DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spps and Sp8

DIOPT Version :9

Sequence 1:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_001178703.1	Gene:	Sp8 / 299499	RGDID:	1307619	Length:	504	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	115/286 - (40%)
Similarity:	135/286 - (47%)	Gaps:	90/286 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   618 PNTPATTQPIPVSL-PARSKVNAVTTSSTQITIAPTGGQVVSVTTQARGATASIRSTNTSTTTIT 681
            ||..|.   :|.|| ||...:.....|       |.||    ..:...|.:.|..|:..| :.:.
  Rat   241 PNGAAA---LPGSLHPAAGGLQTSLHS-------PLGG----YNSDYSGLSHSAFSSGAS-SHLL 290

  Fly   682 TPSQSHL---------------------NMNISVASVGGAATGGGGGTATGEPKPRLK----RVA 721
            :|:..||                     ....|:.|.|.||..|      |.|:...:    |..
  Rat   291 SPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGSSMLSAGPAAPLG------GSPRSSARRYSGRAT 349

  Fly   722 CTCPNCTDGEKHSD------KKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKR 780
            |.||||.:.|:...      :|..|.|||.||.|||||||||:||||||||||||||:|.|||||
  Rat   350 CDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKR 414

  Fly   781 FTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETKGGNA 845
            ||||||||||.|||||||||.|..|||:||||||||||:|||    ||
  Rat   415 FTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTH----SG----------------- 458

  Fly   846 PKSISTVNGIVTIEIPGGGSAAAGSG 871
                            |||||.:|.|
  Rat   459 ----------------GGGSAGSGGG 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	76/107 (71%)
		C2H2 Zn finger	742..764	CDD:275368	18/21 (86%)
		zf-H2C2_2	756..783	CDD:290200	23/26 (88%)
		C2H2 Zn finger	772..794	CDD:275368	18/21 (86%)
		zf-H2C2_2	786..809	CDD:290200	18/22 (82%)
		zf-C2H2	800..822	CDD:278523	16/21 (76%)
		C2H2 Zn finger	802..822	CDD:275368	15/19 (79%)
Sp8	NP_001178703.1	C2H2 Zn finger	379..398	CDD:275368	15/18 (83%)
		zf-H2C2_2	390..417	CDD:290200	23/26 (88%)
		C2H2 Zn finger	406..428	CDD:275368	18/21 (86%)
		zf-H2C2_2	420..443	CDD:290200	18/22 (82%)
		zf-C2H2	434..456	CDD:278523	16/21 (76%)
		C2H2 Zn finger	436..456	CDD:275368	15/19 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010