Protein Alignment jar and LOC100495968

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_002935256.2
• Gene: LOC100495968 / 100495968
• XenbaseID: XB-GENE-29082907
• Length: 1941
• Species: Xenopus tropicalis
• Alignment Length: 1343
• Identity: 375/1343 - (27%)
• Similarity: 606/1343 - (45%)
• Gaps: 280/1343 - (20%)

  Fly     2 LEDTQLVWVRDAAEGYIQGR-------ITEIGAKEFEVTPTDRK-YPKRTCHFDDIHSSCDGPQD 58
            ::||..::|:    |:|..|       .||.|..|   |.|:.: |.:....:|.|
 Frog    40 IDDTNTLFVK----GFITARDGDKITVKTEDGRTE---TVTESQIYQQNPPKYDKI--------- 88

  Fly    59 HDDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGEL 123
             :|...:..|||.:.|.|||.||....||||.....|.||||:.: .:|.|:.:..|.|:...|.
 Frog    89 -EDMAMMTHLNEPSVLFNLKERYAAWMIYTYSGLFCITVNPYKWL-PVYNPEVVAGYRGKKRVEA 151

  Fly   124 PPHVFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLC-------------YSHDSA 175
            |||:|:|:|.|.:.|...:.:||::::||||||||.:||.:::|..             ..::..
 Frog   152 PPHIFSISDNAYQSMLTDRENQSVLITGESGAGKTVNTKRVIQYFATVAAIGDAGKKKQADNNLK 216

  Fly   176 GPIETKILDANPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSA 240
            |.:|.:|:.|||:|||||||||.||:|||||||||.:|:....::....|..|||||||:..|.:
 Frog   217 GTLEDQIIQANPLLEAFGNAKTLRNDNSSRFGKFIRIHFGTTGKLSSADIETYLLEKSRVTFQLS 281

  Fly   241 EERNYHVFYMLLAGAPQQLRDKLSL-GKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGP 304
            .||:||:||.:|.....:|.:.|.| ..|.||..:|                          :|.
 Frog   282 AERSYHIFYQILTNKIPELIEMLLLTTNPYDYPTIS--------------------------QGE 320

  Fly   305 LKDPIIDDYQHFHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASE 369
            ||...|||...|...:.|:..||.:..|::.||.:..||:|.||:.|::...:.:.....:|.::
 Frog   321 LKVKSIDDEDEFMATESAIEVLGFNAEERVSIYKMTGAVMHHGNMKFKQKQREEQAEPDGTEVAD 385

  Fly   370 QSLTITSGLLGVDQTELRTAL-VSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFD 433
            :    .|.|:|::..:|..|| ..||  ..|..|......||    :..|:..||.|::|.:||.
 Frog   386 K----ISYLMGLNSADLLKALCYPRV--KVGNEFVTKSQTVP----QVCNSVGALCKSVYEKLFL 440

  Fly   434 RIVGLINQSIPF-QASNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYK 497
            .:|..|||.:.. |...|:||||||||||.|..||.||.|||:.|||||:|||.::...|||.||
 Frog   441 WMVTRINQQLDTKQPRQFFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVQEQEEYK 505

  Fly   498 REGLNVPEITF-TDNQDIIELIEAKSNGIFTLLDEESKLPK---PSYSHFTAEVHKSWANHYRLG 558
            :||:....|.| .|....||||| |..|||::|:||...||   .|:.:...|.|.....::...
 Frog   506 KEGIEWEFIDFGMDLAACIELIE-KPMGIFSILEEECMFPKATETSFKNKLYEQHLGKCKNFEKP 569

  Fly   559 LPRSSRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLF-- 621
            .|...:.:||        |.:.|:||.|.||...:::||.|.|:.|:..|.|:....||..|:
 Frog   570 KPGKGKAEAH--------FSLVHYAGIVDYNISGWLDKNKDPLNDSVVQLYQKSSVKLLSFLYSS 626

  Fly   622 ----PSGSSTSVRG------KLNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFE 676
                .|||.:|.:|      ..:|.:|.:.|:..|.:||..|.....:|:||:.||........:
 Frog   627 YASADSGSDSSSKGGGKKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGIMD 691

  Fly   677 GSLALAQLKCSGTISVLELMEHGYPSRVLFADLYSMYK----SVLPPELVSLPARTFCEAMFQSL 737
            ..|.:.||:|:|.:..:.:...|:|||:.:.|....||    |.: |:...:.::...|.:..|:
 Frog   692 NYLIIHQLRCNGVLEGIRICTKGFPSRIQYGDFKQRYKILNASAI-PDGQFIDSKKAAEKLLGSI 755

  Fly   738 NLSAKDFKFGITKVFFRPGKFVEFDRIMRSDPENMLA-IVAKVKKWLIRSRWVKSALGALCVIKL 801
            ::....::||.|||||:.|.....:. ||   :.||| ::.:::.:         ..|.|..|:.
 Frog   756 DVDHNQYRFGHTKVFFKAGLLGTLEE-MR---DEMLAHVITRIQSY---------CRGYLMRIEF 807

  Fly   802 RNRIIYRNKCVLIAQRIARGFLARKQHRPRYQGIGKINKIRTNTLKTIEIASGLKMGREEIISGV 866
            : ::..|.:.:.:.|...|.|:..| |.|..:...||..:    ||:.|        .|:.::.:
 Frog   808 K-KMNSRREALFVIQYNLRSFMNVK-HWPWMKLYFKIKPL----LKSAE--------TEKEMANI 858

  Fly   867 NDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKL------------------------TV 907
            .:.|.:|.:|::|.:..    ::|::....|::...|.|                        .:
 Frog   859 KEEYEKIKEALEKAEAR----KKELEEKMVVLLQEKNDLMLQAQAESETLADAEERCESLIKGKI 919

  Fly   908 DLNTKLK---------EQQQAEEQERLRKIQEAL--------EAERAAKEAEEQRQREEIENKRL 955
            .|.:|:|         |:..||...:.||:::..        |.|....:.|:::...|.:.|.|
 Frog   920 QLESKIKEMTERLEDEEESNAELSAKKRKLEDECSELKKDIDELEITLSKVEKEKHATENKVKNL 984

  Fly   956 KAEME---------TRRK----AAEAQRL--RQEEEDR-----RAALALQEQ---LEKEAKDDAK 997
            ..:|.         |:.|    .|..|.|  .|.|||:     :|...|::|   ||...:.:.|
 Frog   985 TEDMAALDDNISKVTKEKKSLQEAHQQTLDDLQTEEDKVNTLSKAKSKLEQQVDDLEGSLEQEKK 1049

  Fly   998 YRQQLEQERRDHELALRLANESNGQVEDSPPVIRNGVNDASPMGPNKLISFSQVVSNIASRYLNK 1062
            .|..||:.:|..|..|:|..|:                         ::.|
 Frog  1050 LRLDLERTKRKLECDLKLTQET-------------------------VLDF-------------- 1075

  Fly  1063 SENVRAQ-QQALGKQKYDLSKWKYSELRDAINTSCDIELLEACRQEFHRRLKVYHAWKAKNRKRT 1126
             ||.:.| ::.|.|:.|::|: ..|::.|.          :|...:..:::|...|      :..
 Frog  1076 -ENDKQQAEERLKKKDYEISQ-LLSKIEDE----------QALSSQLQKKIKELQA------RTE 1122

  Fly  1127 TMDENERAPRSVMEAAFKQPPLV--------QPIQEIVTAQHRYFRIPFMRANAPDNTKRGLWYA 1183
            .::|...|.|:|...|.||..|:        :.::|...|......:...|.|.....:|.|..|
 Frog  1123 ELEEEIEAERTVRAKAEKQRALITRELEEISERLEEAGGATAVQIEMNKKRENEFQKMRRDLEEA 1187

  Fly  1184 HFDGQWIARQM-ELHADKPPILLVA----GTDDMQMCELSLEE 1221
            :...:.||..: :.|||     .||    ..|::|..:..||:
 Frog  1188 NLRHETIACNLRKKHAD-----TVAELGEQLDNLQRIKQKLEK 1225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670	12/49 (24%)
		MYSc_Myo6	71..754	CDD:276833	248/718 (35%)
		CBD_MYO6-like	765..913	CDD:409646	30/172 (17%)
		ERM_helical	<954..1020	CDD:466641	25/88 (28%)
		MYO6_MIU_linker	1002..1093	CDD:480843	17/91 (19%)
		MyUb_Myo6	1076..1116	CDD:439319	6/39 (15%)
		Myosin-VI_CBD	1160..1246	CDD:465157	16/67 (24%)
LOC100495968	XP_002935256.2	Myosin_N	33..77	CDD:460670	12/43 (28%)
		MYSc_class_II	100..772	CDD:276951	248/718 (35%)
		Myosin_tail_1	852..1929	CDD:460256	86/440 (20%)