DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beta-PheRS and lrrc47

DIOPT Version :9

Sequence 1:	NP_651237.1	Gene:	beta-PheRS / 42888	FlyBaseID:	FBgn0039175	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_001120634.1	Gene:	lrrc47 / 100145802	XenbaseID:	XB-GENE-967812	Length:	570	Species:	Xenopus tropicalis

Alignment Length:	265	Identity:	81/265 - (30%)
Similarity:	127/265 - (47%)	Gaps:	31/265 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 VLKIDPSTAQIRPYAVAAVLRNVTFTQA-SYNSFIDLQDKLHQNICRKRTLVAIGTHDLDTLQGP 170
            |:.:.|||..:|||.|..|::.:..... :...|:..|.|||..:|.||||..|.||||..::||
Frog   311 VVNVSPSTKDVRPYIVCCVVKGMNLKPGNALKRFLTAQTKLHDEMCDKRTLATIATHDLRLVKGP 375

  Fly   171 FSYEALAPDQIKFKPLNQTKEMTGSELMDFYSTHAQ-------------LKQYLPIIRESPVYPV 222
            ..|:|..|..:|..||.: ||:...:|:......|:             |.:||.::.....||.
Frog   376 LLYDARPPKDLKVVPLGR-KEINAKDLVRQLQFEAEEQRKQKKRQNVSGLHKYLHLLDSKENYPC 439

  Fly   223 IYDANRVVLSLPPIINGDHSKITLKTKNVFIECTA-TDRTKAKVVLDTIVCLFSEHCAQKFTVEP 286
            :.|....|:|.|||.|.:.:||...|:|||:|.|: |.....|.||||::...:|  ..|||:|.
Frog   440 LIDTENAVISFPPITNSEKTKIWKSTQNVFVEVTSGTSLQVCKDVLDTLILKMAE--LHKFTLEN 502

  Fly   287 CDVVQPDGSVISYPELEVREERISVKRANAYIGIDEPAEKLADMLTRMYLEAKVDGDSLVVKIPP 351
               .:|:....|.||...::|..:....:|..|        |.::......|.:||:..|  :.|
Frog   503 ---KEPEAISDSEPEAVDKQEPAANNNPDAETG--------AQLIVEQVRVADMDGNLKV--LYP 554

  Fly   352 TRHDV 356
            ::.|:
Frog   555 SKTDL 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta-PheRS	NP_651237.1	PLN02265	1..589	CDD:215149	81/265 (31%)
		B3_4	118..279	CDD:214876	59/175 (34%)
		B5	310..372	CDD:281482	9/47 (19%)
		PheRS_beta_core	390..588	CDD:238392
lrrc47	NP_001120634.1	PLN03150	<9..119	CDD:178695
		leucine-rich repeat	51..74	CDD:275380
		LRR	<73..>227	CDD:227223
		leucine-rich repeat	75..97	CDD:275380
		leucine-rich repeat	98..120	CDD:275380
		leucine-rich repeat	121..143	CDD:275380
		leucine-rich repeat	144..168	CDD:275380
		leucine-rich repeat	169..191	CDD:275380
		leucine-rich repeat	192..214	CDD:275380
		PLN02265	313..>501	CDD:215149	65/190 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D431403at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920