Protein Alignment jar and myo1e.2

DIOPT Version :9

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_001011082.1
• Gene: myo1e.2 / 496494
• XenbaseID: XB-GENE-5913944
• Length: 1093
• Species: Xenopus tropicalis
• Alignment Length: 1182
• Identity: 342/1182 - (28%)
• Similarity: 533/1182 - (45%)
• Gaps: 253/1182 - (21%)

  Fly    60 DDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPD-TIKKYNGRSLGEL 123
            ||...|..:.|...::|||.||..|.|:||:..:||:|||::::.  |..| .|:.|.|.:..|.
 Frog    20 DDMVLLSKITEEAIMENLKKRYMDDYIFTYIGPVLISVNPFKQLP--YFTDREIEMYQGAAQYEN 82

  Fly   124 PPHVFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGP----IETKILD 184
            |||::|:||...|:|.:...:|.:|:|||||||||.:.||::.|:. .....||    ::..||.
 Frog    83 PPHIYALADTMYRNMLIDGENQCVIISGESGAGKTVAAKYIMGYVS-KVSGGGPKVQHVKDIILK 146

  Fly   185 ANPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFY 249
            :||:|||||||||.||||||||||:.|:.:....:..||.||::||||||:.:|::.||::|:||
 Frog   147 SNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVSQNSGERSFHIFY 211

  Fly   250 MLLAGAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQ 314
            .||.||..:.::.|.:..||.|.||:....|..:.                         :.|.:
 Frog   212 QLLEGASAEDKENLGVTSPDYYFYLNQSAVYHVDD-------------------------VSDKK 251

  Fly   315 HFHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLL 379
            .|.....|:..:||....:..:..:||.:|||||:||.|     .|...|.| |:..|...:.||
 Frog   252 EFAETMLAMDVVGLGPDTQTSVLQIVAGILHLGNVAFTE-----SGNHAVVE-SQDFLAFPAYLL 310

  Fly   380 GVDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIP 444
            |:||..|:..|.||.|.||.|| |..||.|.|...:|...|||||||:|:||||.:|..||:::.
 Frog   311 GIDQARLQDKLTSRKMDSKWGG-KSEVIDVTLNAEQACFTRDALAKALYTRLFDFLVEAINKAMR 374

  Fly   445 FQASNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFT 509
            .....:.||||||.|||.|..|.|||||||:.|||||:.|.:..||.|||.|.:||::...|.:.
 Frog   375 KDTEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIHWNPIEYF 439

  Fly   510 DNQDIIELIEAKSN--GIFTLLD-------------EESKLPK-----PSYSHFTAEVHKSWANH 554
            :|:.:.:|||:|.:  |:.::||             :::.|.|     .|:.||     .||
 Frog   440 NNKVVCDLIESKVSPPGVMSILDDVCATMHAKGEGADQTLLQKLQSAIGSHEHF-----NSW--- 496

  Fly   555 YRLGLPRSSRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQT 619
                               ..||::.|:||.|.|:...|.|:|.|.|...|..|:|..:.|.::.
 Frog   497 -------------------NRGFIIHHYAGKVSYDVSGFCERNRDVLFVDLIELMQSSEIPFIRE 542

  Fly   620 LFPSGSSTSVRGKLNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQL 684
            .||...:...:|:.:  :.|||.|.|..:|::.|.:...::|||||||.....|.:|.|....|:
 Frog   543 RFPENLNAEKKGRPS--TAGSKIKKQANDLVQTLMKCTPHYIRCIKPNETKKPRDWEDSRVKHQV 605

  Fly   685 KCSGTISVLELMEHGYPSRVLFADLYSMYKSVLPPELVSLPARTFCEA-----MFQSLNLSAKDF 744
            :..|....:.:...||..|.:|......| ::|..|  :.|.....|.     :.:|:|:.:..:
 Frog   606 EYLGLRENIRVRRAGYAYRRVFQKFLHRY-AILTRE--TWPQWRGDEKKGVMHLLRSVNMDSDQY 667

  Fly   745 KFGITKVFFR-PGKFVEFDRIMRSDPENMLAIVAK-------VKKWLIRSRWVKSALGALCVIKL 801
            :.|.||||.: |......:.:.....:|...::.|       |:|: ||.|...|:: .|...:.
 Frog   668 QLGRTKVFIKAPESLFLLEEMRERKYDNYARVIQKAWRKHTAVRKY-IRMREEASSI-VLNQKER 730

  Fly   802 RNRIIYRNKCVLIAQRIA-------RGFLARKQHRPRYQGIGKINKIRTNTLKTIEIASG---LK 856
            |...|.||   .:...|.       |.|:.|::.......:.|.:: |..|||...:.:.   ..
 Frog   731 RRNSINRN---FVGDYIGMDGRPELRQFVGRRERIDFADVVTKYDR-RFKTLKRDLVLTPKFLYL 791

  Fly   857 MGREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLNTKLKEQQQAEE 921
            :|||::..|.:.  .||.:.:|:        :.|::::.:|   :::||..|.
 Frog   792 IGREKVKQGPDK--GQIKEVLKR--------KIELENIQSV---SLSKLQDDF------------ 831

  Fly   922 QERLRKIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEEDRRA-----A 981
                     .:..|.|...|.|...:.|..:...|               |.||:..|.     .
 Frog   832 ---------IILHEGAYDSALEGVFKTEFLSLLYK---------------RYEEKTHRKLPIKFG 872

  Fly   982 LALQEQLEKE--AKDDAKYRQQLEQERRDHELALRLANESNGQV------EDSPPVIRNGVNDAS 1038
            |.|:.:::||  |...|...:|::.:....::||   .::||:|      ...||..|....|
 Frog   873 LQLEFKVKKEGWAPWGAAGTRQIQFQTGIGDMAL---TKANGKVLIVTIGPGLPPNSRPTRKD-- 932

  Fly  1039 PMGPNKLISFSQVVSNIASRYLNKSENVRAQQQALGKQKYDLSKWKYSELRDAINTSCDIELLEA 1103
                           |..|:|:..:.  ...|:|.|..|                .|....:|:
 Frog   933 ---------------NRKSQYMGSAP--AGNQRANGGNK----------------KSSRPPMLQ- 963

  Fly  1104 CRQEFHRRLKVYHAWKAKNRKRTTMDENERAPRSVMEAAFKQPPLVQPIQEIVTAQHRYFRIPFM 1168
             |..|..|..|         ::.|:.....:||:      |.||             ....:.||
 Frog   964 -RMSFTSRQSV---------EQPTLPRQGASPRA------KAPP-------------TQANLDFM 999

  Fly  1169 RANAPDNTKRGL 1180
              |.||....|:
 Frog  1000 --NVPDQGAAGI 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..45	CDD:280832
		Myosin_head	59..754	CDD:278492	256/723 (35%)
		MYSc_Myo6	71..754	CDD:276833	252/712 (35%)
		RILP-like	<968..1015	CDD:304877	13/53 (25%)
		Myosin-VI_CBD	1160..1246	CDD:293129	6/21 (29%)
myo1e.2	NP_001011082.1	MYSc_Myo1	31..677	CDD:276829	252/712 (35%)
		Myosin_TH1	717..918	CDD:368706	50/257 (19%)
		SH3_MyoIe_If_like	1040..1092	CDD:212761

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122881at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010