Protein Alignment CG6204 and Znfx1

DIOPT Version :10

• Sequence 1: NP_651229.2
• Gene: CG6204 / 42877
• FlyBaseID: FBgn0039165
• Length: 903
• Species: Drosophila melanogaster
• Sequence 2: NP_001028368.2
• Gene: Znfx1 / 98999
• MGIID: 2138982
• Length: 1909
• Species: Mus musculus
• Alignment Length: 1181
• Identity: 287/1181 - (24%)
• Similarity: 460/1181 - (38%)
• Gaps: 385/1181 - (32%)

  Fly    46 PPSEVGEYVMQHTRFSLTELTNALKMPAIDMFLYFLSDKRDLFENQVLATDNVKRVGLFVDVLWS 110
            ||.:.||...|..|.....|.:.|:....::.:             .|||.    :||
Mouse   123 PPQKPGEQPQQTKRLGYKFLESLLQKEPSEVAI-------------TLATS----LGL------- 163

  Fly   111 LCELELGGFDEVFLSAFSRQTALLDKIKNLLQAKAAVAKCDAESAL----ILSHSKWM--LLRAH 169
                      :..||..|.:.:.|..|..:|: ||..::.|.:|.|    ||::||::  .|.|:
Mouse   164 ----------KELLSHSSMKPSFLQLICQVLR-KACSSRIDRQSILHVLGILNNSKFLRVCLPAY 217

  Fly   170 KHGLLSHQGYELVELYKKLAPSFKSDMIDGLEAFTGNF---SHNVKGLIYPTLETLLGKDATKAP 231
            ..|:::....::...|    |...|::|..|:.....|   |.....::...|.|.|  :|.:|.
Mouse   218 VVGMITEPSPDIRNQY----PEHISNIISLLQDLVSVFPASSMQETSMLISLLPTSL--NALRAS 276

  Fly   232 N---EEEDEGLVS--DKVVKYVNALR--------------------------------------- 252
            .   |||.|..:.  ..::||:...|
Mouse   277 GVDIEEETEKNLEKVQAIIKYLQEKRRQGSLRVDTYTLVQAEAEGEVESYRAMPIYPTYNEVHLD 341

  Fly   253 -------------------------NLLREDFLAPLVEFVQQLRSGTDVDELKQQGLLWSDVHLT 292
                                     .||||||:.||.|.:.:|....:...|:::  .:.|:.:.
Mouse   342 EKPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILKLLQSFEDQCLRKR--KFDDIRIY 404

  Fly   293 LNPQFANAQ-RHSLVFLKVQF-TKESKNAYKTWLNS--IKSGTLLCLTTSLAFDDLILASVGYTE 353
            .:.:..... ..|.:..|||| ||..|  ...|.||  :..|:|:|::.. .|:..:.|:|...|
Mouse   405 FDARIITPMCSASGIVYKVQFDTKPLK--LVRWQNSKRLLYGSLVCMSKD-NFETFLFATVSNRE 466

  Fly   354 PEKLKEDCL-------SVQIVKQYNIGNAYNRPLIMFQAPVFFEPYLRVHNYLSTCSTEKFPMGR 411
            .|.|.:..:       |.|::......:::    :|.:...:||.|..|...|.....|..|..|
Mouse   467 HEDLCQGIVQLCFNEQSQQLLADVQPSDSF----LMVETTAYFEAYRHVLEGLQEVQEEDVPFQR 527

  Fly   412 YIVDGQMEIPPPAYMKPGVKLSF-----------------------NMKPFTLDKLP--EDLHLN 451
            .||.....:..|.|:..|.:..|                       .:..|...:.|  |.|.|:
Mouse   528 NIVQCDSYVRNPRYLLMGGRYDFTPLMENPSAMRKSLRGAEALRHPRINVFDFGQWPSKEALKLD 592

  Fly   452 ESQKTAFKEALCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKA----LGTGPIIVLTYTNNSLDK 512
            :||..|.:.||.:|.:|||||||||||::.:::|.:|:.|...    ..|.||:|:.|||::||:
Mouse   593 DSQMEALQFALTKELAIIQGPPGTGKTYVGLKIVQALLTNKSVWQINTQTFPILVVCYTNHALDQ 657

  Fly   513 FLVKI-SRYTQEILRFGNQSRDPQISKFNL-STTIKPEL---VPPRLKRIWWLVNCEYKEKFRNL 572
            ||..| ......|:|.|.:|....:.:|.| ....|.|.   :|..|:|.:..:..|.||..:.|
Mouse   658 FLEGIYGCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRTLPMHLRRAYMSIVTEMKESEQKL 722

  Fly   573 Q--------------------------------------------------------GL------ 575
            |                                                        ||
Mouse   723 QEGAQTLECTMHGVLREQHLEKYISAQHWESLMSGPVQDADWVCVQPSKHSMILEWLGLGVGSFT 787

  Fly   576 ----------YANFDGSEESYQD------------------------------------------ 588
                      .|..:|.||...:
Mouse   788 QSASPAGPENTAQAEGEEEEEGEEEGSLIEIAEEADLIQADRVIEEEEVVRPRRRKKEENGTDQE 852

  Fly   589 ----------------TLAAQE-------------------------KLNQV------------- 599
                            |.|..|                         |||.:
Mouse   853 LAKMLLAMRLDQEVPGTTAGPEQATEEWETQRGQKKKMKRRVKVELRKLNTMTKAEANGIQDVWQ 917

  Fly   600 -----------------------------------AERIETLRMVFQFFLAREKDLLAMTTTCAA 629
                                               |||:..||:.....:.::.:::.||||.||
Mouse   918 LDLSSRWQLYRLWLQMYQADTRRRILSYERQYRTWAERMAELRLQEDLHILKDAEVVGMTTTGAA 982

  Fly   630 RHNFLFRLLQSKCVLFEEAAEIQEAHIVACLTPHTEHVILVGDHKQLQPFSGSRKVP-----QIS 689
            ::..:.:.::.:.|:.|||||:.|||.:|.|:...:|:||:|||:||:|.:....:.     ::|
Mouse   983 KYRQILQQVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVS 1047

  Fly   690 LFERLIVAGLPFSRLNLQYRMRSCISELLVPSIYDELLCSESVKEYEDIRLMSKNLYFVQHNQPE 754
            |||||:...:||.|||.|:|||..|:.||.|.||.:|....||.:||.|:.:|.||:||:||.||
Mouse  1048 LFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPE 1112

  Fly   755 HCMSD-MSIGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQNYRSTVQVAS 818
            ..:.: .|..|.:||..:.:|.::|:.: :|..|.|.||:.|.||:.|::..:|....:.::|..
Mouse  1113 QEIQEGKSHQNQHEAHFVVELCQYLLCQ-EYLPSQITILTTYTGQLFCLRKLMPVKTFAGIKVHV 1176

  Fly   819 VDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVGNVTILKDTFPKIWNPI 883
            ||.:||.|.:|:||||||||..|::|||:..||:|||||||:..:|.:||:.:|...  .:|:.|
Mouse  1177 VDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQMLAKV--PLWSRI 1239

  Fly   884 VKRLKENNAIG 894
            :..|:|||.||
Mouse  1240 IHTLRENNQIG 1250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	EEXXEc_NFX1	449..708	CDD:350694	103/475 (22%)
		SF1_C_Upf1	710..888	CDD:350195	73/178 (41%)
Znfx1	NP_001028368.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		4/9 (44%)
		RecD	536..>629	CDD:440273	27/92 (29%)
		DEAD-like_helicase_N	591..>674	CDD:475120	35/82 (43%)
		DNA2	<652..1246	CDD:440729	152/596 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	787..813		4/25 (16%)
		EEXXEc_NFX1	<971..1066	CDD:350694	37/94 (39%)
		SF1_C_Upf1	1068..1244	CDD:350195	73/178 (41%)
		NF-X1-zinc-finger	1365..1410	CDD:100116
		NF-X1-zinc-finger	1453..1497	CDD:100116
		LELP1	1466..1559	CDD:464464
		PRK03918	<1597..>1808	CDD:235175
		DUF6539	1834..1878	CDD:466324