Protein Alignment CG6204 and dna2

DIOPT Version :9

• Sequence 1: NP_651229.2
• Gene: CG6204 / 42877
• FlyBaseID: FBgn0039165
• Length: 903
• Species: Drosophila melanogaster
• Sequence 2: XP_021329958.1
• Gene: dna2 / 559535
• ZFINID: ZDB-GENE-090313-71
• Length: 1374
• Species: Danio rerio
• Alignment Length: 994
• Identity: 218/994 - (21%)
• Similarity: 376/994 - (37%)
• Gaps: 304/994 - (30%)

  Fly    23 SLKSLELQKNEEYIECPPSERKCPPSEVGEYVMQ--HTRFSLTELTNALKMPAIDMFLYFLSDKR 85
            |||..:....:|..|..||        :.|:..|  ||.....:....||:|: |..|    .|:
Zfish   516 SLKLTQADMRQEVEEYLPS--------ISEWAKQYLHTSPQAGQKQLTLKLPS-DGAL----SKQ 567

  Fly    86 DLFENQVLATDNVKRVGLFVDV---LWSLC-ELELGGFDEVF--LSAFSRQTALLDKI------- 137
            |. .:.|:.||       |||:   :|  | ...|.|..:|.  :....|....:::|
Zfish   568 DA-SSSVMVTD-------FVDIEENIW--CPRFGLKGKIDVTAGVKIHRRGRKPMERIVPLELKT 622

  Fly   138 ---KNLLQAKAAV---------AKCDAESALILSHSKWMLLRAHKHGLLSH--QGYELVELYKKL 188
               .|.::.::.|         .:||.|:..::     .|.....|.::.:  ...||:::...|
Zfish   623 GKESNSIEHRSQVILYTLMSSARRCDPEAGFLV-----YLKTGSLHPVVGNHMDRRELIKIRNSL 682

  Fly   189 APSFKSDMIDGLEAFTGNFSHNVKGLIYPTLETLLGKDATKAPNEEED---EGLVSD-KVVKYVN 249
            |                   |::            |.:..|...:.:.   ..:||| :..||..
Zfish   683 A-------------------HHI------------GNNLIKVDGKSQMAQLPAIVSDQQTCKYCP 716

  Fly   250 ALRN------LLREDFLAPLVE----FVQQLRSGTDVDELKQQGLLWSDVHLTLNPQFANAQRHS 304
            ..||      .:..|.:....|    |||     ::.:.|.|       |||    |:.:   |.
Zfish   717 QKRNCAIYNRAVERDPVEKCSENPQAFVQ-----SESEHLSQ-------VHL----QYFS---HW 762

  Fly   305 LVFLKVQ-FTKESKNAYKT-WLNSIK--------------SGTLLCLT----------------- 336
            |:...:: .|.|:|...:. ||.:.:              :|.:..|:
Zfish   763 LLLCSLEALTMENKGGRRNIWLQTAQQREKIGGCAGNMRLAGGVSILSDGVYKHSFERKEGEQTL 827

  Fly   337 TSLAFDDLILASVGYTEPEKLKEDCLSVQIVKQYNIGNAYNR-------PLIMFQAPVFF----- 389
            |.|...|.|:.|         .:|.:.:.:...|....|.||       .|..:.:...|
Zfish   828 TGLIVGDRIVVS---------DQDSVLIGLSTGYVTEIAVNRVTCSLDKNLSKYSSNTVFRLDQD 883

  Fly   390 EPYLRVHNYLSTCS--TEKFPMGRYIVDGQMEIPPPAYMKPGVKLSFNMKPFTLDKLPEDLH--- 449
            |....:..:|...|  .|..|....:.:..:|..||.::.   .||        ..||.|..
Zfish   884 EGAGGLSTHLGNLSMLMENTPTSERLRELIVEFRPPQFID---SLS--------SVLPRDAKDIV 937

  Fly   450 ------LNESQKTAFKEA-LCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTGPIIVLTYTN 507
                  ||:.||.|.|:. |.:::::|.|.||||||    ..:.:|::...|.|.. :::.:||:
Zfish   938 SNILKGLNKPQKQAMKKVLLSKDYTLIVGMPGTGKT----TTICTLVRILHACGFS-VLLTSYTH 997

  Fly   508 NSLDKFLVKISRYTQEILRFGNQSRDPQISKFNLSTTIKPELVPPRLKRIWWLVNCEYKEKFRNL 572
            :::|..|:|:.|:....||.|.    ||        .:..|::|
Zfish   998 SAVDNILLKLKRFKIGFLRLGR----PQ--------KVHHEILP--------------------- 1029

  Fly   573 QGLYANFDGSEESYQDTLAAQEKLNQVAERIETLRMVFQFFLAREKDLLAMTTTCAARHNFLFRL 637
                    .:||:.:            |:.|:||..:.|.:   .::|:..||....:|....|.
Zfish  1030 --------FTEEACR------------AKGIQTLEELEQLY---SRELIVATTCMGVKHPIFSRR 1071

  Fly   638 LQSKCVLFEEAAEIQEAHIVACLTP--HTEHVILVGDHKQLQPFSGSRKVPQI----SLFERLIV 696
            ....|:: :||::|.:.   .|:.|  :.:..:|||||:||.|...:.:...:    |||:||..
Zfish  1072 RFDFCIV-DEASQISQP---VCIGPLFYAQRFVLVGDHQQLPPIVQNAEARSLGMDESLFKRLEH 1132

  Fly   697 AGLPFSRLNLQYRMRSCISELLVPSIYD-ELLCSESVKEYEDIRLMSK-------NLYFVQ---- 749
            ......:||:||||.|.|..|....:|: .|.|.........::|.|:       .||..|
Zfish  1133 HRDAVVQLNVQYRMNSAIMSLSNALMYEGRLECGSEKTANAVLQLPSRAQAEEELELYVCQPQYS 1197

  Fly   750 --------HNQPEHCMSDMS------------IGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSP 794
                    .|.|. |..|.|            |.|..||.::..|...|: ||..:..||.:::|
Zfish  1198 AWVQAALEPNSPV-CFLDTSEVPAPETVEKSGISNHTEAVLVQGLVTLLL-KAGCRACDIGVIAP 1260

  Fly   795 YNGQIECIKNALPQNYRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIG-FLRQANRVCVALSR 858
            |..|::.|.:.|..:....::|.:||.:||.:.:::::|.||||..|.:| .|:...|:.||::|
Zfish  1261 YRQQLKVISSLLQGDAFKALEVNTVDKYQGRDKSVIIVSFVRSNAEGNLGELLQDWRRLNVAITR 1325

  Fly   859 ARWALYIVGNVTILKDTFP 877
            |:..|.::|:...|:...|
Zfish  1326 AKHKLLMLGSAPTLRRYAP 1344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	56/241 (23%)
		AAA_19	467..>513	CDD:289986	14/45 (31%)
		UvrD_C_2	688..869	CDD:304668	62/217 (29%)
dna2	XP_021329958.1	Dna2	391..602	CDD:312281	29/108 (27%)
		Cas4_I-A_I-B_I-C_I-D_II-B	<579..721	CDD:321087	29/179 (16%)
		AAA_11	788..1354	CDD:331082	148/644 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910