DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spps and Klf13

DIOPT Version :9

Sequence 1:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_067341.2	Gene:	Klf13 / 50794	MGIID:	1354948	Length:	289	Species:	Mus musculus

Alignment Length:	315	Identity:	104/315 - (33%)
Similarity:	139/315 - (44%)	Gaps:	80/315 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   551 SIKQEPPDTFGPISATGNPPAP----ASTPNTASPQQQQIKFLHTESNSLSSLSIPASIQITALP 611
            ::..||.:        |..|.|    |:.|......:::      :....:||.:.|.| :..|.
Mouse    22 AVVHEPRE--------GPEPRPEGAAAAAPTLPRVDERR------DGKDSASLFVVARI-LADLN 71

  Fly   612 QQATNTPNTPATTQPIPVSLPARSKVNAVTTSS-TQITI-----APTGGQVVSVTTQARGATASI 670
            |||             |...||..:..|....: |...:     ||..|...:...|| ||.|:
Mouse    72 QQA-------------PAPAPAERREGAAARKARTPCRLPPAPPAPPPGPEPASPGQA-GAPAA- 121

  Fly   671 RSTNTSTTTITTPSQSHLNMNISVASVGGAATGGGGGTATGEP--KPRLKRVACTCPNCTDGEKH 733
                       .||.:......::....|.|       .:|||  :.|.:|          |...
Mouse   122 -----------PPSPAWSEPEAALEQEPGPA-------GSGEPGLRQRGRR----------GRSR 158

  Fly   734 SD---KKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRRTHT 795
            :|   .:|:|.||..||.|||||:|||:||||.|||||||.|||..|.|:|.|||||.||.||||
Mouse   159 ADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQECNKKFARSDELARHYRTHT 223

  Fly   796 GEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETKGGNAPKSIS 850
            |||:|.|..|.|:|||||||:||.:.|.....|       :.|...||:...|:|
Mouse   224 GEKKFSCPICEKRFMRSDHLTKHARRHANFHPG-------MLQRRGGGSRTGSLS 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	61/104 (59%)
		C2H2 Zn finger	742..764	CDD:275368	16/21 (76%)
		zf-H2C2_2	756..783	CDD:290200	19/26 (73%)
		C2H2 Zn finger	772..794	CDD:275368	14/21 (67%)
		zf-H2C2_2	786..809	CDD:290200	15/22 (68%)
		zf-C2H2	800..822	CDD:278523	13/21 (62%)
		C2H2 Zn finger	802..822	CDD:275368	12/19 (63%)
Klf13	NP_067341.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..54		7/44 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..168		29/140 (21%)
		COG5048	<163..253	CDD:227381	59/89 (66%)
		C2H2 Zn finger	170..192	CDD:275368	16/21 (76%)
		C2H2 Zn finger	200..222	CDD:275368	14/21 (67%)
		C2H2 Zn finger	230..250	CDD:275368	12/19 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	250..289		7/29 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910