DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spps and sptf-2

DIOPT Version :9

Sequence 1:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_495833.1	Gene:	sptf-2 / 188733	WormBaseID:	WBGene00011926	Length:	166	Species:	Caenorhabditis elegans

Alignment Length:	154	Identity:	71/154 - (46%)
Similarity:	93/154 - (60%)	Gaps:	11/154 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   676 STTTITTPSQSHLNMNISVASVG-----GAATGGGGGTATGEPKPRLKR---VACTCPNCTDGEK 732
            :.|....|.:||.:.:.|:.|:.     .:.:.....::.|..:...||   ..|||||| ...|
Worm     4 AATKFFRPWESHGSYHHSLPSISPPDSPASTSASSSSSSIGANELTTKRRKCERCTCPNC-KAIK 67

  Fly   733 HSDKKRQ--HICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRRTHT 795
            |.|:..|  |:|.:.||.|.|.||||||||||.|||:|||||.|..|||||.|||:|.||:||||
Worm    68 HGDRGSQHTHLCSVPGCGKTYKKTSHLRAHLRKHTGDRPFVCDWFDCGKRFDRSDQLIRHKRTHT 132

  Fly   796 GEKRFQCQECNKKFMRSDHLSKHI 819
            .|.||.|:.|.::|.|||||.:|:
Worm   133 KEYRFACKFCIRQFSRSDHLQQHL 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	59/97 (61%)
		C2H2 Zn finger	742..764	CDD:275368	15/21 (71%)
		zf-H2C2_2	756..783	CDD:290200	21/26 (81%)
		C2H2 Zn finger	772..794	CDD:275368	14/21 (67%)
		zf-H2C2_2	786..809	CDD:290200	12/22 (55%)
		zf-C2H2	800..822	CDD:278523	10/20 (50%)
		C2H2 Zn finger	802..822	CDD:275368	9/18 (50%)
sptf-2	NP_495833.1	COG5048	<75..156	CDD:227381	51/80 (64%)
		C2H2 Zn finger	82..101	CDD:275368	14/18 (78%)
		C2H2 Zn finger	109..131	CDD:275368	14/21 (67%)
		C2H2 Zn finger	139..156	CDD:275368	8/16 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454837at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14601
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6780
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050