Protein Alignment jar and LOC1278822

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_061507801.1
• Gene: LOC1278822 / 1278822
• VectorBaseID: AGAMI1_005641
• Length: 3010
• Species: Anopheles gambiae
• Alignment Length: 1440
• Identity: 347/1440 - (24%)
• Similarity: 522/1440 - (36%)
• Gaps: 514/1440 - (35%)

  Fly    57 QDHDDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLG 121
            :::.|.|:|..|||||.|:||:.|:....|||||.:|||||||:: ...:|.|..::.|..:.:|
Mosquito   166 REYPDLCQLPDLNEATLLENLRQRFEAGHIYTYVGSILIAVNPFK-FHPIYNPKYVRLYQNQRIG 229

  Fly   122 E-LPPHVFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCY-----SHDSAGPIET 180
            . ||||:|||||.|..:|...|.:|.|::|||||:||||||.:||.:|..     :|.|.  :|.
Mosquito   230 PILPPHIFAIADNAYYNMLKEKRNQCIVISGESGSGKTESTNFLLHHLTALSQKGAHGSG--VEQ 292

  Fly   181 KILDANPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNY 245
            .||.|.|||||||||||..|||||||||||:|:|.....|.|..:..||||||||.:|...||||
Mosquito   293 TILSAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYRENGMVQGAVVQKYLLEKSRIVSQGHYERNY 357

  Fly   246 HVFYMLLAGAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPII 310
            ||||.||:||....||.|.|...:.|.||        |||...|       :|           .
Mosquito   358 HVFYYLLSGATDAERDALHLLPAEKYHYL--------NAKNLTL-------EN-----------C 396

  Fly   311 DDYQHFHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTIT 375
            |:...|..|.:::..:|.|..::..::::::|||.|||:.|............|...:...:.:.
Mosquito   397 DEKYEFSRLKQSMEMVGFSAEKQRRLFNVLSAVLLLGNVEFFPKKSTYHHDESVQVRNPDVVGLI 461

  Fly   376 SGLLGVDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLIN 440
            |.||.|.|..|.:||.|:.:::.|    .|:|| ..|:.||..|||||||.:|..|||.||..:|
Mosquito   462 SELLRVKQETLMSALTSKRVKASG----ETLIM-QYKLPEAIAARDALAKCLYGALFDWIVLQVN 521

  Fly   441 QSI----PFQASNFYIGVLDIAGFEYF-TVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREG 500
            .::    ....:...||||||.|||.| ..|||||.||||.||.||.:||.::.|.||:.|||||
Mosquito   522 HALLNKDQVLHTGHSIGVLDIFGFEDFGPQNSFEQLCINYANEHLQYYFNLHVFKYEQKEYKREG 586

  Fly   501 LNVPEITFTDNQDIIELIEAKSNGIFTLLDEESKLPKPSYSHFTAE---VHKSWANHYRLGLPRS 562
            :...:|.|.||...::|.|:|.:|:..:||:....|..:......:   |||..|.:
Mosquito   587 IKWTDIEFLDNYGCLQLFESKPSGLLCILDDLCNFPGATNETLLQKFNSVHKDNAFY-------- 643

  Fly   563 SRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECD----------NP-- 615
                 .:..|.|..|:::|:||.|.|...:..|||.|.:...:..:::...          :|
Mosquito   644 -----EKPQRKENAFIIKHYAGKVKYQVAEMREKNLDLMRQDIVSVLKNSSMAFVRELVGADPVA 703

  Fly   616 -----LLQTLF---------------------------------PSGSSTS-------------- 628
                 :|:..|                                 |:.|..|
Mosquito   704 VFRWAILRAFFRGYFAFRSAGIKHRKERADMSYNKLATKTRYRAPNDSIVSHLVTVSSVNLTINR 768

  Fly   629 ----------VR----------------------------------------------------- 630
                      ||
Mosquito   769 IAKLFCARRPVRDAGMLDRYRNYSTKSATAKGGQRERRKNWPKRISNAMSDITSGHSNNQACSPN 833

  Fly   631 ----------------------------------------------GKLNF-------------- 635
                                                          ||||:
Mosquito   834 SNLAYHRQSLGNAGYGAAGAASPGATGGTPRRSWSSFAFNNKNFPDGKLNYECNQQQDQTPQYHS 898

  Fly   636 ----------------------------------------------------------------- 635
                                                                             
Mosquito   899 KHLQSTAASSSSIYGSGGGGKSSANANSSASGAPNSGGVTGTGSGKGYGLGSAAARNRFERSGQD 963

  Fly   636 -----------------------------------------------------ISVGSKFKTQLG 647
                                                                 ::|.::|:..|.
Mosquito   964 VMARASQIVMKNKSFRPRERPKKGLKNLQSVKTLSAGQNLSNQTSAIKTRKQPLTVTAQFQNSLI 1028

  Fly   648 ELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSM 712
            .|||.|.|....||||||.|...|..||:.:....||:.:|.:..:.:...||..|:.:.:...:
Mosquito  1029 ALMETLNQANPFFIRCIKSNPNKIPNQFDDATVTRQLRYTGMLETVRIRRAGYNVRLTYEEFIQL 1093

  Fly   713 YKSVLPPELVS--LPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLAI 775
            |:.:||..|||  ...|.|...|    :|:.:.::.|:||::.|..:.:..|          :::
Mosquito  1094 YRILLPKGLVSSQKDVRDFMSTM----DLNKQHYQLGLTKIYMRESQKMRLD----------ISL 1144

  Fly   776 VAKVKKWLI-RSRWVKSAL---------GALCVI-------------KLRNRIIYRNKCVLIAQR 817
            ..|:...:| ..||.::.|         .|.|.|             |...:|  ||....:.|.
Mosquito  1145 HTKIIDSIICIQRWFRAILQRKKYCQYRNAACTIQSYWRDYLREKQEKFTRKI--RNHAATVIQA 1207

  Fly   818 IARGFLARK-------------------QHRPRYQGI--GKINKIRTNTLKTIEI---------- 851
            ..||:..||                   |.|.|::.:  .|:.:.|.....|..:
Mosquito  1208 TWRGYTVRKWYSKLKTGVLIIQARIRGNQARSRFKELLSKKLQRERAKLRSTQSLPVERPIGTTA 1272

  Fly   852 ASGLKMGREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANM-----NKLTVDLNT 911
            |.|...|......|....|.:|..||:..|.......|..::...:|..|.     :.::.|...
Mosquito  1273 AGGSYGGGGGGAGGGGSTYPEIVHAIEHRKKPIPAVGRSFETAIDIVNKNRALFADDSMSADFID 1337

  Fly   912 KLKEQQQAEEQERLRKIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEEE 976
            ..:::::.||:|.....|..:.|....:|.:|:...|..|:..|..:             .|...
Mosquito  1338 DDEDEEEEEEEETTGSRQATITATCGEEEEDEEDDEEGYEDLGLVDD-------------PQYMA 1389

  Fly   977 DRRAAL------------------ALQEQLEKEAKDDAKYRQQLEQERRDHELALRLANESNGQV 1023
            :.|:||                  ||.::.||..|                .|.:..........
Mosquito  1390 NNRSALMHPVKTAAPVTTSPTVNSALLDRNEKYIK----------------SLVISGGGGGGATA 1438

  Fly  1024 EDSPPVIRNGVNDASPMGPNKLISFSQVVSNIASRY----LNKSENVRAQQ------QALGKQKY 1078
            ..||.....|..:||.:|           |:::..|    |.:.|:|..:.      :...|..:
Mosquito  1439 SSSPSAGGGGGGNASSVG-----------SSVSGAYQKAPLQRQEDVLDRPLRMYDIERASKSTF 1492

  Fly  1079 D---LSKWKY 1085
            |   |:|::|
Mosquito  1493 DDTELAKYRY 1502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670
		MYSc_Myo6	71..754	CDD:276833	267/1003 (27%)
		CBD_MYO6-like	765..913	CDD:409646	36/206 (17%)
		ERM_helical	<954..1020	CDD:466641	11/83 (13%)
		MYO6_MIU_linker	1002..1093	CDD:480843	17/97 (18%)
		MyUb_Myo6	1076..1116	CDD:439319	4/13 (31%)
		Myosin-VI_CBD	1160..1246	CDD:465157
LOC1278822	XP_061507801.1	None