Protein Alignment CG6204 and HCS1

DIOPT Version :9

• Sequence 1: NP_651229.2
• Gene: CG6204 / 42877
• FlyBaseID: FBgn0039165
• Length: 903
• Species: Drosophila melanogaster
• Sequence 2: NP_012908.1
• Gene: HCS1 / 853852
• SGDID: S000001500
• Length: 683
• Species: Saccharomyces cerevisiae
• Alignment Length: 750
• Identity: 177/750 - (23%)
• Similarity: 318/750 - (42%)
• Gaps: 206/750 - (27%)

  Fly   246 KYVNALRNLLREDFLAPLVEFVQQLRSGTDVDELKQQGLLWSDVHL-------------TLNPQF 297
            |:::::::...:|     ::...:|.:...:.:|.|.||..:::||             .|.|..
Yeast     8 KFLSSIKHEREQD-----IQTTSRLLTTLSIQQLVQNGLAINNIHLENIRSGLIGKLYMELGPNL 67

  Fly   298 A---NAQRHSL----VFL--------------KVQFTKESKNAYKTWLNSI---KSGTLLCLTTS 338
            |   ..||..:    :.|              ||:...|..|..:...:.:   .|.|.  :|.:
Yeast    68 AVNDKIQRGDIKVGDIVLVRPAKTKVNTKTKPKVKKVSEDSNGEQAECSGVVYKMSDTQ--ITIA 130

  Fly   339 LAFDDLILASVGYTEPEKLKEDCLSVQIVKQYNIGNAYNRPLIMFQAPVFFEPYLRVHNYLSTCS 403
            |.....::|:..|:..:        :.|:|..|: ..|||          .|..:|..:.:|:..
Yeast   131 LEESQDVIATTFYSYSK--------LYILKTTNV-VTYNR----------MESTMRKLSEISSPI 176

  Fly   404 TEKFPMGRYIVDGQMEIPPPAYMKPGVKLSF-NMKPFTLDKLPEDLHLNESQKTAFKEALCREFS 467
            .:|  :.:|:|:.:..||...        || |:|.|.      :.:||:|||||...|:..:.:
Yeast   177 QDK--IIQYLVNERPFIPNTN--------SFQNIKSFL------NPNLNDSQKTAINFAINNDLT 225

  Fly   468 IIQGPPGTGKTHLSVQLVNS-LIQN--AKALGTGPIIVLTYTNNSLDKFLVKISRYTQE--ILRF 527
            ||.||||||||...::|:.. ||:|  .:.|..||      :|.|:|..|.:::.....  :||.
Yeast   226 IIHGPPGTGKTFTLIELIQQLLIKNPEERILICGP------SNISVDTILERLTPLVPNNLLLRI 284

  Fly   528 GNQSR--DPQ-------ISKFNLSTTIKPELVPPRLKRIWWLVNCEYKEKFRNLQGLYANFDGSE 583
            |:.:|  |..       :||.|  |.:|                                 |.|:
Yeast   285 GHPARLLDSNKRHSLDILSKKN--TIVK---------------------------------DISQ 314

  Fly   584 ESYQDTLAAQEKLNQVAERIET---LRMVFQFFLARE----KDL-----LAMTT--------TCA 628
            | ....:...:||....:|.|.   ::::.:....||    |||     :.:||        .|:
Yeast   315 E-IDKLIQENKKLKNYKQRKENWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCS 378

  Fly   629 A-RHNFLFRLLQSKCVLFEEAAEIQEAHIVACLTPHTEH------VILVGDHKQLQPFSGSRKVP 686
            . |.:..|:|..:  ::.:|.::..|..   |..|...|      ::|.||:|||.|...:....
Yeast   379 LYRDDPNFQLFDT--LIIDEVSQAMEPQ---CWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDK 438

  Fly   687 QI------SLFERLIVAGLPFSR------LNLQYRMRSCISELLVPSIYD-ELLCSESV------ 732
            .:      :||:|:|..   |.:      ||:||||...|.|....|:|: :||...:|
Yeast   439 NVIHNLETTLFDRIIKI---FPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLI 500

  Fly   733 ---------KEYEDIRLMSKNLYFVQHNQPEHCMSDMSI-GNLYEAGVLAKLTEFL--IQKAQYK 785
                     .|.:|...:....|..|.::.:....:.:| |:.|..|.:|.:.|.:  ::.....
Yeast   501 DLPTVDATPSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVP 565

  Fly   786 HSDIVILSPYNGQIECIKNALPQNYRST-VQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQA 849
            .:.|.::||||.|:..:|..:....:.| :::::||.|||.|.::::|||||||....:|||::.
Yeast   566 ENSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEVGFLKEE 630

  Fly   850 NRVCVALSRARWALYIVGNVTILK---DTFPKIWN 881
            .|:.||::|.|..|.:|||:.:|:   :.:.|.|:
Yeast   631 RRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWS 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	68/270 (25%)
		AAA_19	467..>513	CDD:289986	20/48 (42%)
		UvrD_C_2	688..869	CDD:304668	60/212 (28%)
HCS1	NP_012908.1	TIGR00376	15..679	CDD:273041	176/742 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810