DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spps and sp5a

DIOPT Version :9

Sequence 1:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_851304.2	Gene:	sp5a / 353154	ZFINID:	ZDB-GENE-030430-2	Length:	368	Species:	Danio rerio

Alignment Length:	270	Identity:	107/270 - (39%)
Similarity:	136/270 - (50%)	Gaps:	41/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   569 PPAPASTPNTASPQQQQIKFLHTESNSLSSLSIPASIQITALPQQATNTPNTPATTQPIPVSLPA 633
            |||..:.|...||    :|.|.....||.|...|..:...           |.|...|||.::|:
Zfish   111 PPADPTYPYDFSP----VKMLPCSMQSLQSTCPPTYVPAV-----------TYAAPAPIPPAMPS 160

  Fly   634 RSKVNAVTTSSTQITIAPTGGQVVSVTTQARGATASIRSTNTSTTTITTPSQSHL--------NM 690
            ....::......|..::|..|:.:...:..:|...:     .|......|.|..|        ..
Zfish   161 FVPGHSGLVHQQQRQLSPNPGEDIPWWSLQQGNPVA-----HSVHPHRFPIQRGLVLGHTDFAQY 220

  Fly   691 NISVASVGGAATGGGGGTATGEPKPRLKRV-ACTCPNCTDGEKHSD--KKRQHICHITGCHKVYG 752
            ...:|::          ..|..|....:|. .|.||||.......:  ||:||||||.||.||||
Zfish   221 QTQIAAL----------LHTKSPLATARRCRRCRCPNCQSSSSSDEPGKKKQHICHIPGCGKVYG 275

  Fly   753 KTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSK 817
            |||||:||||||:|||||||:|.||||.||||||||||.|||||||||.|.:|.|:|||||||:|
Zfish   276 KTSHLKAHLRWHSGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFVCPDCCKRFMRSDHLAK 340

  Fly   818 HIKTHFKSRS 827
            |:|||...:|
Zfish   341 HVKTHQNKKS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	74/103 (72%)
		C2H2 Zn finger	742..764	CDD:275368	18/21 (86%)
		zf-H2C2_2	756..783	CDD:290200	21/26 (81%)
		C2H2 Zn finger	772..794	CDD:275368	17/21 (81%)
		zf-H2C2_2	786..809	CDD:290200	17/22 (77%)
		zf-C2H2	800..822	CDD:278523	14/21 (67%)
		C2H2 Zn finger	802..822	CDD:275368	13/19 (68%)
sp5a	NP_851304.2	C2H2 Zn finger	268..287	CDD:275368	15/18 (83%)
		zf-H2C2_2	279..306	CDD:290200	21/26 (81%)
		C2H2 Zn finger	295..317	CDD:275368	17/21 (81%)
		zf-H2C2_2	309..332	CDD:290200	17/22 (77%)
		C2H2 Zn finger	325..345	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1085860at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6780
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	6.010