| Sequence 1: | NP_732964.1 | Gene: | twin / 42880 | FlyBaseID: | FBgn0011725 | Length: | 567 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036250.2 | Gene: | NOCT / 25819 | HGNCID: | 14254 | Length: | 431 | Species: | Homo sapiens |
| Alignment Length: | 425 | Identity: | 96/425 - (22%) |
|---|---|---|---|
| Similarity: | 163/425 - (38%) | Gaps: | 119/425 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 168 GTQKLLTYMLDNLS---------FTVNPPPQRPWLPLAKPNK----------TRPA--------- 204
Fly 205 ---CIFT-----VMCYNVLCDKYAT-RQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIE 260
Fly 261 TEQFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAM 325
Fly 326 ANAEGSDNMLNRVMPKDNIGLAALLKVKENAWEPMSEVTQISQPLLVCTAHIHWD----PEFCDV 386
Fly 387 KLIQTMMLSNELKTIIDEASHSFRPGHKNDSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMDHLD 451
Fly 452 FKDMGYKSCLQRLLSNDTNEFTHSFKLASAYNEDIMPHTNYTFDFKG----IIDYIFYTKTGMVP 512
Fly 513 LGLLGPVSNDWLRENKVVGCPHPHIPSDHFPLLVE 547 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| twin | NP_732964.1 | LRR_4 | 74..114 | CDD:289563 | |
| LRR_8 | 75..130 | CDD:290566 | |||
| leucine-rich repeat | 76..98 | CDD:275378 | |||
| LRR_4 | 97..136 | CDD:289563 | |||
| leucine-rich repeat | 99..121 | CDD:275378 | |||
| leucine-rich repeat | 122..144 | CDD:275378 | |||
| leucine-rich repeat | 145..156 | CDD:275378 | |||
| Deadenylase_CCR4 | 209..550 | CDD:197331 | 82/348 (24%) | ||
| NOCT | NP_036250.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 20..41 | ||
| Deadenylase_nocturnin | 144..423 | CDD:197330 | 82/349 (23%) | ||
| Substrate binding. /evidence=ECO:0000269|PubMed:31147539 | 219..221 | 1/1 (100%) | |||
| Substrate binding. /evidence=ECO:0000269|PubMed:31147539 | 286..289 | 0/9 (0%) | |||
| Substrate binding. /evidence=ECO:0000269|PubMed:31147539 | 324..326 | 1/1 (100%) | |||
| Interaction with PPARG. /evidence=ECO:0000250|UniProtKB:O35710 | 343..353 | 2/34 (6%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5239 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||