DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beta-PheRS and AT1G72550

DIOPT Version :9

Sequence 1:	NP_651237.1	Gene:	beta-PheRS / 42888	FlyBaseID:	FBgn0039175	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_177399.1	Gene:	AT1G72550 / 843587	AraportID:	AT1G72550	Length:	598	Species:	Arabidopsis thaliana

Alignment Length:	600	Identity:	304/600 - (50%)
Similarity:	419/600 - (69%)	Gaps:	19/600 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPTIGVKRDLLFEALGKTYTDDEFQDLCFAFGLELDEVTTEKQMLTKEQGDVAAAANASEEIIYR 65
            ||||.|.||.||.|||::||.::|::|||:||:|||:|||||.::.||: .:...|:..|||||:
plant     1 MPTISVGRDRLFAALGESYTQEKFEELCFSFGIELDDVTTEKAIIRKEK-HIDEEADDDEEIIYK 64

  Fly    66 IDIPANRYDLLCLEGLVTGLLVFQGKLKPPKFQFVELAKRQVLK--IDPSTAQIRPYAVAAVLRN 128
            |:|||||.||||||||...|.||..|.:.|.:...:::|.::|:  :.|.|::|||:.|.||||.
plant    65 IEIPANRPDLLCLEGLAQSLRVFIEKQEIPTYTLADISKDKILQMNVKPETSKIRPFVVCAVLRG 129

  Fly   129 VTFTQASYNSFIDLQDKLHQNICRKRTLVAIGTHDLDTLQGPFSYEALAPDQIKFKPLNQTKEMT 193
            |||.:|.|||||||||||||||||:|:||||||||||||||||:||||.|..|.|.||.|||...
plant   130 VTFDEARYNSFIDLQDKLHQNICRRRSLVAIGTHDLDTLQGPFTYEALPPTDINFVPLKQTKSFR 194

  Fly   194 GSELMDFYSTHAQLKQYLPIIRESPVYPVIYDANRVVLSLPPIINGDHSKITLKTKNVFIECTAT 258
            ..||::||.:..:||::|.||..|||:||:||:.|.||||||||||.||.|||:|||||||||||
plant   195 ADELIEFYKSDMKLKKFLHIIENSPVFPVLYDSKRTVLSLPPIINGAHSAITLQTKNVFIECTAT 259

  Fly   259 DRTKAKVVLDTIVCLFSEHCAQKFTVEPCDVVQPDGSVISYPELEVREERISVKRANAYIGIDEP 323
            |.||||:||:|:|..|||.||:||.:||.:|...||....||:|.|.:..:.:......||:...
plant   260 DLTKAKIVLNTMVTTFSEFCARKFEIEPVEVTYDDGKSYIYPDLAVYDMEVPLSFITDSIGVSLK 324

  Fly   324 AEKLADMLTRMYLEAKVDGDS-----LVVKIPPTRHDVIHACDIYEDVAIAYGYNNIKKSLPAFM 383
            .|::..:||||.|:|:....|     :.|.:||:|.||:|.||:.||||||||:|||....||.:
plant   325 VEQVTSLLTRMQLQAEQAKSSDNQCAIKVHVPPSRSDVLHPCDVMEDVAIAYGFNNIPTRKPASI 389

  Fly   384 QIAKQFPLNKLTEQLREQVAQAGFTEALTFTLCSRDDIGRKLNKNIDALPAVHIGNPKTLEFQVV 448
               |...||:||:.||.::|...:||.:|:.|||..:....||:. |...||.:|||::.:|:.:
plant   390 ---KPLTLNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNRE-DVNSAVIVGNPRSADFEAM 450

  Fly   449 RTTLLPGLLKTLVANRKMPLPLKLFEISDVVVADESTEVGARNERRVCAVNCNKTAGFEVVHGLL 513
            |..|:||||||:..|.|.|.|:|:|||||||:.|||.:|||.|.|.:.|:.|..|:|||::|||:
plant   451 RRALMPGLLKTVGHNNKYPKPIKIFEISDVVMLDESKDVGASNRRHLAALYCGATSGFELIHGLV 515

  Fly   514 DRVMQLLSVPWKS-------ASGTKGYYLQATEDPSYFPGRCANVMYDGVVIGKIGVLHPTVLQA 571
            ||:|:::::|:.:       .:...|||::.:::|.:.|||.|:::..|..||..|::||.||..
plant   516 DRIMEVMAIPFLTIHENNVPINEKDGYYVKLSQEPEFLPGRQASIIVRGKHIGNFGIVHPEVLNN 580

  Fly   572 FELTTPCSAVEFTIE 586
            |::..|||.:|..||
plant   581 FDIPDPCSYLELDIE 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta-PheRS	NP_651237.1	PLN02265	1..589	CDD:215149	303/599 (51%)
		B3_4	118..279	CDD:214876	112/160 (70%)
		B5	310..372	CDD:281482	26/66 (39%)
		PheRS_beta_core	390..588	CDD:238392	85/203 (42%)
AT1G72550	NP_177399.1	PLN02265	1..598	CDD:215149	303/599 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	234	1.000	Domainoid score	I633
eggNOG	1	0.900	-	-		E1_COG0072
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4160
Inparanoid	1	1.050	598	1.000	Inparanoid score	I224
OMA	1	1.010	-	-		QHG62210
OrthoDB	1	1.010	-	-		D378921at2759
OrthoFinder	1	1.000	-	-		FOG0004315
OrthoInspector	1	1.000	-	-		oto3865
orthoMCL	1	0.900	-	-		OOG6_101233
Panther	1	1.100	-	-	LDO	PTHR10947
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3585
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840