DRSC/TRiP Functional Genomics Resources

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Protein Alignment beta-PheRS and LRRC47

DIOPT Version :9

Sequence 1:NP_651237.1 Gene:beta-PheRS / 42888 FlyBaseID:FBgn0039175 Length:589 Species:Drosophila melanogaster
Sequence 2:NP_065761.1 Gene:LRRC47 / 57470 HGNCID:29207 Length:583 Species:Homo sapiens


Alignment Length:267 Identity:76/267 - (28%)
Similarity:130/267 - (48%) Gaps:29/267 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   108 LKIDPSTAQIRPYAVAAVLRNVTFTQA-SYNSFIDLQDKLHQNICRKRTLVAIGTHDLDTLQGPF 171
            :::.|....:|||.|.||:|.:..... :...|:..|.|||:::|.|||...:.||:|..::||.
Human   323 VRVSPEVRDVRPYIVGAVVRGMDLQPGNALKRFLTSQTKLHEDLCEKRTAATLATHELRAVKGPL 387

  Fly   172 SYEALAPDQIKFKPLNQTKEMTGSELMDFYSTHAQ-------------LKQYLPIIRESPVYPVI 223
            .|.|..|..:|..||.: ||....||:......|:             |.:||.::..:..||.:
Human   388 LYCARPPQDLKIVPLGR-KEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGNENYPCL 451

  Fly   224 YDANRVVLSLPPIINGDHSKITLKTKNVFIECT-ATDRTKAKVVLDTIVCLFSEHCAQKFTVEPC 287
            .||:..|:|.|||.|.:.:|:...|.::|:|.| ||.....|.|:|.::...:|  .:|:|:|. 
Human   452 VDADGDVISFPPITNSEKTKVKKTTSDLFLEVTSATSLQICKDVMDALILKMAE--MKKYTLEN- 513

  Fly   288 DVVQPDGSVISYPELEVREERISVKRANAYIGIDEPAEKLADMLTRMYLEAKVDGDSLVVKIPPT 352
               :.:|| :|..|.:....::.....|...|.|.|:..:.:.:..:.||.     ||.| :.|:
Human   514 ---KEEGS-LSDTEADAVSGQLPDPTTNPSAGKDGPSLLVVEQVRVVDLEG-----SLKV-VYPS 568

  Fly   353 RHDVIHA 359
            :.|:..|
Human   569 KADLATA 575

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
beta-PheRSNP_651237.1 PLN02265 1..589 CDD:215149 76/267 (28%)
B3_4 118..279 CDD:214876 56/175 (32%)
B5 310..372 CDD:281482 12/50 (24%)
PheRS_beta_core 390..588 CDD:238392
LRRC47NP_065761.1 LRR 44..>239 CDD:227223
leucine-rich repeat 52..76 CDD:275380
LRR 1 76..95
leucine-rich repeat 77..100 CDD:275380
LRR 2 100..121
leucine-rich repeat 101..130 CDD:275380
LRR 3 130..152
leucine-rich repeat 131..154 CDD:275380
LRR 4 154..175
leucine-rich repeat 155..180 CDD:275380
LRR 5 180..202
leucine-rich repeat 181..203 CDD:275380
LRR 6 203..225
leucine-rich repeat 204..226 CDD:275380
LRR 7 226..246
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 260..300
pheT 317..>507 CDD:236592 57/186 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 513..544 6/35 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D431403at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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