Protein Alignment jar and zip

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0287873
• Length: 2056
• Species: Drosophila melanogaster
• Alignment Length: 1387
• Identity: 388/1387 - (27%)
• Similarity: 609/1387 - (43%)
• Gaps: 331/1387 - (23%)

  Fly     6 QLVWVRDAAEGYIQGRITEIGAKEFEVTPTDRKYPKRTCHF-DDIHSSCDGPQDHD---DNCELM 66
            :||||....:|::...|......|.||...:.  .||.... |||...  .|...|   |..||.
  Fly    80 RLVWVPHENQGFVAASIKREHGDEVEVELAET--GKRVMILRDDIQKM--NPPKFDKVEDMAELT 140

  Fly    67 LLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIA 131
            .||||:.|.|:|.|||...||||.....:.||||::: .:|....:::|.|....|:|||||||.
  Fly   141 CLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKL-PIYTEKIMERYKGIKRHEVPPHVFAIT 204

  Fly   132 DKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCY-------------------------- 170
            |.|.|:|...:..|||:.:|||||||||:||.::::|.|
  Fly   205 DSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTN 269

  Fly   171 ----------------------------SHDSAGPIETKILDANPVLEAFGNAKTTRNNNSSRFG 207
                                        |:...|.:|.::|.|||:|||||||||.:|:||||||
  Fly   270 KYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFG 334

  Fly   208 KFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLRDKLSLGKPDDYR 272
            |||.:::||...:.|..|..|||||||...|:.:||.:|:||.|||||..:.|:|..|.....|.
  Fly   335 KFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDDVKSYA 399

  Fly   273 YLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNLDKALGRLGLSDTEKLGIY 337
            :||                          .|.|..|.:|||..|....|::..:|::..:...|:
  Fly   400 FLS--------------------------NGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIF 438

  Fly   338 SLVAAVLHLGNIAFEE--------IPDDVRGGCQVSEASEQSLTITSGLLGVDQTEL-RTALVSR 393
            .:|:|||..|::.|.:        :||:.     |::.       .:.|||:..|:: |..|..|
  Fly   439 RIVSAVLLFGSMKFRQERNNDQATLPDNT-----VAQK-------IAHLLGLSVTDMTRAFLTPR 491

  Fly   394 VMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSI---PFQASNFYIGVL 455
            :   |.|  :..|.....| .:...|.:|:|||.|.|:|..:|..||:|:   ..|.::| ||:|
  Fly   492 I---KVG--RDFVTKAQTK-EQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASF-IGIL 549

  Fly   456 DIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITF-TDNQDIIELIE 519
            |:||||.|.:|||||.||||.|||||:.||..:...|||.|:|||:....|.| .|.|..|:||:
  Fly   550 DMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLID 614

  Fly   520 AKSNGIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDEEGFLVRHFAG 584
             |..||..|||||...||.:...|..::..:.:.|     |:..:    ...|....|.:.|:||
  Fly   615 -KPGGIMALLDEECWFPKATDKTFVDKLVSAHSMH-----PKFMK----TDFRGVADFAIVHYAG 669

  Fly   585 AVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPS----------------GSSTSVRGKL 633
            .|.|:..:::.||.|.|:.::..|:|...:|.:..::..                |:.|.   |.
  Fly   670 RVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVGMAQQALTDTQFGARTR---KG 731

  Fly   634 NFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEH 698
            .|.:|...:|.||.:||:.|.....||:|||.||.:....:.:..|.|.||:|:|.:..:.:...
  Fly   732 MFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQ 796

  Fly   699 GYPSRVLFADLYSMYKSVLPPELVS---LPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVE 760
            |:|:|:.|.:....|: :|.|.::.   :..:..||.|.|:|.|.:..::.|.:|:|||.|
  Fly   797 GFPNRIPFQEFRQRYE-LLTPNVIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAG---- 856

  Fly   761 FDRIMRSDPENMLAIVAKVKKWLIRSRWVKSALGALCVIKLRNRIIYRNKCVLIAQRIARGFLAR 825
                       :||.:.:.:.:.|                        :..::..|...||||||
  Fly   857 -----------VLAHLEEERDFKI------------------------SDLIVNFQAFCRGFLAR 886

  Fly   826 KQHRPRYQGIGKINKIRTNTLKTIEIASGLKMGREEIISGVNDIYRQIDDAIKKIKMNPRITQRE 890
            :.::.|.|.:..|..|:.|      .|:.||:...:...    :|.::...::..|...::.|:|
  Fly   887 RNYQKRLQQLNAIRIIQRN------CAAYLKLRNWQWWR----LYTKVKPLLEVTKQEEKLVQKE 941

  Fly   891 MDSMYTVVMANMNKLTVDLNTKLKEQQQAEEQERLRKIQEAL------------EAERAAKEAEE 943
            .:         :.::...|:|..|..|:.|     ||.|:||            |.|..| ||||
  Fly   942 DE---------LKQVREKLDTLAKNTQEYE-----RKYQQALVEKTTLAEQLQAEIELCA-EAEE 991

  Fly   944 QRQR-----EEIENKRLKAEMETRRKAAEAQRLRQEEEDRRAALA------------LQEQLEKE 991
            .|.|     :|:|:  :..|:|||         .:|||:|..||.            |:||||:|
  Fly   992 SRSRLMARKQELED--MMQELETR---------IEEEEERVLALGGEKKKLELNIQDLEEQLEEE 1045

  Fly   992 AKDDAKYRQQLEQERRD-----HELALRLANESNGQVEDSPPVIRNGVNDASPMGPNKLISFSQV 1051
              :.|:.:.|||:.:.|     :|..|.|.::.|.::.....::....||.|    ..|....:.
  Fly  1046 --EAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLS----QTLAEEEEK 1104

  Fly  1052 VSNIASRYLNKSENVRAQQQALGK-----QKYDLSKWK----YSELRDAINTSCDIELLEACRQE 1107
            ..::|.........:...::.|.|     |:.|.||.|    .::|::.:|
  Fly  1105 AKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLN-------------- 1155

  Fly  1108 FHRRLKV--YHAWKAKNRKRTT-----MDENERAPRSVMEAAFKQPPLVQPIQEIVTAQHRYFRI 1165
             .||::|  ..|..||..:..|     :||......:..:|..:....:..|||.:.|:..
  Fly  1156 -ERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKA---- 1215

  Fly  1166 PFMRANAPDNTKRGLWYAHFDGQWIARQMELHADKPPILLVAGT------------DDMQMCELS 1218
              .||.| :..:|.|            ..||.|.|..:|....|            .::...:.|
  Fly  1216 --ARAKA-EKVRRDL------------SEELEALKNELLDSLDTTAAQQELRSKREQELATLKKS 1265

  Fly  1219 LEETGLTRKRGAEILEHEFNRE 1240
            |||..:..:.....:.|:.::|
  Fly  1266 LEEETVNHEGVLADMRHKHSQE 1287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670	12/42 (29%)
		MYSc_Myo6	71..754	CDD:276833	250/768 (33%)
		CBD_MYO6-like	765..913	CDD:409646	24/147 (16%)
		ERM_helical	<954..1020	CDD:466641	24/82 (29%)
		MYO6_MIU_linker	1002..1093	CDD:480843	20/104 (19%)
		MyUb_Myo6	1076..1116	CDD:439319	10/45 (22%)
		Myosin-VI_CBD	1160..1246	CDD:465157	17/93 (18%)
zip	NP_523860.2	Myosin_N	79..122	CDD:460670	12/43 (28%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	250/768 (33%)
		Myosin_tail_1	931..2011	CDD:460256	94/423 (22%)