Protein Alignment jar and myo1e

DIOPT Version :10

• Sequence 1: NP_001014650.2
• Gene: jar / 42889
• FlyBaseID: FBgn0011225
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_001121497.2
• Gene: myo1e / 100158599
• XenbaseID: XB-GENE-1005591
• Length: 1108
• Species: Xenopus tropicalis
• Alignment Length: 966
• Identity: 303/966 - (31%)
• Similarity: 467/966 - (48%)
• Gaps: 170/966 - (17%)

  Fly    60 DDNCELMLLNEATFLDNLKTRYYKDKIYTYVANILIAVNPYREIKELYAPDTIKKYNGRSLGELP 124
            ||...|..:.|.:.:||||.||..|.|:||:..:||:|||:::: ..:....|:.|.|.:..|.|
 Frog    22 DDMVLLSKITEDSIVDNLKKRYMDDFIFTYIGPVLISVNPFKQM-PYFGDKEIEMYQGAAQYENP 85

  Fly   125 PHVFAIADKAIRDMRVYKLSQSIIVSGESGAGKTESTKYLLKYLCYSHDSAGP----IETKILDA 185
            ||::|:||...|:|.:.:.:|.:|:|||||||||.:.||::.|:. .....||    ::..||.:
 Frog    86 PHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYIS-KVSGGGPKVQHVKDIILQS 149

  Fly   186 NPVLEAFGNAKTTRNNNSSRFGKFIEVHYDAKCQVVGGYISHYLLEKSRICTQSAEERNYHVFYM 250
            ||:|||||||||.||||||||||:.|:.:....:..||.||::||||||:..::..||::|:||.
 Frog   150 NPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQ 214

  Fly   251 LLAGAPQQLRDKLSLGKPDDYRYLSGCTQYFANAKTEQLIPGSQKSKNHQQKGPLKDPIIDDYQH 315
            |:.||.:..|:.|.:...|.|.||:                         |.|..|...|:|.:.
 Frog   215 LIEGASKDQRESLGITSLDYYNYLN-------------------------QSGSYKVDDINDKRD 254

  Fly   316 FHNLDKALGRLGLSDTEKLGIYSLVAAVLHLGNIAFEEIPDDVRGGCQVSEASEQSLTITSGLLG 380
            |.....|:..:|:|...:..:..:||.|||||||.|:|     :|.....| :|:.|...:.|||
 Frog   255 FQETMHAMNVIGISAEGQAMVMQIVAGVLHLGNIGFKE-----KGNYAAVE-NEEFLAFPAFLLG 313

  Fly   381 VDQTELRTALVSRVMQSKGGGFKGTVIMVPLKIYEASNARDALAKAIYSRLFDRIVGLINQSIPF 445
            ::|:.|:..|.||.|.||.|| |...|.|.|.:.:|...||||:||::||:||.:|..||:::..
 Frog   314 INQSRLKDKLTSRQMDSKWGG-KSESINVTLNVEQACYTRDALSKALHSRVFDYLVDSINKAMKK 377

  Fly   446 QASNFYIGVLDIAGFEYFTVNSFEQFCINYCNEKLQKFFNDNILKNEQELYKREGLNVPEITFTD 510
            ....:.||||||.|||.|..|.|||||||:.|||||:.|.:..||.|||.|.:||:....|.:.:
 Frog   378 DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFN 442

  Fly   511 NQDIIELIEAKSN--GIFTLLD-------------EESKLPKPSYSHFTAEVHKSWANHYRLGLP 560
            |:.:.:|||.|.|  |:.::||             :::.|.|...:..|.|...||
 Frog   443 NKIVCDLIENKVNPPGVMSILDDVCATMHAVGEGADQTLLQKLQMAVGTHEHFNSW--------- 498

  Fly   561 RSSRLKAHRTLRDEEGFLVRHFAGAVCYNTEQFIEKNNDALHASLEGLVQECDNPLLQTLFPSGS 625
                         .:||::.|:||.|.|:.:.|.|:|.|.|...|..|:|....|.:|.|||...
 Frog   499 -------------NQGFIIHHYAGKVSYDVDGFCERNRDVLFMDLIELMQSSQQPFMQALFPENL 550

  Fly   626 STSVRGKLNFISVGSKFKTQLGELMEKLEQNGTNFIRCIKPNSKMIDRQFEGSLALAQLKCSGTI 690
            ....:|:..  :.|||.|.|..:|:..|.:...::|||||||.....|.:|.|....|::..|..
 Frog   551 QAEKKGRPT--TAGSKIKKQANDLVNTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLK 613

  Fly   691 SVLELMEHGYPSRVLFADLYSMYKSVLPPELVSLPARTFCEA-----MFQSLNLSAKDFKFGITK 750
            ..:.:...||..|.:|......| ::|..|  :.|:....|.     :..|:|:.:..|:.|.||
 Frog   614 ENIRVRRAGYAYRRVFKKFLQRY-AILTKE--TWPSWKGDEKKGVLHLLHSVNMDSDQFQLGKTK 675

  Fly   751 VFFRPGKFV---------EFDRIMRSDPENMLAIVAKVKKWLIRSRWVKSALGALCVIKLRNRI- 805
            :|.:..:.:         ::|...||       |....:|::.|.::|          ::|.:.
 Frog   676 IFIKAPESLFLLEEMRERKYDGYARS-------IQKAWRKYVARKKYV----------QMREQAS 723

  Fly   806 -IYRNKCVLIAQRIARGFLA---RKQHRPRY-QGIGKINKI--RTNTLKTIEIASGLK------- 856
             ::.||.......|.|.|:.   ....||.. |.:||..||  .....|....:.|:|
 Frog   724 DLFLNKKERRRNSINRNFIGDYIGMDERPELRQFVGKREKIDFADTVTKYDRRSKGVKRDLILTP 788

  Fly   857 -----MGREEIISG-----VNDIYRQIDDAIKKIKMNPRITQREMDSMYTVVMANMNKLTVDLNT 911
                 :||:::..|     |.::.:      |||.:. ||                  |:|.|:|
 Frog   789 KSVYLIGRDKMKQGPEKGLVKEVLK------KKIDVE-RI------------------LSVSLST 828

  Fly   912 KLKEQQQAEEQERLRKIQEALEAE---RAAKEAEEQRQRE------EIENKRLKAE 958
            ...:.....|||....::...:.|   ..:|..||:.||:      .|.:.:||.|
 Frog   829 MQDDFFILHEQEYDSLLESLFKTEFISLLSKHYEEKTQRKLPLKFNNILDMKLKKE 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jar	NP_001014650.2	Myosin_N	7..49	CDD:460670
		MYSc_Myo6	71..754	CDD:276833	250/706 (35%)
		CBD_MYO6-like	765..913	CDD:409646	35/172 (20%)
		ERM_helical	<954..1020	CDD:466641	3/5 (60%)
		MYO6_MIU_linker	1002..1093	CDD:480843
		MyUb_Myo6	1076..1116	CDD:439319
		Myosin-VI_CBD	1160..1246	CDD:465157
myo1e	NP_001121497.2	MYSc_Myo1	33..679	CDD:276829	250/706 (35%)
		Myosin_TH1	719..921	CDD:461801	42/191 (22%)
		SH3_MyoIe_If_like	1055..1107	CDD:212761