Protein Alignment Spps and SP9

DIOPT Version :10

• Sequence 1: NP_001262902.1
• Gene: Spps / 42882
• FlyBaseID: FBgn0039169
• Length: 985
• Species: Drosophila melanogaster
• Sequence 2: NP_001138722.1
• Gene: SP9 / 100131390
• HGNCID: 30690
• Length: 484
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 126/331 - (38%)
• Similarity: 158/331 - (47%)
• Gaps: 67/331 - (20%)

  Fly   594 NSLSSLSIPASIQITALPQQATNTPNTPATTQPIPVSLPARSKVNAVT--TSSTQITIAPTGGQV 656
            :||.|.:..||:.    .|..|..|:..:.|.....|....|...|.:  .|::|..:|..|.:.
Human   202 SSLHSGAPQASLH----SQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKP 262

  Fly   657 VSVTTQARGATASIRSTNTSTTTITTPSQSHLNMNISVASVGGAATGGGGGTATGEPKPRLKRVA 721
            |            :.|.:.|:..:...:.|        |.:.|||....||::....:....|..
Human   263 V------------LPSYSDSSAAVAAAAAS--------AMISGAAAAAAGGSSARSARRYSGRAT 307

  Fly   722 CTCPNCTDGEKHSD------KKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKR 780
            |.||||.:.|:...      :|..|.|||.||.|||||||||:||||||||||||||:|.|||||
Human   308 CDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKR 372

  Fly   781 FTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETKGGNA 845
            ||||||||||.|||||||||.|..|||:||||||||||||||                 ..||..
Human   373 FTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTH-----------------NGGGGG 420

  Fly   846 PKSISTVNGIVTIEIP-----------GGGSAAAGSGASSVAATVAGSTVTPGGATIVQLPTVEA 899
            .|...:......:|.|           .|.|||..:.|::.||..|.:..:.||..       .|
Human   421 KKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAASAGGKE-------AA 478

  Fly   900 SGGGDS 905
            ||..||
Human   479 SGPNDS 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spps	NP_001262902.1	SP1-4_N	<281..>371	CDD:425404
		Atrophin-1	284..>630	CDD:460830	9/35 (26%)
		SP1-4_N	<713..741	CDD:425404	8/33 (24%)
		C2H2 Zn finger	742..764	CDD:275368	18/21 (86%)
		zf-H2C2_2	756..783	CDD:463886	23/26 (88%)
		C2H2 Zn finger	772..794	CDD:275368	18/21 (86%)
		zf-H2C2_2	786..809	CDD:463886	18/22 (82%)
		zf-C2H2	800..822	CDD:395048	17/21 (81%)
		C2H2 Zn finger	802..822	CDD:275368	16/19 (84%)
SP9	NP_001138722.1	SP9_N	19..333	CDD:411695	34/154 (22%)
		9aaTAD, inactive. /evidence=ECO:0000269|PubMed:31375868	178..186
		C2H2 Zn finger	337..356	CDD:275368	15/18 (83%)
		zf-H2C2_2	348..375	CDD:463886	23/26 (88%)
		C2H2 Zn finger	364..386	CDD:275368	18/21 (86%)
		zf-H2C2_2	378..401	CDD:463886	18/22 (82%)
		zf-C2H2	392..414	CDD:395048	17/21 (81%)
		C2H2 Zn finger	394..414	CDD:275368	16/19 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..446		11/53 (21%)