDAINTS 1095
            ||    ||..|:...|   |..|:::...|    ::|::.|
Zfish  1005 IA----NKQNNITVVQ---GSIKFEIQAGK----QNAVDFS 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670
		MYSc_Myo6	71..754	CDD:276833	255/694 (37%)
		CBD_MYO6-like	765..913	CDD:409646	29/176 (16%)
		ERM_helical	<954..1020	CDD:466641	11/65 (17%)
		MYO6_MIU_linker	1002..1093	CDD:480843	20/95 (21%)
		MyUb_Myo6	1076..1116	CDD:439319	4/20 (20%)
		Myosin-VI_CBD	1160..1246	CDD:465157
myo1ha	XP_009299653.1	MYSc_Myo1	62..713	CDD:276829	255/693 (37%)
		Myosin_TH1	870..1051	CDD:461801	45/221 (20%)