Protein Alignment jar and Myo61F

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Alignment Length: 890
• Identity: 288/890 - (32%)
• Similarity: 453/890 - (50%)
• Gaps: 100/890 - (11%)

  Fly    69 NEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIADK 133
            :|..|:.|||.|:.:|.||||:..:||:||||::: .:|..|.:|.|..:...|:|||:||:.|.
  Fly    50 SEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQL-PIYTDDHVKAYRNKHFYEMPPHIFAVTDN 113

  Fly   134 AIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGPIE---TKILDANPVLEAFGNA 195
            |.|.:......|.:::|||||:||||::|.:|:::.....:...:|   .|:|.:||||||||||
  Fly   114 AFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNA 178

  Fly   196 KTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLR 260
            ||.||:|||||||::::.:|.|...:||.|.:|||||||:..|...|||:|:||.|||||.:.|.
  Fly   179 KTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALL 243

  Fly   261 DKLSLGKP-DDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNLDKALG 324
            .:|.|.:. |.|.||   |.......|.                      |:|...|..:.:||.
  Fly   244 QELRLERALDTYSYL---TDGLNGTVTR----------------------INDADSFKQVQQALT 283

  Fly   325 RLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSG-LLGVDQTELRT 388
            .:..:..|:..|:.:||::|||||:.|.|    |.|..:|   :.:.|.:|:. ||||:.:||..
  Fly   284 VIDFTKEEQREIFGIVASILHLGNVGFTE----VEGNAKV---NSRDLVVTAARLLGVNASELEA 341

  Fly   389 ALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPFQ----ASN 449
            ||..|.:.:     :|.|:..||....|..||||||||:|.|||..:|..:|.|:..:    :.|
  Fly   342 ALTHRTIDA-----RGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRN 401

  Fly   450 FYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQDI 514
            ..:|:|||.|||.|..|||||||||:||||||:.|.:..||:||:.|:|||:....:.:.||:.|
  Fly   402 NVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVI 466

  Fly   515 IELIEAKSNGIFTLLDEESKLP-KPSYSHFTAEVHKSWANHYRLGLPRSSRLKAH---RTLRDEE 575
            ..|||.|..||.::||||...| :|:...|..::.:..|.|:....  ..:..||   ..||||
  Fly   467 CNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVC--HEKAPAHIKKIMLRDE- 528

  Fly   576 GFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPSGSSTSVRGKLNFISVGS 640
             |.:.|:||.|.|:...|::||||.|...|:..:.:..|.:::..||.....|::.....|   :
  Fly   529 -FRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAI---T 589

  Fly   641 KFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSR-- 703
            :|:..|..||:.|.....::|||||||.......|...|.|.|:|..|.:..|.:...|:..|
  Fly   590 QFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRT 654

  Fly   704 -VLFADLY-SMYKSVLPPELVSLPARTFCEAMFQSLNLSAKDFKFGITKVFFR-PGKFVEFDRIM 765
             .||.:.| |:.||..|........:...:.:.:.|....:.::.|.||:|.| |....:.:...
  Fly   655 YELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAY 719

  Fly   766 RSDPENMLAIVAKVKKWLIRSRWVKSALGALCVIKLRNRIIYRNKCVLIAQRIARGFLARKQHRP 830
            :.....:.||        |::.| |..:.....:|||.::|       |.|...|..||::..:.
  Fly   720 QEKKHEIAAI--------IQAHW-KGLMQRRKYLKLRAQVI-------IMQSYCRRKLAQQAAKK 768

  Fly   831 RYQGIGKINKIRTNTLKTIEIASGLKMGREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMY 895
            |.:...||.......:...:..:|.   .||.|:....::        .:::...:..:.:|..:
  Fly   769 RREAADKIRAFIKGFITRNDAPNGF---NEEFIANAKRMW--------LLRLAKELPTKVLDKSW 822

  Fly   896 ----------TVVMANMNKLTVDLNTKLKEQQQAEEQERLRKIQE 930
                      :.::..:::|.:....:||...|.:.|..|:.:.|
  Fly   823 PHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAE 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670
		MYSc_Myo6	71..754	CDD:276833	256/699 (37%)
		CBD_MYO6-like	765..913	CDD:409646	23/157 (15%)
		ERM_helical	<954..1020	CDD:466641
		MYO6_MIU_linker	1002..1093	CDD:480843
		MyUb_Myo6	1076..1116	CDD:439319
		Myosin-VI_CBD	1160..1246	CDD:465157
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	256/699 (37%)
		Myosin_TH1	863..1049	CDD:461801	1/5 (20%)