Protein Alignment beta-PheRS and frs1

DIOPT Version :10

• Sequence 1: NP_651237.1
• Gene: beta-PheRS / 42888
• FlyBaseID: FBgn0039175
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_594442.1
• Gene: frs1 / 2541974
• PomBaseID: SPAC23A1.12C
• Length: 589
• Species: Schizosaccharomyces pombe
• Alignment Length: 603
• Identity: 278/603 - (46%)
• Similarity: 385/603 - (63%)
• Gaps: 28/603 - (4%)

  Fly     1 MPTIGVKRDLLFEALGKTYTDDEFQDLCFAFGLELDEVTTEKQMLTKEQGDVAAAANASEEIIYR 65
            ||||...::.|::|||:.||..||.:|||.||:||||.||..           ...:.||....:
pombe     1 MPTISCDKEELYKALGREYTTQEFDELCFQFGIELDEDTTND-----------PERSPSERPSLK 54

  Fly    66 IDIPANRYDLLCLEGLVTGLLVFQGKLKPPKFQFVELAKRQVLKIDPSTAQIRPYAVAAVLRNVT 130
            |||||||||:|||||:...|.||..::..|:::.  |.....|.|.|.|::|||||.||:||.|.
pombe    55 IDIPANRYDMLCLEGIAQALNVFNRRMATPQYKL--LPSTTSLTISPETSEIRPYAAAAILRGVK 117

  Fly   131 FTQASYNSFIDLQDKLHQNICRKRTLVAIGTHDLDTLQGPFSYEALAPDQIKFKPLNQTKEMTGS 195
            .....|.|||.||||||.|:||.||||||||||...::|||:||||.|::|.|.|||||:|:.||
pombe   118 LDPIRYQSFIALQDKLHANLCRNRTLVAIGTHDFSVMEGPFTYEALKPEEINFVPLNQTQEINGS 182

  Fly   196 ELMDFYSTHAQLKQYLPIIRESPVYPVIYDANRVVLSLPPIINGDHSKITLKTKNVFIECTATDR 260
            .|::||.....|.:||.||..||.||||.||.|.|.|||||||.:.|||::.|:::||:.||||:
pombe   183 NLLEFYKDSKHLSRYLHIIANSPRYPVILDAKRRVCSLPPIINSEFSKISVDTRDIFIDVTATDK 247

  Fly   261 TKAKVVLDTIVCLFSEHCAQKFTVEPCDVV-QPDGSVISYPELEVREERISVKRANAYIGIDEPA 324
            ||.::|::.:..:||.:|.:.||:||.::: :.:|.....|.|.....:..:...|...|:..|.
pombe   248 TKLEIVVNMMTTMFSCYCEEPFTIEPVNIISEHNGCTRVTPNLNPTCFKADIDYLNEACGLSLPE 312

  Fly   325 EKLADMLTRMYLEAKV---DGDSLVVKIPPTRHDVIHACDIYEDVAIAYGYNNIKKSLPAF-MQI 385
            :::..:||||.|.||.   |..:|:|.:||.|.|::|.|||.||:.|||||:|:|.:.||. :..
pombe   313 DEICHLLTRMMLTAKPNPNDSKTLLVYVPPLRADILHQCDIMEDLGIAYGYDNLKHTYPAHSVTF 377

  Fly   386 AKQFPLNKLTEQLREQVAQAGFTEALTFTLCSRDDIGRKLNKNIDALPAVHIGNPKTLEFQVVRT 450
            .|.|.:|:|.:.:|.:||.||::|.:.|.|||.|:....|.|..|: .||.:.|||||||||||:
pombe   378 GKPFEVNRLADIIRNEVAYAGWSEVMPFILCSHDENYAWLRKTDDS-KAVQLANPKTLEFQVVRS 441

  Fly   451 TLLPGLLKTLVANRKMPLPLKLFEISDVVVADESTEVGARNERRVCAVNCNKTAGFEVVHGLLDR 515
            :||||:|||:..|:...||:|:||:|||...|.|.|...||||.:||:.....:|||.:||||||
pombe   442 SLLPGILKTVRENKNHALPIKIFEVSDVAFCDYSRERMTRNERHLCAIFAGLNSGFEQIHGLLDR 506

  Fly   516 VMQLLS---VPWKSASGTKGYYLQATEDPSYFPGRCANVMY------DGVVIGKIGVLHPTVLQA 571
            ||.:|:   :.....|...||:::|.:|.::||||||.|.|      .|:.:|..|||||.||:.
pombe   507 VMLMLNTKRIMNPKDSDAVGYWIEAEDDSTFFPGRCAAVYYRKDFGTAGIRVGVFGVLHPLVLEK 571

  Fly   572 FELTTPCSAVEFTIEPFV 589
            ||||:..||||..:..:|
pombe   572 FELTSAASAVEIDLTLWV 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beta-PheRS	NP_651237.1	PLN02265	1..589	CDD:215149	277/601 (46%)
frs1	NP_594442.1	PLN02265	1..585	CDD:215149	277/597 (46%)