Protein Alignment jar and jar

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_061517154.1
• Gene: jar / 1272367
• VectorBaseID: AGAMI1_003334
• Length: 1259
• Species: Anopheles gambiae
• Alignment Length: 1273
• Identity: 906/1273 - (71%)
• Similarity: 1046/1273 - (82%)
• Gaps: 36/1273 - (2%)

  Fly     4 DTQLVWVRDAAEGYIQGRITEIGAKEFEVTPTDRKYPKRTCHFDDIHSSCDGPQDHDDNCELMLL 68
            |:||||.||..:||||||||||||.|::|.|.|.|.|||:|..:||..||:.|.|:|||||||.|
Mosquito     3 DSQLVWARDIQDGYIQGRITEIGASEYDVQPVDSKLPKRSCIPEDIFPSCERPSDNDDNCELMFL 67

  Fly    69 NEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELPPHVFAIADK 133
            ||||.|||::.|||||||||||||||||||||:||.:||:..|:|:|:|:|:|||||||:|||||
Mosquito    68 NEATLLDNIRNRYYKDKIYTYVANILIAVNPYKEIPDLYSTATLKRYSGKSIGELPPHVYAIADK 132

  Fly   134 AIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGPIETKILDANPVLEAFGNAKTT 198
            |||||||.|:|||||||||||||||||||||||:||.|..:|||||.|||||||:||||||||||
Mosquito   133 AIRDMRVLKMSQSIIVSGESGAGKTESTKYLLKFLCDSVAAAGPIEQKILDANPILEAFGNAKTT 197

  Fly   199 RNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYMLLAGAPQQLRDKL 263
            |||||||||||||||||.:||||||:|||||||||||||||.:||||||||:|.||||..||::|
Mosquito   198 RNNNSSRFGKFIEVHYDKRCQVVGGHISHYLLEKSRICTQSPDERNYHVFYLLCAGAPPALRERL 262

  Fly   264 SLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQHFHNLDKALGRLGL 328
            :|.||||||||.||||||.:..||..||...||:.|..||||||||:|||:.|..||:|||||||
Mosquito   263 ALTKPDDYRYLCGCTQYFTHPHTESRIPAGHKSRVHAAKGPLKDPILDDYEDFRQLDEALGRLGL 327

  Fly   329 SDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLGVDQTELRTALVSR 393
            |:.|:..||||||||||||||.|||.|:|..|||::::.|:.||.:|:.|:|||.:|||.||:||
Mosquito   328 SEAERTQIYSLVAAVLHLGNIRFEENPEDSNGGCRITQESQPSLNVTARLIGVDPSELRQALMSR 392

  Fly   394 VMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPFQASNFYIGVLDIA 458
            ||:|||||.|||||||.||:|||:|||||||||:||:|||.||.||||:||||||::||||||||
Mosquito   393 VMKSKGGGIKGTVIMVMLKVYEANNARDALAKALYSKLFDHIVSLINQNIPFQASSYYIGVLDIA 457

  Fly   459 GFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTDNQDIIELIEAKSN 523
            ||||||||||||||||||||||||||:||||..||.||.|||||||||.:|||||||||||:|||
Mosquito   458 GFEYFTVNSFEQFCINYCNEKLQKFFDDNILAAEQVLYAREGLNVPEIKYTDNQDIIELIESKSN 522

  Fly   524 GIFTLLDEESKLPKPSYSHFTAEVHKSWANHYRLGLPRSSRLKAHRTLRDEEGFLVRHFAGAVCY 588
            |||||||||||||:|||:|||.|||.:|..||||..||:|||||||:|||:||||||||||||||
Mosquito   523 GIFTLLDEESKLPRPSYAHFTNEVHSAWNGHYRLSFPRASRLKAHRSLRDDEGFLVRHFAGAVCY 587

  Fly   589 NTEQFIEKNNDALHASLEGLVQECDNPLLQTLFP---SGSSTSVRGKLNFISVGSKFKTQLGELM 650
            ||.||||||||||||||||||||.:|.||..||.   :|.|....|||:||||||||::|||||:
Mosquito   588 NTNQFIEKNNDALHASLEGLVQESENALLNALFSGGGAGKSPMNVGKLSFISVGSKFRSQLGELL 652

  Fly   651 EKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSMYKS 715
            |||..|||||||||||||:|||.:|||||||||||.|||.|||||||:||||||.|.:||:||||
Mosquito   653 EKLRNNGTNFIRCIKPNSRMIDHEFEGSLALAQLKYSGTNSVLELMEYGYPSRVPFNELYNMYKS 717

  Fly   716 VLPPELVSLPARTFCEAMFQSLNLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLAIVAKVK 780
            .|||||..|..|||||||..||.|::.:||||||||||||||||||||||||||||:.|||||||
Mosquito   718 YLPPELARLAPRTFCEAMLMSLKLNSNEFKFGITKVFFRPGKFVEFDRIMRSDPENLQAIVAKVK 782

  Fly   781 KWLIRSRWVKSALGALCVIKLRNRIIYRNKCVLIAQRIARGFLARKQHRPRYQGIGKINKIRTNT 845
            ||||||||:|||..|:|||||:||||:|||.|::.|:..||:|.||:|:|||:||.||..:..|.
Mosquito   783 KWLIRSRWIKSAFAAICVIKLKNRIIFRNKSVVLLQKTIRGYLVRKKHQPRYRGIAKIKAVEDNL 847

  Fly   846 LKTIEIASGLKMGREEIISGVNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLN 910
            .|...||..||..|:::.:.:.|:...:..|:.||:.||.|....:|..|..:|.:::.....:|
Mosquito   848 RKMHAIAEQLKADRDKMQANIRDVQASLTAAVAKIRANPSIGAAAIDQQYADIMRSIDTNMKLIN 912

  Fly   911 TKLKEQQQAEEQERLRKIQEALEAERAAKEAEEQRQREEIENKRLKAEMETRRKAAEAQRLRQEE 975
            .:|:||:.|||||||.||:.||||||.|||.||:|.|||.||::.|.|:|.|||..||:|||||.
Mosquito   913 ARLQEQRNAEEQERLNKIKLALEAERRAKEEEERRLREEEENRKRKTEIEARRKEEEAKRLRQEG 977

  Fly   976 EDRRAALALQEQLEKEAKDDAKYRQQLEQERRDHELALRLANESNGQVEDSPPVIRNGVNDASPM 1040
            |||:||||||.||||||::|.:|||||||||||||||||||.|||||||||||.:|||..:.:|:
Mosquito   978 EDRKAALALQAQLEKEAQEDIQYRQQLEQERRDHELALRLAQESNGQVEDSPPALRNGTPEVTPL 1042

  Fly  1041 G-PNKLISFSQVVSNIASRYLNKSENVRAQQQALGKQKYDLSKWKYSELRDAINTSCDIELLEAC 1104
            | .|:||               :||.:|||||.:.|||:||||||||||||||||||||||||||
Mosquito  1043 GNANRLI---------------RSEAIRAQQQLVEKQKHDLSKWKYSELRDAINTSCDIELLEAC 1092

  Fly  1105 RQEFHRRLKVYHAWKAKNRKRTTMDENERAPRSVMEAAFKQPPLVQPIQEIVT--AQHRYFRIPF 1167
            |.||||||||||||||||||||||||||||||||||||.:.||.:.|.||||.  :.||||||||
Mosquito  1093 RHEFHRRLKVYHAWKAKNRKRTTMDENERAPRSVMEAAARSPPRLTPKQEIVPTGSVHRYFRIPF 1157

  Fly  1168 MR--------------ANAPDNTKRGLWYAHFDGQWIARQMELHADKPPILLVAGTDDMQMCELS 1218
            :|              ||| |::||..|:||||||::|||||||.||||||||||.|||||||||
Mosquito  1158 VRPSNGGGPAEIGTAAANA-DDSKRSWWFAHFDGQYVARQMELHTDKPPILLVAGKDDMQMCELS 1221

  Fly  1219 LEETGLTRKRGAEILEHEFNREWERNGGKAYKNLGAAK 1256
            ||||.|||||||||||||||||||::|||.|..|.|.|
Mosquito  1222 LEETALTRKRGAEILEHEFNREWEQHGGKPYNRLSARK 1259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670	26/41 (63%)
		MYSc_Myo6	71..754	CDD:276833	525/685 (77%)
		CBD_MYO6-like	765..913	CDD:409646	71/147 (48%)
		ERM_helical	<954..1020	CDD:466641	49/65 (75%)
		MYO6_MIU_linker	1002..1093	CDD:480843	57/91 (63%)
		MyUb_Myo6	1076..1116	CDD:439319	37/39 (95%)
		Myosin-VI_CBD	1160..1246	CDD:465157	71/99 (72%)
jar	XP_061517154.1	None