DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spps and Klf9

DIOPT Version :9

Sequence 1:	NP_001262902.1	Gene:	Spps / 42882	FlyBaseID:	FBgn0039169	Length:	985	Species:	Drosophila melanogaster
Sequence 2:	NP_034768.2	Gene:	Klf9 / 16601	MGIID:	1333856	Length:	244	Species:	Mus musculus

Alignment Length:	192	Identity:	77/192 - (40%)
Similarity:	101/192 - (52%)	Gaps:	31/192 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   679 TITTPSQSHLNMN----ISVASV--------------GGAATGGGGGTATGEPKPRLKRVACTCP 725
            |:.|.::|.|::|    |...||              ....|...|.:.:..|:.|....:...|
Mouse    59 TLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGSAPSP 123

  Fly   726 ------NCTDGEKHSDKKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRS 784
                  ......||:.:|| |.|..:||.|||||:|||:||.|.|||||||.|:|..|.|:|:||
Mouse   124 LSLLHSGVASKGKHASEKR-HKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRS 187

  Fly   785 DELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETKGGNAP 846
            |||.||.|||||||:|:|..|.|:|||||||:||.:.|      .|.....||:..|...:|
Mouse   188 DELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRH------TEFHPSMIKRSKKALASP 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spps	NP_001262902.1	COG5048	<725..827	CDD:227381	60/107 (56%)
		C2H2 Zn finger	742..764	CDD:275368	14/21 (67%)
		zf-H2C2_2	756..783	CDD:290200	17/26 (65%)
		C2H2 Zn finger	772..794	CDD:275368	13/21 (62%)
		zf-H2C2_2	786..809	CDD:290200	15/22 (68%)
		zf-C2H2	800..822	CDD:278523	13/21 (62%)
		C2H2 Zn finger	802..822	CDD:275368	12/19 (63%)
Klf9	NP_034768.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..51
		COG5048	<78..234	CDD:227381	67/162 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..143		11/64 (17%)
		C2H2 Zn finger	145..167	CDD:275368	14/21 (67%)
		C2H2 Zn finger	175..197	CDD:275368	13/21 (62%)
		C2H2 Zn finger	205..225	CDD:275368	12/19 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910