| Sequence 1: | NP_732964.1 | Gene: | twin / 42880 | FlyBaseID: | FBgn0011725 | Length: | 567 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_849185.2 | Gene: | Cnot6l / 231464 | MGIID: | 2443154 | Length: | 555 | Species: | Mus musculus |
| Alignment Length: | 559 | Identity: | 321/559 - (57%) |
|---|---|---|---|
| Similarity: | 411/559 - (73%) | Gaps: | 29/559 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 27 KDKYDSAN-RRQQIFLSQEDIAAGKKTNWSGLEITGCVRNISPSLWEFEHLTALYLNDNQLLRLP 90
Fly 91 ADVGMLTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNNFLRVLPYEIGKLFHLVILGLMGNPL 155
Fly 156 QKEFMNIYNEPNGTQKLLTYMLDNLSFTVNPPPQRPWLPLAKPNKTRPACIFTVMCYNVLCDKYA 220
Fly 221 TRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETEQFYHFFLPELKNDGYEGIFSPKS 285
Fly 286 RAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMANAEGSDNMLNRVMPKDNIGLAALL 350
Fly 351 KVKENAW----EPMSEVTQISQPLLVCTAHIHWDPEFCDVKLIQTMMLSNELKTIIDEASHSFRP 411
Fly 412 GHKN-DSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMDHLDFKDMGYKSCLQRLLSNDTN----- 470
Fly 471 EFTHSFKLASAYNEDIMPHTNYTFDFKGIIDYIFYTKTGMVPLGLLGPVSNDWLRENKVVGCPHP 535
Fly 536 HIPSDHFPLLVELELMHTASQQAPP-----NG--LINRR 567 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| twin | NP_732964.1 | LRR_4 | 74..114 | CDD:289563 | 26/39 (67%) |
| LRR_8 | 75..130 | CDD:290566 | 38/54 (70%) | ||
| leucine-rich repeat | 76..98 | CDD:275378 | 13/21 (62%) | ||
| LRR_4 | 97..136 | CDD:289563 | 28/38 (74%) | ||
| leucine-rich repeat | 99..121 | CDD:275378 | 17/21 (81%) | ||
| leucine-rich repeat | 122..144 | CDD:275378 | 17/21 (81%) | ||
| leucine-rich repeat | 145..156 | CDD:275378 | 7/10 (70%) | ||
| Deadenylase_CCR4 | 209..550 | CDD:197331 | 209/350 (60%) | ||
| Cnot6l | NP_849185.2 | Required for interaction with CNOT1, CNOT3 and CNOT7. /evidence=ECO:0000250 | 1..152 | 84/143 (59%) | |
| leucine-rich repeat | 38..57 | CDD:275378 | 10/18 (56%) | ||
| LRR | <57..>183 | CDD:227223 | 75/125 (60%) | ||
| leucine-rich repeat | 58..80 | CDD:275378 | 13/21 (62%) | ||
| leucine-rich repeat | 81..103 | CDD:275378 | 17/21 (81%) | ||
| leucine-rich repeat | 104..126 | CDD:275378 | 17/21 (81%) | ||
| leucine-rich repeat | 127..138 | CDD:275378 | 7/10 (70%) | ||
| Nuclease domain. /evidence=ECO:0000250 | 158..555 | 231/407 (57%) | |||
| Deadenylase_CCR4b | 191..538 | CDD:197339 | 209/350 (60%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167833975 | |
| Domainoid | 1 | 1.000 | 416 | 1.000 | Domainoid score | I658 |
| eggNOG | 1 | 0.900 | - | - | E1_COG5239 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H100830 | |
| Inparanoid | 1 | 1.050 | 635 | 1.000 | Inparanoid score | I836 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S1162 |
| OMA | 1 | 1.010 | - | - | QHG57444 | |
| OrthoDB | 1 | 1.010 | - | - | D724242at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002437 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42848 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101771 | |
| Panther | 1 | 1.100 | - | - | O | PTHR12121 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3216 |
| SonicParanoid | 1 | 1.000 | - | - | X1441 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 17.750 | |||||