DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twin and AT3G18500

DIOPT Version :9

Sequence 1:	NP_732964.1	Gene:	twin / 42880	FlyBaseID:	FBgn0011725	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_001189925.1	Gene:	AT3G18500 / 821380	AraportID:	AT3G18500	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	482	Identity:	119/482 - (24%)
Similarity:	200/482 - (41%)	Gaps:	125/482 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 RVLPY--EIGKLFHLVILGLMGNPLQKEFMNIYNEPNGTQKLLTYMLDNLSFT---VNPPPQR-- 190
            |:||.  .:...||...|..:.  .:..|:...:..:|..........|.|::   .||.|:|
plant    19 RILPSGGHLSSGFHQCPLSSLS--FRSSFVCCSSSTSGPSDSNPESSSNRSYSRRWQNPLPRRQH 81

  Fly   191 ----PWLPLAK---PNKTRPAC----IFTVMCYNVLCDKYAT--RQMYGYCPSWALCWEYRKKSI 242
                |...:|:   .:.|.|..    .|||:.||:|.|..::  |::|.......|.|.|||:.|
plant    82 PDQIPSSQIARDWIDSDTTPVSQALERFTVVSYNILGDGNSSYHRELYSNVSVPYLKWGYRKRLI 146

  Fly   243 IDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERK---YVDGCAIF 304
            .:|:.....||||:||:               |.|..:||...:|......:|:   .|||||:|
plant   147 CEELIRLNPDIISMQEV---------------DKYFDLFSMMEKAGYAGSYKRRTGDNVDGCAMF 196

  Fly   305 FRASKFTLIKESLIEFNQLAMANAEGSDNMLNRVMPKDNIGLAALLKVKENAWEPMSEVTQISQP 369
            ::|.:|.:::...|||:|..|               :||:...|:|::::         :..|:.
plant   197 WKADRFGVLERENIEFSQFGM---------------RDNVAQLAVLELRK---------SNKSRK 237

  Fly   370 LLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEASHSFRPGHKNDSNAVQLLLCGDFNSLPDS 434
            :|:...|:.::|...||||.|...|.::...:      |.:.|.      :.::|||||||.|.|
plant   238 ILLGNIHVLYNPNQGDVKLGQVRSLCSKAHLL------SKKWGD------IPIVLCGDFNSTPKS 290

  Fly   435 GVVEFLGKGRVSMDHLDFKDM-GYKSCLQ----------------------------RLLSNDTN 470
            .:..||....:::...|.|:: |.|:|..                            |:.:...|
plant   291 PLYNFLASSELNVMEHDKKELSGQKNCRPTKVLETGSKSSNTITFRSFCSSWTKEEIRVATGQEN 355

  Fly   471 EF--THSFKLASAY-------------NEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVS 520
            .:  .|..||.|:|             .|.:.  |:|...|.|.:||::|: .|::|..:|..:.
plant   356 SYWAAHPLKLNSSYASVKGSANTRDSVGEPLA--TSYHSKFLGTVDYLWYS-DGLLPARVLDTLP 417

  Fly   521 NDWLRENKVVGCPHPHIPSDHFPLLVE 547
            .|.|.:.|  |.|...:.|||..|:.|
plant   418 IDVLCKTK--GLPCQELGSDHLALVSE 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twin	NP_732964.1	LRR_4	74..114	CDD:289563
		LRR_8	75..130	CDD:290566
		leucine-rich repeat	76..98	CDD:275378
		LRR_4	97..136	CDD:289563	1/2 (50%)
		leucine-rich repeat	99..121	CDD:275378
		leucine-rich repeat	122..144	CDD:275378	3/12 (25%)
		leucine-rich repeat	145..156	CDD:275378	1/10 (10%)
		Deadenylase_CCR4	209..550	CDD:197331	99/388 (26%)
AT3G18500	NP_001189925.1	EEP	111..445	CDD:294334	99/388 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810